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Sr. Scientist, Protein Sciences Research
Posted on 2/2/2022
San Bruno, CA, USA
Experience Level
Desired Skills
Data Analysis
  • Your academic background includes a PhD in protein biochemistry with 3+ years therapeutic protein production experience, or MS with 7+ years, BS with 10+ years of therapeutic protein production experience
  • You have proven hands-on expertise in various protein characterization methods and tools including SDS-PAGE, WB, LAL, MCE, Analytical SEC and RP HPLC, MALS, DLS, DSF and mass spectrometryYou are an expert in protein purification using affinity, IEX, HIC and mixed-mode chromatography
  • You are capable of designing protein purification strategies and trouble-shooting problems independently
  • You have experience with generating high quality, difficult to-produce, low-expressing intracellular, membrane and/or secreted fusion proteins to enable antibody discovery and protein engineering
  • Your expertise in high throughput purification technologies would be a plus
  • You have excellent interpersonal, communication and presentation skills with the ability to mentor junior scientists as well as positively influence project direction and strategyYou take pride in being self-motivated and a creative problem solverYou have a point of view but are low ego
  • Design constructs and implement expression/purification processes to generate protein reagents at milligram to gram level scales
  • Collaborate extensively across functions and contribute to prioritization and planning within group and project teams to meet company goals
  • Accurately and clearly document experimental notes, protocols, and results
  • Support development of novel technologies, including high throughput capabilities, for protein production, analytical, and characterizations
  • Prepare to learn and grow in a highly productive, fun and collaborative environment!
  • Support development of state-of-art Protein Sciences platform for protein production and analytics
  • Lead efforts to develop protein production for novel antigens
  • Serve as a functional representative to collaborate within ADPE, project teams and other cross-functional groups

51-200 employees

Company mission
Alector is combining state-of-the-art antibody technology and recent discoveries in neuroimmunology and human genetics to develop novel.