Co-Op Assignment Overview

Prime Medicine is seeking a co-op for the Fall 2023 cycle with experience in Biology to join the Hematology/Immunology team. The qualified candidate will work with a highly collaborative fast paced project team to build assays, test delivery methods, and validate promising Prime Editors for hematological, immunological and cell therapy indications. In this position, you will learn and perfect cell and molecular biology skills and develop a deep understanding of gene editing and hematopoietic stem cell and immune cell biology. 

Primary Responsibilities:

• Grow and maintain primary human cells and cell lines using aseptic techniques
• Set up assays to evaluate different methods of delivery of prime editing reagents
• Assist with clonal analysis of prime edited cells 
• Process gDNA for sequencing analysis (extraction, PCR, MiSeq preprocessing)
• Prepare samples and running flow cytometry assays
• In vivo sample harvesting and processing for downstream analysis
• Data analysis, interpretation, and presentations within the team

Qualifications:

• B.S. candidate in Cell & Molecular Biology or related major
• Basic knowledge of molecular biology, cell biology and biochemistry.  
• Excellent troubleshooting and communication skills 
• Ability to work independently and within a team

Preferred Qualifications:

• Hands-on experience with cell culture is preferred
• Experience with basic molecular biology assays (DNA extraction, PCR etc)
• Familiarity with excel and PowerPoint for data analysis
• Independently motivated, detail-oriented, and excellent problem-solving abilities

What We Offer:

• A cutting-edge scientific team open to mentorship and networking
• Full reimbursement for monthly commuting costs including subway, commuter rail, parking, Bluebikes, etc.
• Participation in regular scientific seminars with industry experts
• Full participation in employee activities including learning and development offerings, social activities, etc.