Manager – Statistical Programming
Confirmed live in the last 24 hours
Arrowhead Pharmaceuticals

201-500 employees

RNAi-based gene-silencing therapeutics
Company Overview
Arrowhead Pharmaceuticals stands out in the biopharmaceutical industry through its focused application of RNA interference (RNAi) mechanisms to develop targeted therapies for genetic diseases, exemplified by its candidate plozasiran aimed at reducing ApoC3 protein levels to manage severe hypertriglyceridemia. The company's proprietary TRiM platform demonstrates a competitive edge by enabling tissue-specific gene silencing, which has shown promise in early clinical trials, such as the AROAPOC3-2001 study, to improve lipid levels safely and effectively. Arrowhead's approach to drug development not only streamlines manufacturing and potentially reduces costs but also positions the company as a leader in RNAi therapeutics, with ongoing research that could transform treatment paradigms for patients with lipid disorders.
Biotechnology

Company Stage

N/A

Total Funding

$899.9M

Founded

2004

Headquarters

Pasadena, California

Growth & Insights
Headcount

6 month growth

10%

1 year growth

32%

2 year growth

63%
Locations
Pasadena, CA, USA • San Diego, CA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
Desired Skills
SAP Products
CategoriesNew
Backend Engineering
Software QA & Testing
Software Engineering
Requirements
  • Master's degree in biostatistics/statistics/public health or similar field
  • At least 3 years' experience of statistical programming for clinical trials
  • Proficiency in SAS, including complex data manipulation, basic analysis procedures, SAS/MACRO, and SAS/GRAPH
  • Interest in career development as a leading role in statistical programming in pharmaceutical industry
  • Excellent verbal and written communication skills
Responsibilities
  • Develop targeted, study-specific SDTM and ADaM dataset checks
  • Perform independent QC, from raw data to ADaM, of primary and key secondary endpoints
  • Create draft output shells for ad-hoc requests, prepare analysis specs and scope
  • Deliver programming results for ad-hoc analysis requests
  • Review outputs provided by CROs for accuracy and consistency with the analysis plan and specs
  • Review and contribute to the development of study SAP
  • Collaborate with data management and their programming team to ensure appropriate data collection and reporting
  • Participate in study team meeting and support statistician operational activities
  • Assist in efforts to identify, develop, and implement departmental standards, applications, processes and training
  • Develop and manage the statistical programming team
  • Develop or support standard operation procedure preparation