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Director – Toxicology
Confirmed live in the last 24 hours
Alameda, CA, USA
Experience Level
  • PhD degree in toxicology, pharmacology, or related discipline and 3+years of industry-related experience; or MS degree in a related discipline and 5+ years of experience
  • Minimum of 3 years of industry experience in all aspects of preclinical safety assessment including genotoxicity, general toxicology, developmental and reproductive toxicology, and safety pharmacology
  • Knowledge of regulatory requirements and expectations for nonclinical packages to support first in human clinical study
  • Enthusiasm for working with novel therapeutic modalities and lead teams to address safety issues
  • Experience in gene therapy and/or cardiovascular/liver disease field is desirable but not necessary
  • Demonstrated knowledge of general regulatory requirements and expectations for nonclinical safety assessment packages to support first in human study
  • Excellent communication skills with an ability to communicate across a variety of high-level stake holders
  • Strong attention to detail, experience in monitoring work to assure quality, accuracy, and thoroughness
  • Lead the effort and manage nonclinical safety pharmacology and toxicology studies across all Scribe development programs
  • Serve as a core project team member representing toxicology/safety on multi-disciplinary project teams facilitating development of gene editing therapies
  • Define and mitigate nonclinical safety findings, and assess the relevance of toxicological findings to safety in human
  • Identify and leverage external experts in potential findings related to nonclinical safety assessment
  • Author toxicology summaries for regulatory submissions
  • Assist in building of high performing team by instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of accountability
Scribe Therapeutics

11-50 employees