Full-Time

Applied AI Workflow Clinical Scientist

Updated on 9/16/2026

Deadline 9/17/26
Pfizer

Pfizer

10,001+ employees

Biopharmaceutical company develops medicines and vaccines

Compensation Overview

$139.1k - $231.9k/yr

+ 17.5% bonus target + Share-based long-term incentive program

No H1B Sponsorship

Cambridge, MA, USA

Hybrid

Must live within commuting distance and work on-site an average of 2.5 days per week. Relocation assistance may be available.

Bachelor's, Master's, PhD

Category
Software Engineering (1)
Required Skills
LLM
Python
RAG
Biostatistics

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Requirements
  • PhD with at least 1 year of experience, or a Master's degree with at least 5 years of experience, or a Bachelor's degree with at least 6 years of experience.
  • Direct experience supporting clinical development, clinical science, clinical operations, clinical data review, or regulatory science, with a strong working understanding of Good Clinical Practice, clinical trial conduct, and the drug development process.
  • Experience with omics or other high-dimensional data from clinical or translational studies, including biomarker and endpoint work, patient stratification, or exploratory and mechanistic analysis, and translating results into development decisions.
  • Hands-on experience applying large language models, agentic artificial intelligence, or workflow automation in scientific work.
  • Ability to build practical, reusable workflows rather than one-off analyses.
  • Experience working directly with domain users to translate ambiguous needs into useful solutions.
  • Sound judgment regarding methodological rigor, model limitations, evaluation, and the appropriate role of human oversight in AI-enabled clinical and scientific workflows.
  • Permanent work authorization in the United States is required.
Responsibilities
  • Identify high-value, repeat use cases across inflammation and immunology clinical development and translational science where large language models, agentic artificial intelligence, and workflow automation can improve the speed, quality, and accessibility of the work, then design, build, and refine reusable AI tools.
  • Work directly with clinical scientists, clinical operations, biostatistics, translational teams, and computational biologists to understand workflow pain points, define fit-for-purpose solutions, and iterate toward scientifically useful and operationally adopted tools.
  • Work across the Digital ecosystem to prevent duplication and deploy existing platforms where appropriate, bringing scientific requirements and evaluation criteria to support build-or-buy decisions.
  • Apply fit-for-purpose evaluation, grounded outputs, documentation, guardrails, disclosure of model limitations, and human oversight to AI workflows, particularly when they involve Good Clinical Practice-governed or otherwise regulated data.
  • Concentrate on clinical execution, including study design, feasibility, data review, and submission readiness, and extend the approach over time to clinical omics and translational data.
  • Raise AI fluency among collaborators by demonstrating practical workflows, explaining trade-offs, and helping scientists build confidence in responsible use of large-language-model-enabled tools.
Desired Qualifications
  • Advanced degree in a clinical, life-science, computational-biology, or related quantitative field.
  • Coding experience in Python or a similar language sufficient to prototype, automate, and read engineering implementations.
  • Hands-on clinical scientist experience deploying artificial intelligence.
  • Experience in immunology and inflammation or an adjacent therapeutic area.
  • Experience with single-cell, spatial, proteomic, or other high-dimensional platforms applied to clinical samples.
  • Familiarity with scientific evidence synthesis, literature and document workflows, retrieval-augmented approaches, or multi-step workflows over structured and unstructured scientific information.
  • Experience with agentic orchestration, prompt and program design, workflow automation, or multimodal AI systems.
  • Familiarity with emerging regulatory expectations for AI in drug development, including interaction with the Food and Drug Administration or European Medicines Agency or contribution to submissions.
  • Experience deploying AI in regulated environments and working with external technology partners, vendors, or academic collaborators.
  • Strong publication or open-source record.

Pfizer is a global biopharmaceutical company that discovers, develops, manufactures, and sells medicines and vaccines for a range of health needs, including vaccines, oncology, and other specialized therapies. Its products work by using biological mechanisms to prevent or treat diseases—vaccines train the immune system to fight infections, while medicines target cancer and other conditions. Pfizer differentiates itself through its large worldwide footprint, broad portfolio across multiple therapeutic areas, and partnerships (notably with BioNTech) that expanded its reach in vaccines and cutting-edge therapies. The company also engages in public health initiatives, such as efforts to provide vaccines to underserved populations. Pfizer’s broad goal is to improve global health by delivering safe and effective medicines and vaccines through research, development, and wide international distribution.

Company Size

10,001+

Company Stage

IPO

Headquarters

New York City, New York

Founded

1849

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Simplify Jobs

Simplify's Take

What believers are saying

  • Q2 2026 revenue rose to $15 billion, and non-COVID products grew 5% operationally.
  • Pfizer raised 2026 guidance to $60.5 billion-$62.5 billion after Eliquis, Padcev, Vyndaqel strength.
  • Berobenatide entered Phase 3 planning, giving Pfizer a credible obesity franchise before 2028.

What critics are saying

  • Depo-Provera MDL exceeded 5,800 cases by July 2026, with late-2026 bellwethers looming.
  • Vyndamax still faces Apotex litigation in Delaware, preserving generic-entry uncertainty beyond 2031.
  • Ringaskiddy and Catania cuts show manufacturing contraction, signaling more restructuring through 2029.

