Manager/Sr Manager
Clinical Drug Supply
Posted on 1/12/2023
INACTIVE
Develops targeted cancer therapies using synthetic lethality
Company Overview
Tango Therapeutics, a biotechnology firm, stands out due to its unique approach to cancer treatment, utilizing advances in DNA sequencing and CRISPR-based target discovery to develop novel medicines targeting cancer vulnerabilities. The company's focus on synthetic lethality, a method that targets specific genes in cancer cells leaving normal cells largely unaffected, offers a potential for enhanced anti-tumor efficacy and reduced toxicity. Furthermore, Tango's patient-centric approach and deep understanding of genetic subtypes of cancer enable it to identify novel drug targets and combinations, accelerating the development of transformational new therapies for patients with well-defined populations currently lacking effective treatment options.
Data & Analytics
Biotechnology
Company Stage
N/A
Total Funding
$537M
Founded
2017
Headquarters
Boston, Massachusetts
Growth & Insights
Headcount
6 month growth
↑ 12%1 year growth
↑ 26%2 year growth
↑ 51%Locations
Dorchester, Boston, MA, USA
Experience Level
Entry
Junior
Mid
Senior
Expert
Requirements
- At least five years of clinical drug supply experience in a clinical research environment, most of which should be in industry; global clinical trial experience is strongly preferred
- Bachelor's Degree in a life-science-based subject, advanced degree preferred
- Experience in early phase drug development including manual drug supply planning and tracking
- Cross-collaboration proficiency with clinical, GMP, CMC and Quality
- Solid understanding of FDA and ICH GCP guidelines to ensure the appropriate conduct of clinical studies in the United States related to clinical drug supply
- Good verbal and written communication skills including review of clinical documents
- Good organizational skills and ability to work independently
- Proven track record working within multi-disciplinary teams in the biotech or pharmaceutical industry
- Attentive to detail and capable problem-solver
Responsibilities
- Drug Supply Management of first-in-human and early phase clinical trials of development candidates
- Support cross functional teams and CRO/vendor management related to clinical supply aspects
- Participate in the review of outsourcing strategies and proactively plans for clinical supply including packaging and labeling, storage, and distribution
- Manage clinical labeling requirements
- Manage inventory at depots and clinical sites
- Responsible for representing drug supply management on cross-functional project teams and Vendor/CRO operational meetings and ensuring compliance with operational standards and procedures
- Participate in the review of departmental SOPs and controlled documents to ensure compliance
- Develop and maintain strong, collaborative relationships with key stakeholders within cross functional teams including GMP and CMC
- Manage the pharmacy manual creation and management as applicable
- Support the set up, user requirements and oversight of IWRS for later phase trials
- Additional duties and responsibilities as required