AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.
We are looking for a Lead Manufacturing BioProcess Technician to be a key member of the clinical manufacturing team responsible for design, construction, qualification, and operation of a new GMP manufacturing facility for the production of antibody therapeutics. In this role, based in beautiful Vancouver, Canada, you will be responsible for helping to build critical processes, training and an exceptional team.
How you might spend your days
- Working cross functionally with multiple teams including MSAT, Process Development, QA/QC, and Engineering to build all required elements of an advanced bioprocessing facility to deliver the next generation of therapeutic antibodies.
- Leading and mentoring team members for Manufacturing Operations
- Designing and operating manufacturing systems and processes that are technically sound, promote effective and efficient operations, and comply with cGMP requirements
- Ensuring the schedules of the people, facility, equipment, materials, and documents are established and maintained to support the capacity/throughput of the manufacturing process
- Supporting manufacturing processes such as, but not limited to, cell line initiation (vial thaw), cell line scale-up, bioreactor operations, harvest clarification, TFF, column packing, chromatography, bulk drug substance fill, media and buffer preparation, weigh and dispense operations & drug product filling
- Helping lead equipment FAT, SAT, and facility start-up as needed
- Helping author and revise cGMP documentation (batch records, protocols, SOPs) and Perform periodic review of cGMP documentation to ensure accuracy
- Supporting or leading investigations related to the manufacturing process. Author deviations, non-conformances, and CAPAs as required; as well as identify, lead, and implement continuous improvement projects
- Driving process improvements and efficiency initiatives applying lean methodology such as standard work, Kaizen, Kanban, 5S, value stream mapping, root cause analysis, etc.
- Contributing and assisting with corporate, FDA, Health Canada and other regulatory bodies during facility audits
We’d love to hear from you if you
- Have an AS/BS/BA in Biological Sciences, Physical Sciences, or Engineering or combination of college coursework and related work experience or a biotech certificate from approved program
- Have 5 years of GMP manufacturing experience
- Have knowledge of upstream and/or downstream processing techniques
- Have experience in creation and revision of SOPs and Manufacturing Batch Records
- Have experience ensuring timely execution and review of procedures, batch documentation, logbooks, deviations, CAPAs, change controls, and completion of ERP orders
- Are passionate about building and implementing a "Right First Time" culture to meet cGMP requirements for clinical material
- Are enthusiastic about applying your expertise in manufacturing operations and are excited to create a lasting legacy our industry
What we offer
AbCellera’s hiring range for this role is CAD $72,600 - $90,700 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.
About AbCellera
AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.
And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.
We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.
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