About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who want to challenge status quo, and who lead with the desire to work on novel ideas. As a Research Associate, Molecular Biology, you will report to the Principal Scientist - Cell Characterization to perform the collection and quality control analysis of cell samples for genomic and epigenomic assays, as part of Sana’s Cambridge Stem Cell Sciences group. You will work closely with stem cell scientists to coordinate experiments and sample analysis, using assays such as flow cytometry and cell sorting, single cell RNA-sequencing including captures and library generation, and downstream validation studies including qPCR and ddPCR. Your role will include diverse bench work spanning the functions of the Stem Cell Sciences program.

What you’ll do

• Perform DNA and RNA-based genomic assays, including both bulk and single cell genomic and epigenomic approaches
• Capture and analyze cell samples – both from culture and dissected tissues - using flow cytometry, fluorescence activated cell sorting, and histological approaches
• Establish and process sequencing libraries for transcriptomic and epigenetic analysis
• Assure the quality, integrity, and documentation of all data collection including compliance with all relevant lab safety and biosafety regulations.

What we’re looking for

The successful candidate should have significant experience in bench cellular and molecular biology techniques, including the proper handling of DNA and RNA species required for genomics-based assays. A highly qualified candidate will also have significant experience with flow cytometry including cell sorting. The candidate is expected to have the capacity to present scientific data and assure the quality of data collection. Specific requirements are as follows:

• BA/MA in cell biology or molecular biology, with an emphasis in stem cell biology or neuroscience, and at least 2 years of practical laboratory experience, whether full-time or while in training
• Experience in flow cytometry, including sorting of cells based on fluorescent labels
• Experience with single cell genomic assays such as 10x Genomics platforms is required
• Excellent interpersonal, communicative, and problem-solving skills
• Proficiency with MS Office, and with standard programs for statistical analysis (e.g., GraphPad Prism) and flow cytometry analysis and quantification (e.g., FlowJo)
• Demonstrate the ability to act independently and with initiative, while integrating effectively into a larger team to advance shared goals.

What will separate you from the crowd

• Background in cell biology, neurobiology, or stem cell biology
• Experience in cell dissociation and sorting from rodent tissue
• Experience with library construction for Illumina sequencing platforms

What you should know

• The full-time position will be in Cambridge, MA, with full-time on-site work required
• The base pay range for this position at commencement of employment is expected to be between $75,000 – $88,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience