Senior Research Scientist
Blood Cell Biology
Confirmed live in the last 24 hours

501-1,000 employees

Blood test cancer detection biotech company
Company Overview
Freenome's mission is to empower everyone to prevent, detect, and treat disease by developing high-quality diagnostic tests. The developing next-generation blood tests powered by their multiomics platform to discover the body’s earliest warning signs of cancer, and develop accessible tests to detect cancer in its earliest, most treatable stages.
AI & Machine Learning
Data & Analytics

Company Stage

Series D

Total Funding





South San Francisco, California

Growth & Insights

6 month growth


1 year growth


2 year growth

San Bruno, CA, USA
Experience Level
Desired Skills
Lab & Research
Biology & Biotech
  • Ph.D., M.D., or equivalent industry experience in blood physiology, hematology, blood biochemistry, immunology, cell biology, or a related field
  • In-depth knowledge of the proteome and/or transcriptome of any of the following blood fractions: platelet, RBC or neutrophils
  • Demonstrated expertise on functional characterization of platelets, neutrophils or RBCs
  • Practical experience with genomics and/or proteomic profiling methods on blood cells
  • Extensive hands-on experience using differential centrifugation, density gradient centrifugation, MACS or FACS workflows for the depletion, enrichment or isolation of blood cells, e.g., platelets, RBCs and neutrophils
  • Deep understanding of analytical techniques for blood cell characterization at molecular and cellular levels, e.g., flow cytometry, microscopy, qPCR
  • Excellent creative thinking, scientific problem-solving, and communication skills and demonstrated ability to collaborate with others in the same and adjacent disciplines
  • List the job responsibilities that are important and impactful for this role
  • Apply fundamental understanding of platelet, RBC and neutrophil biology to develop assays for characterizing cellular content in blood and plasma samples
  • Design and prototype blood cell-based sample QC assays for cell-free biomarker discovery studies
  • Collaborate with Computational Research teams to integrate blood cell-based QC assay readout into cell-free DNA or protein assay models to improve test performance
  • Design and execute studies to evaluate the impact of preanalytical variables (including sample collection, shipping, and storage conditions) on blood cell stability in a variety of sample collection devices
  • Identify, evaluate and/or prototype new technologies for blood cell stabilization
  • Establish scalable method for blood cell depletion, enrichment or fractionation
  • Collaborate with Genomics and Proteomics teams to rapidly iterate on functional testing and improve on blood cell stabilization and isolation workflows
  • Identify, evaluate or develop novel blood cell-based biomarker research technologies and incorporate them into Freenome's discovery platform
Desired Qualifications
  • Baseline knowledge of blood cell-free fractions and analytes (e.g., plasma, cfDNA, cfRNA, EVs, lipoproteins)
  • Familiarity with the stability profile of a diverse set of blood analytes, including cells, DNA, RNA, proteins
  • Broad knowledge of common cell preservatives and fixatives and familiarity with their mechanisms of action
  • Broad knowledge of immunoassays, including western blotting, ELISA,, MSD, or Luminex
  • Practical experience with primary blood cell culture and aseptic technique
  • Experience mentoring and training research associates and junior scientists
  • Prior experience with blood-based biomarker research