Full-Time
Director – Systems Biology
AI-driven precision medicine through clinical and molecular data analysis
Senior
Chicago, IL, USA
- 3+ years experience in industry or academia, following completion of PhD degree in quantitative discipline (e.g. statistical genetics, cancer genetics, bioinformatics, computational biology, or similar). Alternatively, a PhD in molecular biology with a very strong record of high-throughput sequencing data analysis or equivalent practical experience
- Strong understanding of the molecular nature of human disease
- Demonstrated expertise with integrative modeling of clinical and/or omics datasets to derive new biological insight
- Experience working with large transcriptome data sets
- Experience modeling clinicopathological and patient outcome data
- Experience managing and mentoring multiple direct reports and supporting junior scientists
- Experience managing multiple cross-functional projects, and delivering results in a timely and professional manner
- Thrive in a fast-paced environment and willing to shift priorities seamlessly
- Lead team responsible for state-of-the-art analysis and modeling of multimodal clinical and genomic data
- Evaluate and implement emerging technologies and methods in genomic medicine
- Coordinate with leads in Research, Engineering, Data Science, and Medical Affairs to develop and deliver innovative computational solutions and analytical support
- Support business units in development and execution of biomedical studies
- Design and execute validation plans for compliance with CAP/CLIA regulations for newly developed assays or algorithms
- Develop novel biomarkers of response and resistance to therapies
- Support development of companion diagnostics
- Document, summarize, and communicate highly technical results and methods clearly to non-technical audiences
- Author whitepapers and peer reviewed manuscripts illustrating the value of multimodal analysis for advancing precision medicine
- Strong peer-reviewed publication record
- Experience working with real world evidence clinical cancer data (progression free vs overall survival, clinical trial design, data imputation and managing missing variable bias, etc)
- Understanding of CLIA/CAP validation protocols and how to bring scientific ideas to market
- Strong programming experience in R or Python
- Strong database and SQL skills
- Experience with engineering practices for research computing (docker, git, code review, linux, cloud computing)
Tempus Labs, Inc. is a leader in precision medicine, leveraging artificial intelligence to analyze vast clinical and molecular data, enabling physicians to deliver personalized, data-driven care. The company's advanced machine learning platform and unique solution sets facilitate the discovery, development, and delivery of optimized therapeutic options for patients. With a focus on extensive molecular profiling, Tempus has developed a robust pan-cancer tumor organoid platform and validated a liquid biopsy assay, demonstrating their commitment to transforming personalized patient care and their position at the forefront of the healthcare industry.
Company Stage
Series G
Total Funding
$1.3B
Headquarters
Chicago, Illinois
Founded
2015