Scientist – Biologics Analytical Development and Attribute Sciences

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Business Unit Summary

Our Biologics Development team is responsible for development and transfer of safe, efficient, and approvable biologics drug substance manufacturing processes and analytical methods for all of BMS’ biologics portfolio. We work closely with other BMS units to support our clinical pipeline through to late stages of clinical development. Innovation is at the core of what we do, with an intense focus on efficiency, speed, robustness, and approvability of our processes and methods. Here, you’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, pursue innovative ideas, and advance professionally alongside some of the brightest minds in Biopharma.

The Biologics Analytical Development and Attribute Sciences team seeks to leverage the best in analytical chemistry, state-of-the-art instrumentation, and automation to enable production of high quality biotherapeutics for clinical trials and commercial manufacturing. The biotherapeutic modalities we support include monoclonal antibodies, bispecific and trispecific antibodies, fusion proteins, antibody-drug conjugates, viral vectors, and more.

Position Summary

This position will leverage analytical chemistry and lab automation to develop and apply state-of-the-art analytical methods for quality testing of protein therapeutics.

Key Responsibilities

• Support analytical testing for monoclonal antibodies and fusion proteins, including HPLC/UPLC, isoelectric focusing, capillary electrophoresis, ELISA, qPCR, etc. Mass Spectrometry experience is beneficial.
• Implement state-of-the-art lab automation to simplify and streamline lab work (Tecan, Andrew+, others)
• Evaluate new analytical methods for improving analytical capability and assay performance.
• Support method standardization activities in collaboration with partner groups at New Brunswick NJ, Devens MA, and other BMS sites.
• Authoring technical reports, methods, and/or regulatory submissions to support our pipeline.
• Collaborate closely with Research and Development, Characterization, Manufacturing Process Development, and Clinical Manufacturing teams. 
• Maintain accurate and up to date laboratory e-notebook documentation.
• Learn analytical skills needed to support future assays for the next generation of biologics programs.
• On-site presence is required to complete the primary responsibilities of this position.  Occasional travel to the BMS New Brunswick, New Jersey site is expected.
• This role requires office work, chemical laboratory work, computer work, group meetings, and thus involves the ability to work at a laboratory bench and in fume hoods, working with analytical instruments, repetitive motion including bending and lifting small containers/equipment.
• Sustain a safe and high-performance laboratory environment. This is essential as the candidate will be working with potentially hazardous materials (corrosives, flammable solvents, toxic or potent compounds).

Qualifications & Experience

• A PhD/Doctorate degree in Analytical Biochemistry, Analytical Chemistry, Biotechnology, or related field with 0 to 2 years of relevant industry and/or academic experience, or a Masters degree and 2 to 4 years of relevant experience, or Bachelors degree and 5 to 7 years of relevant experience.
• Excellent communication and organizational skills, supported by a strong record of publications and presentations.
• The ability to work collaboratively in a team environment is essential.
• Experience in a variety of protein analytical techniques, which may include affinity LC, N-glycan characterization, iCIEF, size exclusion HPLC and UPLC, capillary electrophoresis, ELISA, and mass spectrometry.
• Experience with sample preparation techniques a plus including affinity purification and other SPE approaches. 
• Experience in programming and usage of robotic liquid handlers, such as Tecan, Hamilton or similar platforms, is beneficial.
• Knowledge and experience of nucleotide bioanalytical techniques is useful, including southern blot, northern blot, reverse transcription, and qPCR.
• Skill in utilizing scientific computer software is beneficial, including Empower, LIMS software, SYMYX ELN, JMP, Microsoft office applications.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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