Full-Time

Senior Director

Clinical Science Liaisons

Posted on 10/11/2024

Pliant Therapeutics

Pliant Therapeutics

51-200 employees

Develops treatments for fibrotic diseases

Biotechnology
Healthcare

Compensation Overview

$280k - $290kAnnually

Senior

San Bruno, CA, USA

Field-based or local position in South San Francisco.

Category
Healthcare Administration & Support
Physicians & Surgeons
Medical, Clinical & Veterinary
Required Skills
Word/Pages/Docs
Excel/Numbers/Sheets
Requirements
  • Advanced degree or equivalent (e.g., PA/MPH/DO/MD/PharmD/PhD) with approximately 3-4 years of clinical trial and/or R&D experience, including 12+ years in a CTL, CSL, MSL, or comparable position
  • 8+ years of experience managing direct reports, demonstrating effective teamwork, proven leadership, and hands-on coaching and management.
  • Ability to travel domestically and internationally up to 30%, including travel to South San Francisco headquarters at least 6 times/year and for key departmental and/or company meetings, as needed
  • Working knowledge of protocol and clinical drug development processes, clinical study design, study planning and management, and monitoring data
  • Track record of demonstrating solid 'leadership behaviors'
  • Well-developed interpersonal and people-management skills, as well as effective communication
  • High attention to detail and the capability to understand the 'overarching' perspective
  • Established capacity to define priorities and manage several demands simultaneously
  • Ability to analyze critically and practice resourcefulness and initiative
  • Ability to work independently while demonstrating initiative, adaptability, and adept judgment
  • Comfortable working at all levels of the organization, including senior stakeholders
  • Demonstrated proficiency in Microsoft Word, PowerPoint, and Excel
  • Ability to demonstrate Pliant’s values
Responsibilities
  • Serve as a people leader for the global clinical science liaison team, training and empowering the team to co-develop, manage, and implement strategic plans to support clinical trial education, recruitment, enrollment, and retention.
  • Provide global functional leadership, creating effective processes and engagement plans that are customized as needed for global regions and delegating team tasks as applicable.
  • Lead budget review, negotiation, and payment approvals for functional service provision of CSLs supporting Pliant’s development portfolio.
  • Develop training materials and instructions to support CSL team actions and responsibilities.
  • Develop clinical site engagement communications and presentations for site initiation, office visits, investigator meetings, advisory boards to enhance current and future clinical trial awareness.
  • Identify and communicate key clinical trial issues and insights to the VP, Clinical Operations, and any other appropriate functional stakeholders to help influence clinical trial execution including, but not limited to, site identification, site start-up, patient screening and recruitment, and patient retention.
  • Oversee and drive the CSLs’ education, analysis, and resolution of issues with clinical study sites and investigators to support efforts to improve recruitment and activation timelines.
  • Collaborate with Development Operations, Clinical Development, and external stakeholders to support clinical needs and monitor study performance and progress.
  • Facilitate identification of clinical trial site and community educational needs for Pliant clinical trials.
  • Attends scientific and medical congresses, and professional conferences.
  • Participate in Pliant community outreach and engagement activities.
  • Maintain business and clinical knowledge of the treatment landscape including current treatment strategies, current and pending competitors, and new therapeutic developments.

Pliant Therapeutics develops treatments for fibrotic diseases, which cause thickening and scarring of connective tissue, leading to organ dysfunction. Their products work by targeting the biological mechanisms behind fibrosis, particularly through the inhibition of integrins, proteins that help cells stick together and communicate. This focus allows Pliant to create specific and effective therapies for various fibrotic conditions. Unlike many competitors, Pliant emphasizes a deep understanding of fibrosis and integrin biology, which informs their drug development process. The company's goal is to halt the progression of fibrotic diseases and restore normal organ function, ultimately improving the lives of patients affected by these conditions.

Company Stage

IPO

Total Funding

$201.4M

Headquarters

San Francisco, California

Founded

2015

Growth & Insights
Headcount

6 month growth

0%

1 year growth

7%

2 year growth

47%
Simplify Jobs

Simplify's Take

What believers are saying

  • Positive Phase 2a trial data for bexotegrast in PSC boosts Pliant's clinical credibility.
  • Orphan Drug Designation for PLN-74809 in IPF and PSC offers regulatory advantages.
  • Advancements in precision medicine enhance efficacy of Pliant's targeted drug candidates.

What critics are saying

  • Intensifying competition in IPF treatments may impact Pliant's market share.
  • FDA scrutiny on fibrosis drugs could delay Pliant's approval timelines.
  • Geopolitical tensions may disrupt global clinical trial operations for Pliant.

What makes Pliant Therapeutics unique

  • Pliant focuses on integrin-targeting therapies for fibrotic diseases, a unique approach.
  • PLN-74809 is a dual selective inhibitor for IPF and PSC, showing innovation.
  • Partnership with Novartis for PLN-1474 highlights strategic collaboration in liver fibrosis.

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