Biotechnician 1

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

The Biotechnician I position will directly support the startup phase of the Hopewell manufacturing facility and then shift focus to hands-on execution and support of cGMP manufacturing operations.

Facility Start-Up: Focused on related activities required to design, build, commission, and license BeOne’s first biopharmaceutical plant in the United States.

Essential Functions of the Job: include but not limited to:

• Design review

• Equipment selection, procurement and testing

• Protocol development and execution

• Acceptance testing and equipment/automation debugging

• Technical training

Hands-On cGMP Operations: Focused on execution of cGMP manufacturing activities required to deliver the production plan reliably and compliantly.   

• Follow cGMP procedures to support manufacturing execution and automated recipes

• Media preparation & transfers / filtration

• Cell culture sampling, monitoring & transferring

• Harvest operations

• Buffer preparation & transfers / filtration

• Operational and cleaning of chromatography and filtration systems.

• Equipment & process troubleshooting

• Deviation identification, reporting, drafting, investigate closure

• Change control drafting, presenting, closure

• cGMP procedure development and optimization

• Requesting, staging, and verifying materials for production activities

• Setup and preparation of equipment for formulation and filling

• Final filtration and formulation of drug product

• Aseptic filling of vials inside a Grade A isolator using automated filling equipment

• Performing in-process visual inspection for quality assurance

• Labeling and packaging of finished drug product in compliance with cGMP

• Completing batch documentation and reviewing records for accuracy

• Supporting routine cleanroom operations, equipment sanitization, and environmental monitoring

• Assisting in deviation investigations and participating in CAPA implementation as needed

• Operation of Distributed Computer System (DSC)

• Operation of equipment’s such as Clean-in-Place (CIP), Steam-in-Place (SIP) skid, Caustic skid, autoclave, part washer, filter integrity tester, biowelders, etc.

• Operation of SoloVPE protein concentration analyzer

• Cleaning of the facility

• Collection of samples for environmental monitoring

• Removal of process waste

Leadership Skills:

• Support supervisor managing day to day activities, including staff availability and task load

• Self-directed leadership within both predicable and ambiguous work environments

• Thoughtfully escalates issues/concerns in a timely manner as appropriate

Education and Experience:

• High school education or GED required.

• AS/BS/BA in science related field, biopharmaceutical or equivalent technical experience preferred.

• Evidence of good verbal and written communication.

• Ability to work in fast paced dynamic environment with competing priorities.

• Demonstrated ability to collaborate within and between diverse groups.

• Proactive identification and implementation of continuous improvement opportunities.

• Aptitude for learning moderately complex technical systems.

• Able to receive and incorporate feedback – passion for ongoing professional development a plus.

Computer Skills:   Familiarity with computer-based systems.  Word, Excel, and PowerPoint a must.

Physical Requirements:

• Must be able to stand for long periods, up to 8 to 10 hours/day.

• Must be able to reach above shoulder level, bend/stoop, push/pull, and handle/grip frequently.

• Must be able to work scheduled 40 hours with the ability to work overtime as needed.

• Must be comfortable in working in varying temperatures.

• Frequent lifting, pushing, pulling, and carrying.  Ability to lift to 40 lbs.

• Regular reaching, bending, stooping, and twisting.

• Repetitive motion and substantial movement of the wrists, hands, and/or fingers.

• Environment requires dedicated gowns, depending on area.

• Work with hazardous materials and chemicals.

• Willing to work any shift.

Travel: International and domestic as required

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process.  Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [email protected].