Principal/Senior Scientist
Cheminformatics
Posted on 1/17/2023
INACTIVE
Develops small molecule therapeutics to degrade disease-causing proteins
Company Overview
Kymera Therapeutics stands out as a pioneering biopharmaceutical company, utilizing its proprietary Pegasus platform to design small molecule protein degraders that target disease-causing proteins, a method that holds significant advantages over existing therapies. The company's focus on previously inadequately drugged biological pathways, particularly in immunology-inflammation and oncology, demonstrates its commitment to addressing unmet medical needs. With a culture driven by the invention of transformative medicines, Kymera is reshaping the approach to treating diseases where traditional modalities have fallen short.
Biotechnology
Company Stage
N/A
Total Funding
$879M
Founded
2016
Headquarters
Watertown, Massachusetts
Growth & Insights
Headcount
6 month growth
↑ 2%1 year growth
↑ 14%2 year growth
↑ 41%Locations
Belmont, MA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
Desired Skills
Python
Data Analysis
CategoriesNew
Biology & Biotech
Requirements
- PhD, or equivalent, in the field of computational chemistry, cheminformatics, or computer science with 5+ years of experience working in small-molecule drug discovery teams in a pharma or biotech setting
- Strong track record of applying Cheminformatics techniques for hit finding, hit expansion, data analytics, datamining and visualization
- Strong programming skills in Python required
- Experience with automation and informatics platforms KNIME or Pipeline Pilot
- Ability to independently solve problems, to think critically and creatively as part of a fast-paced and multidisciplinary team
- Ability to communicate clearly and concisely with all stakeholders
Responsibilities
- Working closely with project teams, apply cheminformatics tools to help the team make data-driven decisions
- In collaboration with Lead Discovery, develop and deploy HTS triage workflows, including screening library analysis/design, hit deconvolution, SAR analysis, datamining, and hit selection
- Develop and deploy predictive models and tools in project teams to help optimize potency or ADMET properties
- Interface with IT and external partners/CROs to develop and optimize the computational discovery infrastructure including cloud resources, collaborative discovery interface, KNIME, Pipeline Pilot, and other automation interfaces