SRA/Associate Scientist I
Cell Biology, In Vivo Target Discovery
What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.
Editas Medicine is seeking a highly motivated scientist at the level of Associate Scientist I to join our Gene Editing Target Discovery group. In this role, you will support on-going efforts to develop gene editing therapies for ocular indications and for exploratory new targets in non-ocular tissues/organs. You will contribute to the development of cell-based assays and ex vivo methods to evaluate the extent and effects of gene editing. An ideal candidate should have a background in gene editing, as well as a track record of creative thinking and collaboration. The successful candidate will be part of a dynamic, multidisciplinary discovery team dedicated to the development of gene editing-based therapies for major disease indications.
- Work collaboratively across the organization to support multiple programs and execute on goals
- Develop and optimize cell-based assays (primary and immortalized cells) to evaluate editing
- Plan, perform, and analyze DNA/RNA extraction, qPCR, and ddPCR
- Develop and optimize protein quantification assays such as Jess automated western blot and ELISA
- Aid in the formulation and characterization of lipid nanoparticles
- Establish relevant ex vivo models to determine transfection or transduction and editing
- Compile and present data, and assist in authoring protocols and technical reports
- Share responsibility in maintaining lab equipment and reagent inventory
- Cross-train personnel on technical methods and provide guidance to junior research associates
- Document all experimental work, supporting information, and data in an electronic lab notebook in a timely manner
- BS degree with 5+ years of experience or MS degree with 3+ years of experience in cell biology or related field
- Experience running immunoassays (immunofluorescence, Jess automated western blot and ELISA)
- Experience with mammalian cell culture
- Proficient in molecular biology analyses such as qPCR and ddPCR
- Results-driven with excellent attention to details and ability to independently execute protocols
- Excellent written and oral communication skills
- Ability to work in a team-oriented, multidisciplinary environment
- Experience with formulating and working with lipid nanoparticles
Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.