Full-Time

Clinical Laboratory Scientist

Prenatal

Posted on 8/12/2026

BillionToOne

BillionToOne

501-1,000 employees

QCT-based molecular diagnostics for prenatal, oncology

Compensation Overview

$59.14 - $86.97/hr

+ Shift differential + Equity options + Corporate bonus + 4% company retirement match

Union City, CA, USA

In Person

On-site position.

Bachelor's

Category
Medical, Clinical & Veterinary (1)
Required Skills
Word/Pages/Docs
Excel/Numbers/Sheets

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Requirements
  • A Bachelor's degree in the chemical, physical, or biological sciences is required.
  • At least 1-2 years of Clinical Laboratory Scientist experience in a clinical setting is required.
  • A current California Clinical Laboratory Scientist License meeting Testing Personnel requirements under CLIA regulations, 42 CFR Part 493, is required; an ASCP, CGMBS, or generalist license is required.
  • Hands-on training and experience with manual molecular biology protocols, including DNA extraction and polymerase chain reaction, are required.
  • Advanced knowledge of Google Docs, Microsoft Word, Microsoft Excel, basic statistics, and LIMS systems is required.
  • The ability to work flexibly and meet specified timeframes is required.
  • Strong verbal and written communication skills are required.
Responsibilities
  • Perform clinical laboratory assays to provide data for the diagnosis, treatment, and prevention of disease.
  • Perform quality control studies to ensure the accuracy of clinical data.
  • Verify instrument performance by checking and calibrating specific laboratory instruments and documenting data.
  • Organize and contribute to research and development, CLIA technology transfer, troubleshooting, training, and validations.
Desired Qualifications
  • Start-up experience is preferred.
  • Knowledge of medical genetics is preferred.
  • Experience in a cell-free DNA setting is preferred.

BillionToOne provides molecular diagnostic testing for prenatal screening and cancer monitoring. Its QCT technology detects and measures DNA variations at a single base-pair level, enabling precise analysis across the three billion DNA letters. The main products, Northstar Select and Northstar Response, are tests that help doctors choose the best first-line therapy and track how well treatment is working, respectively. The company markets these services to healthcare providers who perform the tests and use the results to guide patient care. Unlike some rivals, BillionToOne emphasizes high-resolution DNA assessment and scalable diagnostic services through provider partnerships, aiming to improve accuracy, speed, and access. Its mission is to make molecular testing more accurate, efficient, and accessible to all, driven by growth, equality, and teamwork.

Company Size

501-1,000

Company Stage

IPO

Headquarters

Menlo Park, California

Founded

2016

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Simplify Jobs

Simplify's Take

What believers are saying

  • Q2 2026 revenue hit $109.4 million, up 64%, with positive operating income.
  • Oncology revenue jumped 176% in Q2 2026 after Northstar Select and Response expansion.
  • Management reaffirmed 2026 revenue guidance of $450 million to $465 million, signaling execution confidence.

What critics are saying

  • Illumina sued BillionToOne on May 7, 2026 over prenatal-test patent infringement.
  • Prenatal pricing depends on reimbursement; any payer pushback hits the $94.2 million franchise.
  • Competitors like Natera and Guardant can outspend BillionToOne on sales and evidence.

What makes BillionToOne unique

  • Unity Complete and Northstar use single-molecule cfDNA counting for rare-variant detection.
  • August 17, 2026 launched 130-gene fetal panel, the largest single-gene NIPT panel.
  • September 1, 2026 Northstar Origin added tissue-of-origin prediction without extra blood draws.

