Full-Time

Manufacturing Equipment Engineer 1

Updated on 9/16/2026

Illumina

Illumina

5,001-10,000 employees

Develops sequencing platforms and consumables

Compensation Overview

$68.4k - $102.6k/yr

+ Bonus or commission + Equity

No H1B Sponsorship

San Diego, CA, USA

In Person

Travel up to 10% is required.

Category
Mechanical Engineering (1)
Required Skills
Microsoft Office

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Requirements
  • Typically requires 0 to 2 years of previous professional experience.
  • Proficiency in computer and Microsoft Office applications.
  • Skill in data collection techniques with strong hands-on capabilities.
  • Experience working within high-volume manufacturing environments and with spare parts used in manufacturing equipment.
  • Familiarity with optical, mechanical, electrical, and/or fluidic systems.
  • Proficiency in interpreting electrical and mechanical schematics.
  • Experience using engineering troubleshooting tools and structured problem-solving methods.
  • Foundational knowledge of equipment reliability, preventive maintenance, calibration, repair, and spares-management practices.
  • Familiarity with internal instrument communication and control interfaces, such as programmable logic controller/input-output, RS232, sensors, and related control systems, where applicable.
  • Good mathematical and analytical skills.
  • Good verbal and written communication skills in English.
  • Mechanical aptitude.
  • Knowledge of Good Manufacturing Practice and Good Documentation Practice.
  • Ability to work a flexible schedule or rotational shifts, including weekends.
  • Willingness to travel up to 10%.
Responsibilities
  • Complete tasks independently with minimal supervision and report and track progress through a digital ticketing system.
  • Escalate issues appropriately to engineers or supervisors and engage in troubleshooting under guidance.
  • Plan, coordinate, and execute concurrent calibrations, preventive maintenance, repairs, supplier support, and project activities according to established instructions.
  • Support the development, execution, and continuous improvement of preventive maintenance procedures to improve manufacturing equipment availability and reliability.
  • Assist engineers in troubleshooting and reducing recurring or systematic equipment failures using structured problem-solving methods, equipment data, maintenance history, and ticketing-system trends.
  • Support installation, qualification, startup, and modification activities for manufacturing equipment and instrumentation under engineering guidance.
  • Partner with vendors, engineers, operations, and cross-functional teams to resolve equipment issues, improve supportability, and sustain production readiness.
  • Monitor the technical performance of equipment and manage spares inventory within assigned areas of responsibility.
  • Provide support for computer hardware and software procedures and troubleshooting efforts.
  • Collaborate within a team environment to improve equipment reliability, safety, compliance, and continuous improvement.
  • Perform required physical activities including standing, sitting, walking, climbing stairs or ladders, kneeling, crouching, wearing safety gear, and lifting or moving equipment up to 50 pounds.
Desired Qualifications
  • Previous experience in the life sciences, pharmaceutical, or medical device industries.

Illumina provides integrated sequencing platforms and related consumables for analyzing genetic variation and biological function. Its instruments range from high-throughput NovaSeq systems to benchtop MiSeq/iSeq units, all built on sequencing-by-synthesis technology acquired from Solexa. Revenue comes from instrument sales plus a recurring stream of consumables, reagents, library preparation kits, and services. The company differentiates itself with a broad end-to-end ecosystem and strategic acquisitions (Solexa, GRAIL, SomaLogic) that expand capabilities into multiomics and clinical diagnostics.

Company Size

5,001-10,000

Company Stage

IPO

Headquarters

San Diego, California

Founded

1998

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Simplify Jobs

Simplify's Take

What believers are saying

  • Illumina raised 2026 revenue guidance to $4.60 billion-$4.64 billion after Q2 strength.
  • S&P 500 inclusion on September 21, 2026 should drive passive-fund buying.
  • Clinical volume reached 78% NovaSeq X conversion, supporting recurring consumables growth.

What critics are saying

  • FTC and Fifth Circuit GRAIL litigation still threatens forced divestiture and management distraction.
  • Research consumables declined in 2026 while clinical demand carried growth, exposing narrow dependence.
  • BGI and Thermo Fisher keep pressuring sequencing pricing, risking margin compression by 2027.

