Senior Bioinformatics Analyst

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The University of Miami/UHealth Department of SCCC has an exciting opportunity for a full time Sr. Bioinformatics Analyst to work in the UHealth Medical campus in Miami, FL.

JOB SUMMARY

As a Sr. Bioinformatics Analyst, you will be responsible for the bioinformatics and data analytics needs of the Cancer Proteomics Shared Resource. You will be actively involved in mass-spectrometry based proteomics data generation, processing, quality assurance analytics and visualization. 

CORE JOB FUNCTIONS

• Perform searches to interpret m/z and intensity data into the amino acid sequence information, post translational modifications, and assemble that data into protein-based quantitative results.

• Perform statistical analysis on label free quantitation, SILAC, and mass barcode (TMT) results to generate volcano plots and results in other visualization space(s).

• Organize, maintain, and version control FASTA formatted databases for protein and peptide ID searches. • Manipulate RNA-seq data for searching against mass spectrometry-based protein and peptide mass and intensity data.

• Develops and maintains next generation data analysis pipelines.

• Assists in analysis pipeline and algorithms development and validation.

• Extracts feature of interest from data relating to specific biological questions.

• Contributes to the development and maintenance of genomic and clinical databases.

• Performs statistical and integrative data analysis on genomics and clinical data.

• Supervises team members and other data analysts.

• Establishes standard operating procedures, documentation, and scripts to generate custom reports.

• Progresses material for bioinformatics tutorials and training courses.

• Tests the characterization and integration of diverse third-party bioinformatics algorithms.

• Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

CORE QUALIFICATIONS
Education: Bachelor’s Degree in relevant field. Master’s or PhD preferred in bioinformatics, applied mathematics, or large data analysis.

Experience: Minimum 3 years of relevant experience

Knowledge, Skills and Attitudes:

• Skill in collecting, organizing, and analyzing data.

• Ability to recognize, analyze, and solve a variety of problems.

• Ability to exercise sound judgment in making critical decisions.

• R-scripting and/or pearl scripting skills required. 

• Exceptional computer skills. 

• Excellent written and verbal communication skills. 

• Proficiency in MaxQuant, Sequest, Mascot, and Proteome Discoverer software tools. 

• Self-starter, diligent individual contributor, as well as delightful to work in a team environment. 

• Desire to apply proteomics towards improving quality of life and improving cancer diagnosis and care.

• A strong publication record is desired but not required.

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The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.

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