Senior Principal Computational Biologist

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What this position is all about:

Are you a highly motivated and detail-oriented computational biologist passionate about understanding complex biological systems and disease through single-cell omics and large-scale patient datasets? This role offers a unique opportunity to contribute to the development and application of Cellarity’s platform. Specifically, you will identify disease-associated states from cell atlases and use our single-cell AI models to predict chemical entities that revert these states to healthy.

You will be part of a dynamic and innovative computational team focused on generating high-impact insights. Collaborating closely with world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians, and technologists, you’ll help co-develop hypotheses, build proprietary data assets, and advance exploratory drug programs.

If you’re excited about applying your skills to real-world therapeutic challenges, working with proprietary, high-quality datasets, and learning from leading experts across disciplines, we want to hear from you.

What you would be responsible for:

• Apply computational biology and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets, with a focus on large-scale scRNA-seq & snRNA-seq disease atlases. 
• Develop & lead data analysis strategies and ideation across diverse biological and clinically relevant projects with internal and external stakeholders.
• Act as the computational biology co-lead on drug programs, working with experimental scientists to ensure that study designs & data are properly interrogated to deliver high value readouts.
• Present your results in an interdisciplinary team of biologists, chemists, clinicians, technologists, and other machine learning colleagues in meetings covering cross-functional project teams, functional teams, to whole company and management meetings. 

What experiences will you need:

• Ph.D. or equivalent in biology, computational biology, or related scientific field. 
• 4+ years of relevant industry experience.
• Extensive experience in analyzing and deriving hypothesis from single-cell transcriptomic data, preferably also with large-scale single-cell atlases. 
• Demonstrated scientific understanding of molecular and systems biology, diverse molecular data types, and analysis tools. 
• Practical programming and scripting skills, preferably in Python. 
• Fast learner, analytical thinker, creative, "hands-on", strong communication skills.
• Able to work both independently and as part of a team. 

What sets you apart:

• Background in metabolic or liver diseases, autoimmune disease, or hematology.
• Experience with generating, analyzing, and deriving hypotheses from other single-cell omics data types or large-scale clinical datasets.
• Experience driving an impactful and relevant project within industry.
• Background in statistics or machine learning.
• Experience with clinical or biological data.
• Interested in learning any of the above. 

What it’s like to work at Cellarity

At Cellarity, we

• Push Boundaries: We create a legacy with breakthrough science in service of patients.
• Inject Energy: We build strengths from different perspectives and tell it like it is
• Own it: We transcend our job descriptions and relentlessly follow through on our commitments.
• Go all out: We work quickly and with conviction.

Company Summary: Cellarity’s mission is to fundamentally redesign the way drugs are created for the sake of bringing new hope to patients.  By shifting the focus from a single target to the underlying cellular dysfunction, we unravel the complexity of disease biology and create medicines that were never before possible. The company has developed unique capabilities that link biology and chemistry with high dimensional -omic data from which we design medicines against the cellular signature of disease. The Cellarity platform allows us to uncover new biology in diseases even in the absence of known causal targets. The company has drug discovery programs underway in several disease areas, including metabolic disease, hematology, and immunology. Cellarity’s goal is to grow into a fully integrated next generation Biotech company driving a new age in drug creation.

Cellarity is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Cellarity does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Cellarity or its employees is strictly prohibited unless contacted directly by Cellarity’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Cellarity, and Cellarity will not owe any referral or other fees with respect thereto.

The salary range for this role is $140,000 - $206,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Cellarity currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Cellarity’s good faith estimate as of the date of publication and may be modified in the future.