What makes Illumina unique

  • NovaSeq X drives clinical sequencing workflows, with 95 placements in Q2 2026.
  • Illumina pairs sequencing, DRAGEN software, and multiomics tools into one platform.
  • The new WGS MRD research solution broadens Illumina beyond core sequencing instruments.

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Benefits

Professional Development Budget

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

0%

2 year growth

-2%
Yahoo Finance
Sep 9th, 2026
Illumina joins S&P 500 on 21 September following 112% stock surge

Illumina will join the S&P 500 index on 21 September, alongside Bloom Energy and Everpure, replacing Molson Coors Beverage, The Trade Desk, and Builders FirstSource. S&P Dow Jones Indices announced the rebalancing on Friday. The San Diego-based genetic sequencing company, valued at $33 billion, has returned 112% over the past 12 months. The inclusion will trigger buying from passive funds tracking the index. Illumina is moving from the S&P MidCap 400, signalling its growth into large-cap status. In the second quarter, the company reported revenue of $1.16 billion, up 9.5% year-over-year, with earnings per share rising approximately 10% to $1.31.

Yahoo Finance
Aug 26th, 2026
Illumina beats Q2 expectations with $1.16B revenue, raises full-year guidance

Illumina reported second-quarter revenues of $1.16 billion, marking a 9.4% year-on-year increase that exceeded analyst expectations by 2.5%. The DNA sequencing and microarray technology company delivered strong organic revenue performance and raised its full-year earnings guidance. Chief executive Jacob Thaysen attributed the results to growing momentum in sequencing-intensive applications among clinical customers. The company increased its revenue and earnings guidance for the year based on this performance. Illumina's shares rose 10% following the earnings announcement and currently trade at $225.55. The results came as part of a strong second quarter for the life sciences tools and services sector overall, with the 20 tracked stocks in the group beating revenue estimates by 2.6% on average.

GenomeWeb
Aug 14th, 2026
Illumina secures $1B credit facility with Bank of America, launches note offering

Illumina has entered into a $1 billion credit facility with Bank of America serving as administrative agent. The genomics company announced the agreement after market close on Thursday. The credit facility also includes an underwriting agreement for a note offering, though specific terms were not disclosed in the announcement.

AktienSensor
Aug 12th, 2026
Illumina raises $750M with 2029 senior notes to refinance debt and lower cost of capital

Illumina has filed to issue senior notes maturing in 2029, expecting to raise approximately $750 million. The unsecured notes will rank equally with the company's other unsecured debt and feature a yield near the current US Treasury benchmark. Proceeds will primarily repay an earlier 4.65% note due in September 2026. By extinguishing higher-cost debt, Illumina aims to reduce its interest burden and improve its debt-to-equity ratio. The company expects its weighted average cost of capital to decrease from 5.8% to an estimated 4.9%. The notes include a make-whole redemption clause and a change-of-control provision requiring Illumina to purchase notes at 101% of principal plus interest. Illumina holds Moody's A-3 and S&P A- credit ratings. The refinancing supports ongoing investment in next-generation sequencing platforms, data analytics, and cloud-based services whilst enhancing financial flexibility for strategic acquisitions and R&D funding.

PR Newswire
Jul 30th, 2026
Illumina raises 2026 guidance on strong Q2 results: $1.16B revenue, up 9.5%

Illumina reported second quarter 2026 revenue of $1.16 billion, up 9.5% from the prior year period. The San Diego-based genomics company posted GAAP diluted earnings per share of $1.35 and non-GAAP diluted earnings per share of $1.31. Chief executive Jacob Thaysen said momentum built through the first half of 2026 as the company's technology enabled clinical customers to expand sequencing-intensive applications. He noted that demand for NovaSeq X remains high. Based on this performance, Illumina raised its full-year 2026 revenue guidance to $4.60-$4.64 billion, up from prior guidance of $4.52-$4.62 billion. The company increased its non-GAAP diluted earnings per share guidance to $5.30-$5.40, versus prior guidance of $5.15-$5.30.