Full-Time
Vice President
Market Access
Updated on 9/3/2026
Mirum Pharmaceuticals
201-500 employees
ASBT inhibitors for rare liver diseases
Compensation Overview
$350k - $375k/yr
Foster City, CA, USA
Hybrid
Hybrid schedule indicated by the posting.
Bachelor's, Master's, MBA, PharmD
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- A bachelor's degree is required; equivalent experience may be considered.
- A minimum of 18 years of progressive leadership experience within the pharmaceutical or biotechnology industry is required.
- A minimum of 10 years leading Market Access organizations, including significant responsibility for Pricing and Contracting, National and Regional Payer Accounts, Government Programs, Field Reimbursement, and Health Economics and Outcomes Research, is required.
- Demonstrated success developing and executing market access strategies for specialty or rare disease products across pharmacy and medical benefits is required.
- Experience leading market access planning for pipeline assets through commercialization and product launch is required.
- Demonstrated experience leading commercial organizations through periods of growth and organizational evolution is required.
- Established executive-level relationships with national and regional payer organizations are required.
- Proven executive leadership with a track record of building, developing, and retaining high-performing teams is required.
- Strong strategic leadership balanced with operational execution and attention to detail is required.
- Executive presence with the ability to influence senior leadership, cross-functional stakeholders, and external customers is required.
- Excellent financial acumen, including experience managing pricing strategy, gross-to-net performance, contracting economics, and departmental budgets, is required.
- Strong analytical capabilities with the ability to synthesize complex market, reimbursement, and financial information into actionable business strategies are required.
- Demonstrated ability to lead through ambiguity, organizational change, and evolving market conditions is required.
- Experience prioritizing competing business needs while making timely, data-driven decisions is required.
- Proven ability to anticipate business challenges, develop innovative solutions, and execute effectively is required.
- Strong collaboration skills with experience leading highly matrixed, cross-functional organizations are required.
- High integrity and commitment to ethical leadership and compliance are required.
- Develop and execute the North American Market Access strategy across marketed products and pipeline assets.
- Serve as the executive leader responsible for maximizing patient access while achieving net revenue, reimbursement, and profitability objectives.
- Provide strategic counsel to the Executive Leadership Team on payer dynamics, pricing strategy, reimbursement trends, healthcare policy, and competitive market developments.
- Lead market access planning for pipeline products, lifecycle management initiatives, label expansions, and commercial launch readiness.
- Own enterprise pricing strategy, gross-to-net optimization, contracting strategy, and reimbursement economics across commercial and government channels.
- Oversee compliant commercial pricing, government price reporting, rebate administration, and associated financial obligations.
- Establish annual pricing governance and contracting strategies that optimize market access and corporate financial objectives.
- Lead payer contracting strategies to balance coverage objectives, reimbursement quality, and net price performance.
- Lead national and regional payer account strategies across Commercial, Medicare, Medicaid, and other government programs.
- Provide leadership to field-based payer account and field reimbursement organizations.
- Partner with Medical Affairs, Biostatistics, and Global Market Access to establish evidence generation priorities, HEOR strategy, and payer evidence plans.
- Ensure timely development and submission of United States and Canadian payer dossiers.
- Develop external communication strategies supporting reimbursement, label expansions, future indications, and pipeline products.
- Monitor federal and state healthcare policy, including Medicare, Medicaid, 340B, the Inflation Reduction Act, and reimbursement changes.
- Represent the company with payer organizations, industry associations, and other external stakeholders.
- Collaborate with Commercial, Medical Affairs, Regulatory, Finance, Legal, Commercial Operations, Supply Chain, and Global teams to integrate market access strategy throughout product development and commercialization.
- Provide enterprise subject matter expertise across pharmacy and medical benefit design, reimbursement policy, healthcare economics, and market access trends.
- Build, develop, and lead a high-performing Market Access organization through talent development, coaching, succession planning, and organizational design.
- Ensure team activities comply with applicable laws, regulations, and company policies.
- Manage departmental budgets and resources while maintaining fiscal responsibility.
- Deliver key performance objectives within established timelines and budget.
- An advanced degree such as an MBA, PharmD, MPH, MS, or equivalent is preferred.
- Experience working across both United States and international market access environments is preferred.
- Experience within rare disease and specialty pharmaceuticals is strongly preferred.
- Strong communication, negotiation, and presentation skills with the ability to drive alignment and consensus are desirable.
Mirum Pharmaceuticals develops and commercializes therapies for rare liver diseases. Its lead drug LIVMARLI (maralixibat) is an oral ASBT inhibitor that lowers bile acid buildup to relieve itching in cholestatic conditions such as Alagille syndrome, and the company is pursuing LIVMARLI for additional rare liver diseases, with volixibat as another ASBT inhibitor in its pipeline. The company differentiates itself by focusing on rare pediatric and adult cholestatic diseases and building dedicated commercialization infrastructure in the U.S. and other major markets, including partnerships with physicians, payers, and patient groups to improve patient access. Mirum’s goal is to bring effective therapies to patients with rare bile-duct and liver disorders, expand LIVMARLI indications, and establish a sustainable market presence in key markets.
Company Size
201-500
Company Stage
IPO
Headquarters
Foster City, California
Founded
2018
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Simplify's Take
What believers are saying
- Q2 2026 net product sales reached $176.2 million, and guidance rose to $700 million.
