Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Fall 2023 semester with interest in nucleic acid R&D to join the process chemistry team. The candidate will be involved in day-to-day routine laboratory activities for supporting in-process analytics including UV measurement, UPLC and LC-MS analysis, integration for UPLC chromatograms of various stages in-process guide RNA samples. The candidate will learn a variety of in-process analytics quickly, will generate data and document them in the Prime’s project specific folder, and will share results at scientific team meetings.

We want curious problem solvers who enjoy working on exciting projects, working within a team and are passionate about developing genetic editing technologies to better human health and well-being.

Primary Responsibilities: 

• Supports in-process analytics for Prime’s long guide RNA (ribonucleic acid) platform development using various laboratory techniques such as UPLC, LC-MC, Nano drop, Osmometer, Karl Fisher etc.
• Routine UPLC analysis of RNA oligonucleotides (crude sample, fractions, pool, pre & post-TFF samples) for multiple guide RNA.
• Maintain a log sheet for all in-process sample analysis
• Maintain the lab instruments such as UPLC, Nano drop, LC-MS etc. in good operational condition after use
• Documents data in the Prime’s project specific folder, write a project summary report in brief and share results at scientific team meetings.

Qualifications:

• Must be enrolled in the undergraduate/advanced degree program at the time of Co-op program
• Excellent written and oral communication skills, good organization skills, the ability to multi-tasks, and work as a team player and independently.
• A passion for learning and contributing to multiple facets of a program
• Have completed General Chemistry, Analytical Chemistry lecture/lab course

Preferred Qualifications: 

• Prior relevant internship/Co-op experience.
• Familiarity working in chemistry laboratory, and experience with instrumentation such as UPLC, LC-MS, Nano drop is a plus.
• Familiarity about drug substance characterization is a plus

What We Offer:

• A cutting-edge scientific team open to mentorship and networking
• Full reimbursement for monthly commuting costs including subway, commuter rail, parking, Bluebikes, etc.
• Participation in regular scientific seminars with industry experts
• Full participation in employee activities including learning and development offerings, social activities, etc.