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Vice President
Drug Metabolism and Pharmacokinetics, Dmpk
Confirmed live in the last 24 hours
Belmont, MA, USA
Experience Level
  • 10+ years prior Biotech/Pharmaceutical experience preferred with a track record of successfully leading DMPK efforts for small molecule drug discovery programs through to IND
  • Highly analytical, decisive, goal-oriented, and timeline sensitive while maintaining the highest of scientific and ethical standards
  • Strong understanding of guidance from regulatory agencies on DMPK assays and qualification
  • Excellent interpersonal, organization, verbal and written communication skills
  • Problem-solving skills and attention to detail
  • Ability to organize and prioritize tasks in a timely and accurate manner
  • Ability to meet tight deadlines and to work collaboratively in a dynamic environment
  • PhD within the DMPK discipline complemented by extensive experience within a small molecule drug discovery setting
  • Function as a key member of Remix's scientific leadership team, providing scientific expertise, strategic planning and goal-oriented execution
  • Lead DMPK function in support of drug discovery and development projects
  • Prioritize DMPK activities, identify and manage external CRO and consulting resources, balancing multiple priorities under time and resource constraints
  • Work closely with medicinal chemistry and biology groups to generate, analyze and integrate PK and ADME data into lead optimization efforts
  • Define appropriate DMPK parameters for lead optimization and candidate selection leading to the estimation of safe and efficacious first in human clinical dose and regimen for novel therapeutics, as well as predicted clinical PK and PK/PD profiles
  • Deliver non-clinical DMPK packages and study reports within regulatory guidelines and author IND sections of regulatory filings
  • Provide bioanalytical and assay expertise to enable pre-clinical pharmacologic assessments of novel small molecules
  • Participate in budgeting and due diligence activities
Remix Therapeutics
RNA processing & therapeutic solutions company