- Rob Myers starts September 21, 2026, strengthening hepatology leadership before key readouts.
- Volixibat, brelovitug, and zilurgisertib create multiple catalysts through first-half 2027.
What critics are saying
- FDA recommended another volixibat Phase 3 on August 5, 2026, delaying PSC filing.
- If LIVMARLI growth slows, Mirum loses the cash engine funding its pipeline.
- Zilurgisertib’s September 26, 2026 PDUFA denial would crush sentiment and financing flexibility.
What makes Mirum Pharmaceuticals unique
- LIVMARLI dominates rare pediatric cholestatic disease with expanding PFIC and biliary atresia labels.
- Mirum combines commercialization strength with late-stage hepatology pipeline breadth across PSC, HDV, and FOP.
- Exclusive zilurgisertib rights from Incyte add a near-term rare-disease launch platform.
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Benefits
Hybrid Work Options
Growth & Insights and Company News
6 month growth
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↑ 0%Mirum Pharmaceuticals has appointed Dr Rob Myers as chief medical officer, effective 21 September 2026. Dr Myers will lead the company's global medical and clinical development functions. Dr Myers brings over 20 years of experience in drug development, with particular expertise in hepatology. He joins from OrsoBio, where he served as chief medical officer and head of development. Previously, he held senior leadership positions at Gilead Sciences, overseeing clinical development programmes across liver fibrosis, cholestatic liver diseases, and gastrointestinal inflammation. Dr Myers has published more than 200 peer-reviewed papers and has contributed to advancing understanding of primary sclerosing cholangitis. He holds an MD from Western University and a master's degree in epidemiology from the University of Calgary.
US FDA approves Regeneron's rare bone disorder drug. Regeneron's Pasatru has received US FDA approval for adults with FOP after clinical trials showed a significant reduction in abnormal bone formation. By Reuters August 20, 2026, 8:59:40 AM IST (Published) The US FDA on Wednesday (August 19) approved Regeneron's drug for a rare genetic disorder after it significantly reduced abnormal bone formation in certain soft tissues. New York-based Regeneron's shares rose 4%. The drug, garetosmab, branded as Pasatru, was approved to treat adults with fibrodysplasia ossificans progressiva (FOP) - a condition in which muscle, tendon and ligament tissue gradually turns into bone, leading to a "second skeleton" that causes progressive loss of mobility and reduced life expectancy. In a 56-week trial involving 63 participants, Pasatru reduced the development of new bone abnormalities by 94% in patients treated with a 3 mg per kg dose and by 90% in those given a 10 mg per kg dose, compared with a placebo. The drug works by blocking Activin A, a protein involved in triggering abnormal bone growth in patients with FOP. Susan Rhee, a member of Regeneron's clinical team, told Reuters last week that the company plans to start a trial for children later this year. The drug will compete with French drugmaker Ipsen's oral treatment Sohonos, which in 2023 became the only other treatment approved by the US Food and Drug Administration. Incyte and partner Mirum Pharma, as well as privately held Ashibio, are also developing treatments for the condition. In 2020, Regeneron paused dosing in a mid-stage trial of the drug after five patient deaths, ultimately discontinuing the study and working with global regulators to design the late-stage trial, according to the company. The condition affects roughly 1 in 2 million people worldwide, with around 800 to 900 active diagnosed cases globally, according to data from the National Institutes of Health.
Mirum Pharmaceuticals shares plunged 15% on Thursday after the FDA recommended an additional Phase 3 study for its liver disease candidate Volixibat, potentially delaying the new drug application until the first half of 2027. Citizens lowered its price target to $137 from $146 whilst maintaining an Outperform rating. The regulatory setback overshadowed strong second-quarter results. Mirum reported revenue of $176.2 million, beating analysts' estimates of $167.3 million. The company raised its full-year net product sales guidance to $680 million to $700 million, from $660 million to $680 million. Mirum ended the quarter with $561.3 million in cash and equivalents. Volixibat has already received FDA Breakthrough Therapy and Orphan Drug designations.
Mirum Pharmaceuticals raised its full-year 2026 net product sales guidance to $680 million to $700 million, citing growth in Alagille syndrome and expanding adult PFIC diagnosis. The company secured $690 million through a convertible note offering, improving its capital structure whilst settling 75% of 2029 notes. The firm identified a significant opportunity in adult PFIC, estimating at least 2,000 addressable patients each in the US and Europe. Commercial operations achieved a high-50s percent cash contribution margin, representing a 5 percentage point year-over-year improvement. Mirum delayed its volixibat PSC NDA submission due to alignment issues with FDA reviewers but received Breakthrough Therapy Designation. The company targets a first-half 2027 NDA submission for PSC and anticipates Phase III PBC results in Q1 2027.
Mirum Pharmaceuticals reported revenue of $176.24 million for the quarter ended June 2026, up 37.9% year-over-year. The figure exceeded the consensus estimate of $164.76 million by 6.97%. The company posted a loss of $0.80 per share, compared to $0.12 a year ago, slightly missing the estimated loss of $0.77 per share. Product sales showed strong performance across categories. Livmarli generated $128.72 million, surpassing the $119.6 million analyst estimate. Bile acid medicines brought in $47.52 million, also beating expectations of $45.64 million. Despite beating revenue estimates, Mirum's shares fell 18.7% over the past month, underperforming the S&P 500's 3.5% gain.