Full-Time

Scientist – Medicinal Chemistry

Posted on 1/23/2025

Cytokinetics

Cytokinetics

501-1,000 employees

Develops drugs for muscle function disorders

Biotechnology
Healthcare

Compensation Overview

$128k - $156kAnnually

Junior, Mid

San Bruno, CA, USA

Category
Bioinformatics
Biology Lab & Research
Biology & Biotech
Required Skills
Data Analysis

You match the following Cytokinetics's candidate preferences

Employers are more likely to interview you if you match these preferences:

Degree
Experience
Requirements
  • Ph.D. in Chemistry required (BS/MS with generally 10+ years’ experience and demonstrated independent scientific creativity and contribution)
  • 0-5 years of relevant experience in synthetic organic/medicinal chemistry, preferably in lead optimization (familiarity with molecular and cellular biological techniques, especially screening techniques is a plus)
  • Proven track record of scientific achievement, problem solving, and impactful peer reviewed publications.
  • Demonstrated expertise in organic synthesis, chromatographic purification methods, and compound characterization using modern analytical techniques (NMR, MS, HPLC, etc.)
  • Organized, detail-oriented, excellent record-keeping skills, excellent verbal and written communication skills
  • Ability to work independently and perform well in a team environment
Responsibilities
  • Rapid synthesis of drug candidates to enable the advancement of optimization programs toward clinical development
  • Independently perform design and synthesis of next generation compounds by application of medicinal chemistry knowledge to the analysis of potency, and off-target selectivity data
  • Provide support, guidance, and mentorship for experiment design, data analysis, and result communication back to the team
  • Communication of research progress and data interpretation during project meetings
  • Maintain detail experimental records
Desired Qualifications
  • Familiarity with molecular and cellular biological techniques, especially screening techniques is a plus

Cytokinetics focuses on developing medicines that improve muscle function for patients with cardiovascular and neuromuscular diseases. Their products are small molecule drugs designed to either enhance or inhibit muscle function, tailored to specific therapeutic needs. The company has a pipeline of drugs, including omecamtiv mecarbil and reldesemtiv, which are in various stages of clinical trials. Unlike many competitors, Cytokinetics emphasizes rigorous scientific research and has conducted over 50 clinical trials to ensure the effectiveness of its treatments. The goal is to bring new therapies to market that address the unmet needs of patients suffering from conditions like heart failure, ALS, and HCM.

Company Stage

IPO

Total Funding

$58.4M

Headquarters

South San Francisco, California

Founded

1998

Growth & Insights
Headcount

6 month growth

-1%

1 year growth

-5%

2 year growth

-2%
Simplify Jobs

Simplify's Take

What believers are saying

  • Recent investments indicate strong interest in muscle activators and inhibitors.
  • Strategic partnerships, like with Sanofi, expand market reach and potential revenue.
  • Significant funding from Royalty Pharma supports commercial launch and R&D advancements.

What critics are saying

  • Increased competition could impact market share and profitability.
  • Potential delays in clinical trials could hinder drug commercialization.
  • Dependence on strategic partnerships may expose Cytokinetics to risks if challenges arise.

What makes Cytokinetics unique

  • Cytokinetics focuses on muscle activators and inhibitors for cardiovascular and neuromuscular diseases.
  • The company has a robust pipeline including omecamtiv mecarbil and aficamten.
  • Cytokinetics engages in strategic partnerships, like with Sanofi, to expand market reach.

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