Full-Time

Scientist

Posted on 10/22/2024

Axle

Axle

201-500 employees

Provides informatics solutions for biomedical research

Enterprise Software
Biotechnology
Healthcare

Compensation Overview

$75k - $83kAnnually

Mid

Bethesda, MD, USA

Category
Lab & Research
Life Sciences
Physical Sciences
Required Skills
Data Analysis
PowerPoint/Keynote/Slides
Requirements
  • Masters
  • Good Manufacturing Practice (GMP)
  • Chemistry
  • Powerpoint
  • MS Project
  • Outlook
  • Excel
  • Word
  • Microscopy: Confocal, Electron, Multi-Photon, Fluorescence, Super-Resolution
  • Nuclear Magnetic Resonance
  • Thin-layer chromatography
  • X-Ray Crystallography
  • Manuscript writing
  • Mass Spectrometry
  • Spectrophotometry
  • Thermal analytical technologies
  • Chromatography technologies (HPLC, UPLC, GC, IC)
  • Kilo Lab or pilot plant experience
Responsibilities
  • Upon request, the contractor shall provide documentation evidence of any and/or all work products, including, but not limited to, the following tasks:
  • 1) Work on products and documents related to scaling up and synthesizing APIs and intermediates; design and develop scalable synthetic routes; optimize synthetic steps; isolate and identify impurities.
  • 2) Work on products and documents related to producing research reports; generate reports to support technology transfer to CROs; conduct and write literature reviews; search chemical databases for journal articles, patents and related technologies; publish and present relevant projects.
  • 3) Work products and documents related to collaboration with the technology transfer office and external patent offices to provide the necessary information for filing patents in selected programs. - Quarterly
  • Clean Equipment - Weekly
  • Meet with lab members to present updates - Monthly
  • Perform synthetic route scouting
  • Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
  • Maintain up-to-date electronic laboratory notebook detailing all experiments.
  • Gather, analyze and interpret data; prepare summaries and reports.
  • Search chemical databases for journal articles, patents and related technologies.
  • Provides laboratory experience needed to assist in performing various chemical experiments and procedures.
  • Perform chemical and biochemical reactions and appropriate analytical analyses.
  • Perform analytical validation and testing of compositions.
  • Utilizes and operates various complex laboratory machines and equipment.
  • Perform general maintenance and upkeep of equipment and instrumentation.
  • Troubleshoot and provide routine maintenance of the instruments and equipment.
  • Monitor, troubleshoot and initiate or take corrective action to maintain instrument function and quality.
  • Identify the cause of common problems and mistakes and make necessary repairs.
  • Documents and analyzes results, produces detailed summaries and reports.
  • Write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals.
  • Collect and review data; analyze and interpret data and results.
  • Produce research reports and communicate results.
  • Analyzes organic and inorganic compounds to determine chemical and physical properties, composition, structure, relationships between compounds, and reactions.
  • Formulate chemistry plans for the development of soluble, potent, selective small molecule probes of biological function.
  • Analyze samples using validated analytical methods for ongoing studies.
  • Perform the total syntheses of target compounds.
  • Manage bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
  • Perform chemical synthesis and optimization of small molecule probes for use in biological research.
  • Perform organic synthesis of key materials (e.g., reference compounds and precursors for labeling).
  • Perform organic synthesis in support of the medicinal chemistry program.
  • Perform solid state analysis of target compounds
  • Adds heat, light, energy or a catalyst to show changes in composition.
  • Purify compounds by preparative chromatography from chemists.
  • Provides laboratory experience needed to perform various complex chemical experiments and procedures.
  • Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
  • Perform analytical validation and testing of compositions.
  • Prepares test solutions, compounds, and reagents and maintains necessary laboratory supplies.
  • Prepare reagents and maintain an active inventory of all chemicals kept in the laboratory.
  • Keep an active inventory of all chemicals kept in the laboratory.
  • Schedules, tracks and reports analyses of experiments and procedures.
  • Perform analytical validation and testing of compositions and report results.
  • Maintain computer database for various records.
  • Independently provides laboratory experience needed to perform various complex chemical experiments and procedures.
  • Perform bulk-synthesis, purification and formulation efforts for advanced testing in animal models.
  • Develop new analytical and separation techniques for the solution of scientific questions.
  • Perform analytical validation and testing of compositions.
  • Designs and optimizes chemical experiments and procedures.
  • Develop and document new procedures.
  • Develop novel chemistry methodologies and technologies that advance the field and make recommendations.
  • Collaborate with staff to evaluate and/or develop new techniques.
  • Develop and present plans for novel syntheses and approaches to new compounds.
  • Develop experimental procedures and research protocols.
  • Develop and present plans for novel syntheses and approaches to new compounds.
  • Carry out scale-up of the chemical probes of interest for additional studies.
  • Trains staff on new experiments and practices, operations and maintenance of instruments and equipment, safety practices, etc.
  • Maintain and perform training on scientific instrumentation and equipment.
  • Work with staff on all mandatory training and competency assessments.
  • Coordinate safety training (e.g., CPR and fire extinguisher use).
  • Work with facilities manager on evacuation procedures and drills.

Axle Informatics provides specialized solutions that combine bioscience and information technology, focusing on translational research, health informatics, and data science. Their products help research centers and healthcare organizations turn scientific discoveries into practical applications, such as new treatments or diagnostics. Axle develops research tools that enhance decision-making by utilizing advanced analytical models, algorithms, and visualization tools to manage large volumes of data. This automation allows researchers to efficiently track and analyze data, leading to improved healthcare outcomes. Unlike many competitors, Axle emphasizes customized software and data management platforms that facilitate the transition from laboratory research to clinical application, known as moving from "bench to bedside." The company's goal is to advance public health by providing effective informatics solutions that support biomedical and clinical research.

Company Stage

N/A

Total Funding

N/A

Headquarters

Rockville, Maryland

Founded

2002

Simplify Jobs

Simplify's Take

What believers are saying

  • Rising demand for AI-driven data analytics boosts Axle's healthcare partnerships.
  • Precision medicine's growth aligns with Axle's computational biology expertise.
  • Global health informatics market growth enhances Axle's competitive edge.

What critics are saying

  • Increased competition from companies like Indica Labs may reduce market share.
  • Rapid digital pathology advancements require significant R&D investment to stay competitive.
  • Dependence on partnerships for large contracts poses risks if partnerships dissolve.

What makes Axle unique

  • Axle Informatics specializes in bioscience and IT, focusing on translational research.
  • The company offers advanced solutions in health informatics and data science.
  • Axle leverages expertise in biomedical science and software engineering for research tools.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

Paid Vacation

Paid Holidays

401(k) Company Match

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

INACTIVE