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Full-Time

Scientist II or Senior Scientist

Immunology

Posted on 6/27/2024

Kymera Therapeutics

Kymera Therapeutics

201-500 employees

Develops targeted protein degradation therapies

Hardware
Biotechnology

Mid, Senior

Belmont, MA, USA

Category
Biology Lab & Research
Biology & Biotech
Requirements
  • Extensive hands-on experience with isolation and culture of primary immune cells
  • Experience with developing flow multi-plex panels to identify immune subsets
  • Familiarity with immune cellular assays such as M1 macrophage polarization, B cell differentiation, and Ig class switching assays
  • Ability to summarize literature findings to support scientific and technical strategies
  • Experience with software such as FlowJo and GraphPad Prism
  • Attention to detail and proven track record in handling, analyzing, and recording experimental data
Responsibilities
  • Independently design and execute on cellular assay strategy to support indication selection and expansion of lead optimization program
  • Develop cytokine release, proliferation, and differentiation immune cell assays using healthy and diseased samples, with a focus on B cells and monocytes
  • Profile innate and adaptive immune cells by flow cytometry multi-plex assays
  • Independently analyze and present findings at group and project team meetings

Kymera Therapeutics develops treatments by targeting and breaking down specific proteins that contribute to diseases, particularly cancer and immune disorders. Their main technology, the Pegasus Platform, enables them to identify these harmful proteins and create drug candidates aimed at effectively treating various conditions. Unlike many competitors, Kymera focuses on targeted protein degradation, which can lead to more precise therapies. The company's goal is to create next-generation medicines that meet unmet medical needs, supported by partnerships with organizations like Sanofi to enhance their research and development efforts.

Company Stage

IPO

Total Funding

$879M

Headquarters

Cambridge, Massachusetts

Founded

2016

Growth & Insights
Headcount

6 month growth

0%

1 year growth

5%

2 year growth

29%
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Simplify's Take

What believers are saying

  • Kymera's recent $275 million public offering provides substantial capital to advance their clinical programs and expand their pipeline.
  • The FDA Fast Track designation for KT-333 could accelerate its development and bring it to market faster, benefiting patients with relapsed/refractory lymphomas.
  • Positive data from ongoing cancer drug trials and the unveiling of KT-294 highlight Kymera's potential for significant breakthroughs in oncology and immunology.

What critics are saying

  • The high costs and long timelines associated with biopharmaceutical R&D could strain Kymera's financial resources despite recent funding.
  • Dependence on partnerships, such as with Sanofi, introduces risks related to collaboration dynamics and milestone achievements.

What makes Kymera Therapeutics unique

  • Kymera Therapeutics leverages its proprietary Pegasus Platform for targeted protein degradation, setting it apart from traditional drug development approaches.
  • Their strategic partnership with Sanofi underscores their credibility and enhances their research capabilities, unlike smaller biotech firms with limited collaborations.
  • Kymera's focus on developing first-in-class therapies for cancer and immune disorders positions them uniquely in the biopharmaceutical market.
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