Senior Research Scientist
Biotherapeutic Purification/Downstream Processing
Posted on 7/19/2023
INACTIVE
AbCellera Biologics

501-1,000 employees

Accelerates antibody drug discovery with data science
Company Overview
AbCellera stands out as a leader in the biotech industry due to its unique approach to antibody drug discovery, combining expert teams, advanced technology, and data science to expedite the process from target to clinic across various therapeutic areas. The company's competitive edge lies in its ability to enable swift progress, cost reduction, and problem-solving in drug development for both innovative biotechs and leading pharmaceutical companies. Furthermore, AbCellera's commitment to technical innovation is evident in its recent presentation of new data on two T-Cell Engager Programs at SITC 2023, demonstrating its active role in advancing the field.
AI & Machine Learning
Data & Analytics
Biotechnology

Company Stage

Series A

Total Funding

$393.7M

Founded

2012

Headquarters

Vancouver, Canada

Growth & Insights
Headcount

6 month growth

-2%

1 year growth

17%

2 year growth

79%
Locations
Vancouver, BC, Canada
Experience Level
Entry
Junior
Mid
Senior
Expert
Desired Skills
Data Analysis
CategoriesNew
AI & Machine Learning
Lab & Research
Requirements
  • Providing leadership in antibody purification, including designing, planning and executing experiments, either independently or in collaboration with teammates
  • Establishing and optimizing protocols for antibody purification/downstream processing operations, including high throughput and bench-scale production
  • Engaging with multiple teams to build optimal solutions for challenges in antibody purification and production, including developing process steps to clear impurities and maximize product yield
  • Solving problems at a high level
  • Training, mentoring, and supervising members of a dynamic team
  • Liaising with CMC teams and other partners, communicating project updates and deliverables
  • Developing and implementing standard operating procedures
  • Organizing, supporting, and collaborating with team members to meet project deliverables and timelines
  • You are a creative problem solver and fast learner who believes in team work to tackle the most challenging scientific problems
  • You are self-motivated and have the initiative and drive to meet goals under tight project timelines
  • You think critically, are curious and want to explore new technologies, opportunities and integrate automation to improve the antibody production workflow and process
  • A PhD in Biological and/or Chemical Sciences (Biochemistry, or other relevant fields) and 8+ years of experience, including 5+ years of experience in industry
  • Extensive experience in protein purification and downstream processing technologies, including IMAC/HIC/IEX Chromatography and Tangential Flow Filtration
  • Great interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
  • Strong knowledge of protein expression/upstream processes using transient and/or stable mammalian cell culture systems (HEK, CHO)
  • Experience developing processes for robustness, scale-up and CMC progression is desired
  • Knowledge of analytical technology like SEC, light scattering and thermal denaturation is an asset
  • Experience with high-throughput protein expression and purification or automation is an asset
  • A strong data analysis skill set and the ability to interpret, communicate, and document large data sets
  • Excellent documentation and organizational skills
  • Impeccable attention to detail