Position Overview:

Beam is searching for a Sr Dir/Vice President - Program Leader (PL) to provide overarching strategic and operational leadership for our lead assets in the In Vivo editing portfolio.  The focus will be on developing novel treatments for serious liver diseases with base editing, a next-generation form of CRISPR capable of making single-base changes in DNA.

Reporting to Chief Executive Officer (CEO), the PL will work closely with the cross-functional Program Team and other key stakeholders across Beam to direct overall planning and execution of program activities.  The PL will cultivate a deep understanding of the science, patient needs, competitive landscape, and technology and market trends relating to the program, and will create short and long-term objectives for science, strategy, and execution that lead to regulatory approvals and successful commercialization of a transformative base editing medicine for patients.

Responsibilities:

• Provide product development leadership, from development through commercialization and life cycle management.
• Accountable for program strategic planning, commercial, development and research decisions, risk identification and management, program resourcing/budgeting, cross-functional problem-solving, market assessment, indication prioritization and overall product development/lifecycle considerations.
• Lead strategic direction and planning in alignment with broader portfolio and corporate strategy.
• Responsible for leading the cross-functional Program Team in the development of strategies and operational plans that support the program’s short and long term development.
• Accountable for making (or delegating) day-to-day program decisions at the team/functional level, including scientific decisions, and recommending/coordinating corporate decisions on program strategy/investments.
• Collaborate effectively with internal and external partners ensuring alignment of program goals.
• Provide executive leadership with insights into program level strategic objectives, decisions, and execution.
• Ensure thorough and comprehensive organizational communication and understanding of program goals, objectives, and timelines.
• Contribute at the portfolio level to improve Beam’s overall approach to drug development, including identifying and resolving bottlenecks, sharing lessons learned, and supporting the advancement of other programs across Beam.

Qualifications:

• BS/BA in a relevant academic field; MBA, MD, PhD, or other graduate degree strongly preferred.  Overall preference for candidates with scientific training.
• Extensive experience and track record with development of innovative, first-in-class medical products required.
•  Genetic disease, gene therapy, and/or cell therapy experience strongly desired, including with the clinical, regulatory, and CMC issues involved with complex genetic medicine and biologic drug products.
• 12+ years’ experience within the pharma/biotech/biopharma space in roles of progressively increasing responsibility.
• Proven track record in a program leadership role or other cross-disciplinary background with successful team leadership experience required.
• Demonstrated ability to lead teams without direct reporting responsibility; exceptional interpersonal skills and collaborative nature with strong ability to influence, motivate, inspire, encourage and develop others.
• Drug development experience required with the ability to understand and critically assess clinical development plans, regulatory strategy, commercial strategy and seamlessly connect to execution including determining resource needs, budgets, and timelines
• Driven by patient needs and comfortable operating in a highly scientific and technical environment while dealing with ambiguity
• Strong collaboration, decision-making and conflict management skills with demonstrated proficiency.
• Excellent verbal and written communication skills including strong formal presentation skills and the ability to communicate complex scientific information in an understandable manner.
• Sophisticated understanding of the evolving scientific, clinical, regulatory, competitive, and economic trends impacting the industry, and able to adapt operational strategies accordingly.
• Experience in both large and small company environments a plus.

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