Full-Time

Senior Analyst

Information Security

Posted on 6/27/2025

Axsome Therapeutics Inc

Axsome Therapeutics Inc

501-1,000 employees

Biopharmaceutical company developing CNS therapies

Compensation Overview

$135k - $160k/yr

+ Annual Bonus + Equity

New York, NY, USA

Hybrid

On-site at NY HQ with a minimum of three days on-site per week; fully remote candidates not considered.

Category
IT & Security (4)
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Requirements
  • Bachelor’s degree in computer science, Information Security, or a related field.
  • Minimum of 5 years of experience in cybersecurity, with a focus on awareness training, alerts monitoring, threat hunting, liaison with MSP, incident response, and third party risk management
  • Experience working with cybersecurity frameworks (NIST CSF & RMF, ISO 27001), standards, and best practices (CIS, Mitre Att&ck)
  • Strong hands-on experience of networking, Microsoft 365 and Defender, Windows 10/11 OS
  • Working knowledge of networking and cloud infrastructure
Responsibilities
  • Monitor security alerts and events from various sources, including MSP, SIEM systems, IDS/IPS, and other security toolsets
  • Analyze and prioritize alerts to identify potential threats and vulnerabilities
  • Investigate and respond to security incidents in a timely manner
  • Manage the cybersecurity awareness training programs, promote security best practices and assess the effectiveness of training programs and make improvements as needed
  • Develop and deliver comprehensive cybersecurity awareness training programs
  • Create engaging InfoSec training materials and conduct regular trainings and evaluations to promote security best practices
  • Assess the effectiveness of training programs and make improvements as needed
  • Utilize advanced threat detection techniques and tools to uncover hidden threats and mitigate potential security threats
  • Collaborate with team members to develop and implement threat hunting strategies, appropriate mitigations and security controls improvement
  • Act as the point of contact for cybersecurity-related matters with Managed Service Providers (MSPs), ensure effective delivery of security services, and enforce adherence to SLAs
  • Review and assess MSPs’ performance against metrics and provide feedback for continuous improvement
  • Assist in coordinating incident response efforts, including identification, containment, eradication, and recovery
  • Maintain and improve dynamic incident response plans, guides and playbooks
  • Provide post-incident analysis and reporting to identify lessons learned and improve response processes
  • Perform regular vulnerability assessments and scans to identify security weaknesses
  • Prioritize and remediate vulnerabilities based on risk assessment and business impact
  • Collaborate with IT Infrastructure and Operations and Application Development teams to implement security patches and updates
  • Participate in security audits and contributing to the continuous improvement of security policies and procedures
  • Manage the Third-Party Risk Management Program
  • Support the InfoSec team with multiple, concurrent projects
  • Additional responsibilities as assigned by IT leadership
Desired Qualifications
  • Strong collaboration and negotiation skills, with a high degree of self-motivation, and ability to work independently with minimal supervision
  • Strong communication and interpersonal skills, with the ability to effectively collaborate with diverse teams
  • Relevant certifications such as Security+, CISSP, GIAC, CEH, CISA or equivalent are highly desirable
  • Proficiency in security tools and technologies such as SIEM, IDS/IPS, EDR, secure web gateway, patch management, training system, and vulnerability scanners
  • Excellent analytical and problem-solving skills with the ability to analyze complex security issues, identify root causes, and develop practical solutions
  • Commitment to staying informed about the latest security trends, threats, and technologies through ongoing learning and professional development activities
  • Ability to proactively plan, organize, deliver with limited oversight, prioritize, and quickly adapt to changing situations
  • Strong attention to detail and a meticulous approach to security-related tasks
Axsome Therapeutics Inc

Axsome Therapeutics Inc

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Axsome Therapeutics develops therapies for central nervous system (CNS) disorders and focuses on research, development, and commercialization of medicines. Its lead product candidate, AXS-05, is an oral NMDA receptor antagonist being developed to treat major depressive disorder (MDD) and treatment-resistant depression (TRD). The company moves its pipeline through clinical trials and regulatory approvals to bring therapies to patients and earns revenue from drug sales, partnerships, and licensing. It differentiates itself by pursuing CNS-focused therapies with NMDA receptor targets and by pursuing designations like FDA Breakthrough Therapy to speed development, with a goal of improving patient outcomes and quality of life.

Company Size

501-1,000

Company Stage

IPO

Headquarters

New York City, New York

Founded

2012

Simplify Jobs

Simplify's Take

What believers are saying

  • Auvelity Q1 2026 revenue hit $153.2M, up 59%, with $8B peak sales outlook post-Alzheimer's approval.
  • Total Q1 2026 revenue reached $191M, up 57%, beating estimates via sales force expansion.
  • Pipeline advances with AXS-12 NDA submission and AXS-20 addition for schizophrenia.

