Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

We are looking for an (Associate) Director of R&D to support the development of new assays and processes for deployment in our clinical lab related to Tempus’s liquid biopsy portfolio in oncology. This role involves leading a team towards the execution of advanced molecular techniques toward the development of the most advanced sequencing platform in cancer care.

What You’ll Do:

• Lead a development and validation team from project inception through launch including sample selection, hands-on laboratory validation, establishing workflow and SOPs, and authoring validation plans and summaries
• Ensure activities are consistent with project critical path and respond appropriately to changing priorities
• Facilitate smooth transfers of developed workflows into clinical lab environments
• Evaluate emerging molecular and sequencing technologies and align these to business initiatives and product portfolio needs
• Mentor scientific staff on experimental design, continuous learning, and time management
• Conduct troubleshooting and quality control initiatives
• Assist with the development of automated processes
• Provide flexible support for other activities in the clinical Next Generation
• Sequencing lab, including emerging technology assessment, LIMS consulting, instrument troubleshooting, etc.

Qualifications:

• Master’s degree with 10+ years experience or Ph.D. with 5+ years experience in molecular techniques
• Strong analytical and conceptual capabilities, interpersonal skills, and ability to communicate with clarity
• Highly organized and systematic, superb attention to detail, and ability to complete tasks with a high degree of accuracy
• Track record of assay and/or product development
• Hands-on experience with any of the following molecular methods is highly desired:
  • NGS library preparation methods
  • Knowledge of liquid biopsy in oncology space
  • PCR methods such as: PCR, qPCR, RT-PCR, ddPCR
  • Nucleic acid ligations
  • Nucleic acid analysis such as: quantitation by absorbance/fluorescence, gel & capillary electrophoresis
  • Magnetic bead-based DNA/RNA purification and size selection
  • MLPA
  • Sanger Sequencing
  • DNA hybridization arrays

Highly Desirable:

• Thrives in a fast-paced environment
• Experience with robotics and automated liquid handling systems
• Experience in validation of clinical assay validation
• Knowledge of LIMS platforms and various computer systems
• Experience developing and validating assays according to various US and international regulatory body requirements

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