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Benefits

Competitive pay

Retirement savings package

Parental leave

Free snacks & lunches

Medical, dental, & vision premiums

On campus perks

Free-on-site EV charging

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

0%

2 year growth

0%
PR Newswire
Sep 1st, 2026
BillionToOne launches Northstar Origin liquid biopsy test to identify cancer tissue of origin

BillionToOne has launched Northstar Origin, a liquid biopsy add-on test that predicts tissue of origin from circulating cell-free DNA for patients with cancer of unknown primary or uncertain cancer diagnosis. The test requires no additional tissue or separate blood draws beyond what's already collected for therapy selection. In a validation study of 1,578 patients, Northstar Origin identified the correct tissue of origin as its top prediction in 87% of cases and within its top three predictions in 91% of cases. The classifier was developed using 6,025 blood samples from advanced cancer patients. The company also expanded its Northstar Select panel from 84 to 102 genes, adding 18 new genes including MTAP deletion. The test is designed to help community oncologists make diagnostic decisions, as roughly 3-5% of new cancer diagnoses present as cancer of unknown primary.

Yahoo Finance
Aug 28th, 2026
BillionToOne CTO sells $1M in shares under pre-planned trading arrangement

David Tsao, co-founder and chief technology officer of BillionToOne, sold 10,000 shares of Class A Common Stock for $1 million on 25 August 2026. The transaction involved a cashless exercise of fully vested stock options at $2.80 per share, with the resulting shares sold at a weighted average price of $100. The sale was executed under a Rule 10b5-1 trading plan adopted in March 2026, indicating it was pre-scheduled rather than discretionary. Tsao retains 1,000 direct shares and 580,000 stock options. BillionToOne, a Menlo Park-based molecular diagnostics company, reported second-quarter revenue of $109.4 million, representing 64% year-over-year growth. The company has a market capitalisation of $4.4 billion and generated $397.4 million in trailing 12-month revenue with $33.5 million in net income.

Yahoo Finance
Aug 6th, 2026
BillionToOne reports $109.4M Q2 revenue, up 64% year-over-year, reiterates 2026 guidance

BillionToOne, a molecular diagnostics company, reported second-quarter 2026 revenue of $109.4 million, up 64% from $66.6 million in the same period last year. Prenatal clinical testing revenue reached $94.2 million, whilst oncology testing revenue surged 176% to $13.7 million. The company delivered 196,000 tests during the quarter, a 35% increase year-over-year. Gross profit margin improved to 70% from 65%. BillionToOne posted operating income of $5.5 million, compared to a $1.6 million loss in Q2 2025. The firm reiterated its full-year 2026 revenue guidance of $450 million to $465 million, representing 48% to 52% growth over 2025. BillionToOne announced plans to expand its Unity Fetal Risk Screen with a 130-gene panel launching 17 August 2026.

Yahoo Finance
Aug 6th, 2026
BillionToOne revenue surges 64% to $109M as oncology jumps 176% and prenatal grows 56%

BillionToOne reported strong second-quarter results for 2026, with total revenue reaching $109.4 million, up 64% year-over-year. Prenatal revenue rose 56% to $95.8 million, while oncology revenue surged 176% to $13.7 million. The company achieved gross margins of 70.5%, up 5 percentage points from the previous year. BillionToOne posted operating income of $5.5 million and net income of $8.1 million, or $0.15 per diluted share. Test volumes increased 35% year-over-year to approximately 196,000 tests, with average selling prices rising 21% to $551 per test. The company generated $9.1 million in cash from operations and $5.1 million in free cash flow. BillionToOne maintained its full-year 2026 revenue guidance of $450 million to $465 million.

GenomeWeb
Aug 5th, 2026
BillionToOne to launch NIPT, liquid biopsy add-ons as Q2 revenue rises 64 percent.

BillionToOne to launch NIPT, liquid biopsy add-ons as Q2 revenue rises 64 percent. NEW YORK - BillionToOne said on Wednesday that its second-quarter revenue grew 64 percent year over year on the back of strong prenatal and oncology clinical testing sales. Get the full story with GenomeWeb Premium. Only $95 for the first 90 days. Full site access Interest-based email alerts Premium Access - Trial Offer $95.00 for 3 month Already a GenomeWeb member? LoginLogin

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