What critics are saying

  • Symbravo loses share to generic triptans and gepants due to high FDC pricing in 6-12 months.
  • AXS-12 NDA fails FDA approval from weak Phase III data, dropping stock 30-50% in 12-18 months.
  • Cash burns $305M reserves from sales force doubling before profitability in 18-24 months.

What makes Axsome Therapeutics Inc unique

  • Auvelity targets NMDA receptors for MDD and Alzheimer's agitation with FDA approvals.
  • Symbravo combines meloxicam-rizatriptan for acute migraine with long-term MOVEMENT trial benefits.
  • Sunosi treats narcolepsy daytime sleepiness with expanding Phase 3 indications.

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Benefits

Performance Bonus

Company Equity

Company News

Yahoo Finance
Apr 8th, 2026
Axsome Therapeutics surges 33% annually since 2015 IPO, eyes $16B peak sales

Axsome Therapeutics, a midcap biotech, has delivered a compound annual growth rate of 33.32% since its 2015 IPO, potentially turning a $50,000 investment into nearly $1 million. However, replicating this performance over the next decade would require the company to reach a market capitalisation of approximately $157 billion. The company's 2025 revenue grew 66% year over year to $638.5 million, driven primarily by Auvelity, a depression treatment. Auvelity may soon receive approval for treating agitation in Alzheimer's disease, expanding its addressable market to over five million US patients. Axsome Therapeutics' pipeline includes several phase 3 assets targeting over 150 million patients, with predicted peak sales exceeding $16 billion. Whilst the company shows promise for long-term growth through the 2040s, matching its historical performance remains unlikely.

Bitget
Mar 18th, 2026
Superstring Capital invests $6.84M in CNS pharma Axsome Therapeutics, stock up 27%

Superstring Capital Management invested $6.84 million in Axsome Therapeutics, purchasing 37,433 shares during Q4 2025, according to a SEC filing dated 17 February 2026. The investment represents nearly 4% of the fund's reported 13F assets. Axsome Therapeutics, a clinical-stage biopharmaceutical company, develops treatments for central nervous system conditions including major depressive disorder, migraines and narcolepsy. The company has commercialised several treatments and recently launched a Phase 3 trial for solriamfetol in major depressive disorder with excessive daytime sleepiness. Axsome shares traded at $158.40 on Wednesday, up 27% over the past year, outpacing the S&P 500's 19% gain. The company reported $638.5 million in annual revenue, a 66% increase from 2024, with a market capitalisation of $8.1 billion.

Yahoo Finance
Mar 18th, 2026
Superstring Capital bets $6.8M on CNS drugmaker Axsome as Phase 3 trial begins and shares climb 27%

Superstring Capital Management has disclosed a new $6.84 million position in Axsome Therapeutics, acquiring 37,433 shares during the fourth quarter of 2025. The stake represents nearly 4% of the fund's assets under management. Axsome Therapeutics, a biopharmaceutical company specialising in central nervous system disorder treatments, has seen its shares rise 27% over the past year to $158.40. The company generated $638.5 million in revenue over the trailing twelve months, representing 66% growth from 2024. The company markets therapies for depression, migraine and sleep disorders whilst advancing a late-stage pipeline. Axsome recently initiated a Phase 3 trial for solriamfetol targeting major depressive disorder with excessive daytime sleepiness, a segment with no approved treatments currently available.

Yahoo Finance
Mar 12th, 2026
Axsome's Auvelity surpasses $500M revenue, eyes approval for Alzheimer's agitation by April

Axsome Therapeutics reported Auvelity surpassed $500 million in revenue during its third year, with total company sales approaching $640 million in 2025. Auvelity posted approximately 68% year-over-year growth. The company's supplemental NDA for AXS-05 (Auvelity) in Alzheimer's disease agitation is under priority review, with a PDUFA date of 30 April 2026. This represents Axsome's key near-term regulatory catalyst, supported by three positive trials. Axsome is doubling its field force from 300 to 600 representatives by Q2, ahead of a potential launch. The company is advancing seven Phase III trials across multiple indications whilst maintaining approximately $323 million in cash to fund operations.

Yahoo Finance
Mar 6th, 2026
Axsome doubles salesforce to 600 reps as AUVELITY hits $155M quarter ahead of April Alzheimer's decision

Axsome Therapeutics reported $155 million in quarterly revenue for AUVELITY, annualising over $600 million just 13 quarters post-launch, though market penetration remains at approximately 0.2% of the antidepressant market. The company plans to double its salesforce from 300 to 600 representatives to drive uptake and support a potential Alzheimer's agitation launch. Over 50% of AUVELITY prescriptions are now monotherapy, with roughly 15% first-line and 35% first-switch therapy. Primary care clinicians account for about 30% of prescribers. Axsome's supplemental NDA for AXS-05 in Alzheimer's disease agitation is under priority review with an FDA decision expected on 30 April. Management reported revenue growth outpacing operating expenses by 3-to-1 in 2025, demonstrating strong operating leverage despite increased direct-to-consumer spending.

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