What makes Pfizer unique

  • Seagen gives Pfizer leading ADCs: Padcev, Tivdak, Adcetris, Tucysa across oncology.
  • Pfizer still owns COMIRNATY distribution scale, with XFG vaccine approved August 27, 2026.
  • Vyndamax settlement extends U.S. exclusivity to June 1, 2031, stabilizing cardiomyopathy cash flows.

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Benefits

Health Insurance

Dental Insurance

Vision Insurance

401(k) Retirement Plan

401(k) Company Match

Paid Vacation

Paid Sick Leave

Paid Holidays

Hybrid Work Options

Relocation Assistance

Growth & Insights and Company News

Headcount

6 month growth

-5%

1 year growth

-5%

2 year growth

-5%
Yahoo Finance
Sep 10th, 2026
Medicus Pharma secures Pfizer ADC deal with $2M funding, advances SkinJect for rare cancer treatment

Medicus Pharma has secured a development and licensing agreement with Pfizer for a CD228-targeted antibody-drug conjugate programme focused on solid tumours, including refractory melanoma. Pfizer is providing approximately $2 million in development funding, plus inventory and infrastructure support. CEO Dr Raza Bokhari said the deal allows Medicus to continue from where Pfizer concluded its Phase 1 dose-escalation work, strengthening the company's position in precision oncology. Medicus is also advancing its SkinJect programme for basal cell carcinoma. Final clinical trial results identified the 200-microgram patch as the optimal dose for future studies. The company is preparing for the FDA-approved pivotal SkinJect 005 study whilst recruiting patients. An independent reimbursement analysis suggests SkinJect could achieve reimbursement levels of $25,000 or more per patient.

Yahoo Finance
Sep 8th, 2026
AbbVie beats Pfizer as top dividend stock with 53-year payout streak and 203% growth

AbbVie offers a smarter long-term dividend investment than Pfizer, despite Pfizer's higher 6.1% yield. AbbVie holds Dividend King status with 53 consecutive years of dividend increases and raised its payout by 5.5% this year to $1.73 per share. Over the past decade, AbbVie increased its dividend by more than 203% compared to Pfizer's 51%. AbbVie's revenue grew 138% during this period, whilst Pfizer's rose just 18%. AbbVie successfully navigated Humira's patent cliff through home-grown immunology drugs Skyrizi and Rinvoq. By 2025, these two drugs generated combined annual sales exceeding $25 billion, replacing Humira's peak revenue and pushing total company revenue to record highs. AbbVie's free-cash-flow dividend payout ratio stands at 65%, lower than Pfizer's 89%.

Yahoo Finance
Aug 28th, 2026
Pfizer's updated COVID vaccine ships as FDA approves narrower rollout for over-65s and high-risk groups

Pfizer received FDA approval for its updated Comirnaty COVID-19 vaccine on Thursday, with deliveries to pharmacies and clinics beginning immediately. The company's shares were trading at $27.9079 on 28 August. However, the market opportunity has significantly narrowed from pandemic levels. Eligibility is now limited to adults aged 65 and older, plus higher-risk patients aged 5 through 64. Despite Comirnaty having distributed over five billion doses worldwide historically, today's revenue potential is considerably more constrained. Pfizer faces competition from Moderna and the Novavax-Sanofi protein vaccine for this smaller patient pool. The company's current share price sits 5.27% above its estimated value of $26.51, suggesting investors are paying a premium before actual uptake and commercial results become clear.

Associated Press
Aug 27th, 2026
FDA approves Pfizer-BioNTech XFG-adapted COVID-19 vaccine for high-risk groups

Pfizer and BioNTech have received US Food and Drug Administration (FDA) approval for their 2026-2027 COVID-19 vaccine targeting the XFG variant. The vaccine is approved for adults aged 65 and older, and individuals aged 5 to 64 with underlying conditions that increase risk of severe COVID-19 outcomes. The FDA approval is based on clinical, non-clinical and real-world data demonstrating the vaccine generates strong immune responses against currently circulating SARS-CoV-2 variants, including XFG and other contemporary lineages. The XFG variant was selected following FDA guidance for fall 2026 vaccine composition. The vaccine will begin shipping immediately and will be available in US pharmacies, hospitals and clinics within days. To date, more than five billion doses of COMIRNATY have been distributed globally.

Yahoo Finance
Aug 24th, 2026
Pfizer and J&J navigate patent cliffs with newer drugs offsetting blockbuster losses

Pfizer and Johnson & Johnson are navigating patent cliffs as key drugs lose exclusivity, with their latest results showing differing stages of transition. Pfizer's revenue excluding COVID products grew 5% operationally in Q2 2026, with newer medicines like Padcev and Vyndaqel contributing. The company expects $9.7 billion in cost savings through 2029 to support margins during the transition. Johnson & Johnson's Innovative Medicine sales rose 7.8%, despite Stelara revenue declining 55%. Tremfya sales surged 72.5% to $2 billion, helping offset losses alongside growth from oncology and neuroscience products. Johnson & Johnson raised 2026 guidance, with reported sales expected to reach $101.1 billion and adjusted EPS of $11.68. Its MedTech division provides additional diversification that pure pharmaceutical company Pfizer lacks, suggesting Johnson & Johnson's transition is more advanced.