Who We Are

23andMe, the leading consumer genetics and research company, has accumulated a wealth of genotypic and phenotypic information from participants committed to improving human health through advances in genomics. Our Therapeutics team in South San Francisco leverages this data to discover and develop new treatments that can offer significant benefits for patients with serious, unmet medical needs.

This dedicated research and drug development group identifies novel targets using 23andMe’s genetic database and performs preclinical research to advance programs towards clinical development. We currently have programs across several therapeutic areas, including but not limited to oncology, respiratory, and cardiovascular diseases. More information about our Therapeutics team is available at https://therapeutics.23andme.com/.

The VP, Clinical Development will be responsible for advancing 23andMe’s therapeutics programs from pre-IND stage through all phases of clinical development for 23andMe owned and led programs, and will provide clinical development input for earlier stage programs and partnered programs. This person will be expected to exert broad influence across the organization, both scientifically and strategically, including contributing to the advancement of future clinical development strategy at 23andMe across all clinical indications. This individual will possess outstanding leadership skills, including the ability to hire and develop talent, to develop high functioning teams, and will have demonstrated a track record for successful delivery of small and/or large molecule therapies into clinical trials leading to regulatory approvals and demonstrated collaborativeness with academic, industry, advocacy and regulatory thought leaders.. The successful individual will join a dynamic, enthusiastic, innovative and collaborative team who are discovering new opportunities for therapeutic intervention and advancing impactful medicines toward regulatory approval. The successful individual will be passionate about his or her focus on patients and will inspire others.

What You’ll Do

• Provide guidance and strategic input to project and development team leaders in areas such as developing target candidate and product profiles; selecting, validating and developing clinical biomarkers; understanding PK/PD relationships
• Chair appropriate internal governance committees and make key decisions regarding clinical development strategy and prioritization
• Provide clinical perspectives to preclinical sciences and strategically guide IND-enabling studies that will support clinical plans
• Relate science/mechanisms of action to expected clinical profile in diverse therapeutic areas
• Contribute to the utilization of human genetic information in clinical drug development
• Define criteria for medical needs and selection of novel targets
• Provide leadership to and support the success of new and existing collaborations/alliances with academic institutions and pharma/biotech companies
• Work with senior leadership to help represent the company as a senior translational/medical spokesperson at appropriate scientific, medical, regulatory, business and other professional meetings
• Direct a fit-for-purpose organization to inform and execute clinical development plans from clinical trial initiation through global regulatory approvals with concurrent predictive biomarkers as appropriate
• Coach, mentor and manage employees, with varying levels of experience, for performance and scientific growth
• Maintain compliance with all company policies and procedures
• Perform other related duties as assigned

What You’ll Bring

• MD degree or equivalent with postgraduate clinical training and prior clinical investigator experience; PhD or equivalent in a basic science field preferred
• Substantial drug development industry experience including leading IND filings, pivotal phase 3 clinical trials, and NDA/BLA filings
• Clinical research experience in oncology or immune-mediated disease with a proven track record of quality publications
• Knowledge of applied research sufficient to understand how translational science enables the evolution into Clinical Development
• Experience with large molecule candidate selection
• Understanding of clinical evidence base guiding the use of molecular markers in patient selection
• Working knowledge of genetic/genomic and bioinformatics technologies and their application to translational approaches
• Ability to collaborate with internal and external multi-disciplinary research and development teams
• Experience providing input into therapeutic target selection and validation
• Outstanding organizational leader and mentor, with a track record of organization/team-building, talent attraction, and retention
• Exceptional written and verbal communication capabilities

About Us

23andMe, headquartered in Sunnyvale, CA, is a leading consumer genetics and research company. Founded in 2006, the company’s mission is to help people access, understand, and benefit from the human genome. 23andMe has pioneered direct access to genetic information as the only company with multiple FDA authorizations for genetic health risk reports. The company has created the world’s largest crowdsourced platform for genetic research, with 80 percent of its customers electing to participate. The platform also powers the 23andMe Therapeutics group, currently pursuing drug discovery programs rooted in human genetics across a spectrum of disease areas, including oncology, respiratory, and cardiovascular diseases, in addition to other therapeutic areas. More information is available at www.23andMe.com.

At 23andMe, we value a diverse, inclusive workforce and we provide equal employment opportunity for all applicants and employees. All qualified applicants for employment will be considered without regard to an individual’s race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws.  If you are unable to submit your application because of incompatible assistive technology or a disability, please contact us at [email protected]. 23andMe will reasonably accommodate qualified individuals with disabilities to the extent required by applicable law.

Please note: 23andMe does not accept agency resumes and we are not responsible for any fees related to unsolicited resumes. Thank you.

Pay Transparency
23andMe takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area.  The successful candidate’s starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future.