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Full-Time

Research Associate III/Sr. Research Associate

Confirmed live in the last 24 hours

BridgeBio

BridgeBio

501-1,000 employees

Develops medicines for genetic diseases

Biotechnology
Healthcare

Compensation Overview

$105k - $115kAnnually

+ Performance Bonus + Equity + Health Benefits

Mid

San Bruno, CA, USA

Category
Computational Biology
Biology Lab & Research
Biology & Biotech
Requirements
  • BS/MS in a biology-related discipline
  • BS and >3 years, or MS and >2 year hands-on experience in a cell/molecular biology laboratory (oncology setting highly preferred)
  • Experience with oncology in vivo models: xenografts and syngeneic, tumor measurements, ex-vivo pharmacodynamics
  • Experience with mammalian cell culture, test article formulation, protein expression quantification (ELISA, MSD), qPCR, and western blot/immunoprecipitation
  • Experience with analyzing and presenting study results
  • Strong written and oral communication skills
Responsibilities
  • Execution of in vivo (tumor cell inoculations, dosing (po, sc, ip, iv), and blood sampling) and ex vivo pharmacology experiments (target and mechanism engagement) to assess the inhibition or activation of novel targets in the oncology setting
  • Assist in the planning and design of model development, PK/PD, tolerability, and efficacy studies using mostly (but not limited to) small molecule therapeutics
  • Graph, interpret, and communicate experimental data
  • Maintain records in written and electronic laboratory notebooks
  • Manage lab inventory and equipment
  • Understand and implement applicable regulations around animal care/safety/handling

BridgeBio Pharma develops medicines specifically for genetic diseases, focusing on conditions with well-understood genetic causes. The company operates using a decentralized subsidiary model, where each subsidiary concentrates on creating therapies for particular diseases while sharing central resources. This structure enhances efficiency and allows for the simultaneous advancement of multiple drug programs. BridgeBio utilizes advancements in genome sequencing and molecular biology to identify and develop effective treatments. Unlike many competitors, BridgeBio emphasizes independent thinking and transparency, enabling rapid, data-driven decision-making. The company's goal is to create significant therapeutic advancements by targeting diseases at their genetic source, ultimately bringing effective treatments to market more quickly.

Company Stage

IPO

Total Funding

$6.8B

Headquarters

Palo Alto, California

Founded

2014

Growth & Insights
Headcount

6 month growth

12%

1 year growth

45%

2 year growth

57%
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Simplify's Take

What believers are saying

  • Significant investments, such as the $46.84 million from Norges Bank and $200 million for the oncology spinout, indicate strong financial backing and growth potential.
  • The launch of BridgeBio Oncology Therapeutics with $200 million in funding highlights the company's commitment to advancing cancer treatments, particularly KRAS inhibitors.
  • Equity grants to new employees under the Amended and Restated 2019 Inducement Equity Plan demonstrate BridgeBio's commitment to attracting and retaining top talent.

What critics are saying

  • The competitive landscape in genetic disease therapies and oncology is intense, with numerous companies vying for market share.
  • The decentralized subsidiary model, while efficient, may lead to challenges in maintaining cohesive strategic direction and operational alignment.

What makes BridgeBio unique

  • BridgeBio's decentralized subsidiary model allows for focused and efficient drug development across multiple genetic diseases simultaneously, unlike traditional centralized biopharma companies.
  • The company's emphasis on genetic diseases with well-understood causes enables targeted and potentially more effective therapies, setting it apart from competitors with broader, less focused pipelines.
  • BridgeBio's robust pipeline of over 15 drug programs targeting 20 different genetic diseases showcases its diversified approach, reducing the traditional biopharma process timeline.