Full-Time
Posted on 5/9/2026
Philanthropy funding basic biomedical research
$18.40 - $29.93/hr
Boston, MA, USA
In Person
| , |
Howard Hughes Medical Institute (HHMI) operates as an independent philanthropy that supports basic biomedical scientists and science educators. It funds people rather than specific projects, offering fellowships, grants, and resources to researchers and educators, and provides an adaptable work environment across fields like communications, finance, IT, investments, and law in addition to science. Its approach centers on funding talented individuals and enabling collaboration, rather than directing a single program. This helps scientists conduct experiments, explore ideas, and educate others with the aim of advancing biomedical knowledge and science education. Compared with other funders, HHMI emphasizes investing in people, fostering collaborative and results-driven work, and maintaining flexibility to support long-term impact. The overarching goal is to move science forward by expanding the potential of researchers and educators to make transformative contributions.
Company Size
1,001-5,000
Company Stage
Grant
Total Funding
$1M
Headquarters
Chevy Chase Village, Maryland
Founded
1953
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HHMI Investigator Karolin Luger wins 2026 Vilcek Prize. HHMI Investigator Karolin Luger is being honored by the Vilcek Foundation for her research into nucleosomes - the DNA-packaging structures inside cells - that has led to the development of innovative drugs for treating diseases, including cancer. The Vilcek Foundation has awarded HHMI Investigator Karolin Luger of the University of Colorado, Boulder, the $100,000 Vilcek Prize in Biomedical Scienceexternal link, opens in a new tab for her career-long dedication to the study of nucleosomes. Her pioneering research into these repetitive structures that package DNA inside the nucleus and regulate gene expression has contributed to the development of treatments for diseases such as cancer. Presented annually since 2006, the Vilcek Foundation Prizes in Biomedical Science honor immigrants who are leading advancements in biomedical research in the United States. Co-founder Jan Vilcek, whose groundbreaking work led to the development of the lifesaving drug Remicade(R), established the prizes to support distinct ingenuity in scientific inquiry. An HHMI Investigator since 2005, Luger has devoted her career to studying nucleosomes - repeating structures of DNA wrapped around proteins that make up chromatin, which form chromosomes. As a postdoc, Luger and Timothy Richmond at ETH Zürich captured a high-resolution image of chromatin, revealing the nucleosome structure in atomic detail for the first time. The discovery changed how researchers understand the interactions of proteins within the nucleosome, how they are modified, and how this controls gene activity. Many diseases have been found to stem from mutations in the nucleosome, resulting in the development of successful drug treatments, including cancer medicines. Luger continues to build on this original discovery in her labexternal link, opens in a new tab, where she and her team seek to understand the impact of chromatin architecture on genome-related processes. She is a member of the National Academy of Science and the American Academy of Arts & Sciences, and an associate member of EMBO.
Howard Hughes Medical Institute (HHMI) Investigator David R. Liu was awarded the 2025 Breakthrough Prize in Life Sciences for developing two gene-editing technologies - known as base editing and prime editing - which enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases.
Dennis McKearin joined HHMI as a Scientific Officer in 2008, and soon K-RITH became his primary focus.
HHMI announced the launch of the Freeman Hrabowski Scholars program in May 2022.
Loyola Marymount University was awarded a $2.5 million Driving Change grant in November 2022 from the Howard Hughes Medical Institute (HHMI) to create lasting culture change on research university campuses by creating a more inclusive learning environment.