Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:

Seeking a highly motivated and talented peptide chemist to join our discovery Peptide and Bioconjugation research group. The successful candidate will work on the design, synthesis and characterization of novel peptides to discover next-generation peptide-based therapeutics. Your expert synthetic knowledge and proven design and synthetic accomplishments will enable you to have significant impact on Neurocrine’s projects. This is an exciting position to help discover peptide therapeutics of the future.

Your Contributions (include, but are not limited to):

Lead projects and teams towards agreed upon goals, ultimately working towards clinical candidate peptide nomination
Synthesis, purification and characterization of peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, purification, analytical and biophysical techniques
Contributes to project teams towards agreed upon goals, ultimately working towards candidate peptide nomination
Independent data-driven optimization of peptide SAR
Effective communication of scientific rationale, results and interpretation at project, team and departmental meetings
Active collaboration and sharing of expertise with colleagues

Requirements:

BS/BA degree in chemistry or closely related field and 5+ years of experience OR
MS/MA degree in chemistry or closely related field and 3+ years of similar experience OR
PhD in chemistry or related field and 2+ years of similar experience
Proficient in all aspects of modern peptide synthesis, purification and analysis; capable of immediate independent laboratory work on solid- and solution-phase chemistry
Strong publication record of accomplishment
Strong understanding of peptide structure and associated biophysical techniques to assess peptide structure, stability and behavior in solution
Experience in protein-peptide bioconjugation and purification a plus
Excellent interpersonal skills with strong oral and written communication abilities
Assimilates data and research findings outside of Neurocrine for application to new scientific projects
Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools
Excellent computer, communications, problem-solving, and analytical thinking skills
Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency

#LI-DM1

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.

The annual base salary we reasonably expect to pay is $108,600.00-$157,350.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

Sr. Scientist

Peptide / Bio-organic Chemistry

Neurocrine Biosciences

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