Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity.
The Importance of the Role
The summer internship in downstream process development will give insight into the manufacturing process for complex biomolecules along with hands-on production experience using bioprocessing techniques – including bioreactors, depth filtration, tangential flow filtration, and fast protein liquid chromatography. Interns will not only have the opportunity to interact with the downstream team, but also the upstream, analytical development, and formulation teams to learn how drug products are developed safely, cost-effectively, and efficiently from lab scale (≤10L) to commercial scale (>1000L).
In addition, interns will be exposed to leading-edge development approaches and technologies used to overcome major challenges in the bioprocessing sector, such as design of experiments, process intensification, and high-throughput automation. Timing permitting, the intern will also experience what goes into tech transfer at the early-stage development site. The highly collaborative environment of Sarepta Therapeutics will expose the intern to the nature of the job of multiple teams, departments, and leadership in getting therapeutic molecules from research to the clinic.
The Opportunity to Make a Difference
Assist downstream scientists in the design, preparation, and execution of process development experiments
Work independently on a research project (selected by the mentor) aimed at optimizing a select unit operation within the downstream process for AAV manufacturing
Participate in weekly process development meetings
Refinement of laboratory skills via introduction to new experimental techniques, exposure to current challenges in bioprocess research, and perspectives on the practical aspects of drug development
More about You
Undergraduate (junior or senior) or graduate student majoring in a science-oriented field, preferably (but not limited to) chemistry, biochemistry, or bioengineering
One year of laboratory research experience or equivalent required (two or more preferred)
Experience with protein purification is desired
Experience with statistical software such as JMP or Prism is a plus
Proficiency in Microsoft Office (Word, Excel, PowerPoint) is required
This role is on-site and will require regular work in a laboratory setting
Program Timeline:
This application is for a 12-week summer internship program that will start on May 19th and conclude on August 8th, 2025.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
#LI-Onsite#LI-MC1This position requires work on site at one of Sarepta’s facilities in the United States.The targeted salary range for this position is $21 - $25 per hour depending upon years of education completed and nature of role.Candidates must be authorized to work in the U.S.Sarepta Therapeutics offers a competitive compensation and benefit package.Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
