Company Overview
Cerevel Therapeutics is dedicated to unraveling the mysteries of the brain to treat neuroscience diseases. We are tackling neuroscience diseases with a differentiated approach that combines expertise in neurocircuitry with a focus on receptor selectivity. Our portfolio of pre-commercial neuroscience assets targets a broad range of central nervous system (CNS) disorders, including schizophrenia, epilepsy, Parkinson’s disease and substance use disorder.
Headquartered in the Greater Boston area, we are bold thinkers, deep experts, resilient pathfinders, and transparent partners who push the boundaries of scientific understanding to unlock breakthrough CNS therapies that have real impact on people’s lives.
Cerevel aspires to develop and nurture a culture characterized by trust, respect, courage, curiosity, and compassion, with a relentless focus on mission and results. Our patient-centricity guides our purpose, how we treat each other and what we work on every day. The successful candidate will bring their own unique thinking and approach to Cerevel while sharing our core values and convictions.
Role Summary:
This is an exciting role for a Senior Associate lab scientist to be part of the growing DMPK (Bioanalytical) group here at Cerevel. The ideal candidate will be contributing towards in vitro / in vivo BA and biomarker (BM) quantitation studies along the drug discovery path using cell-culture, quantitative bioanalysis and related lab skills, especially for early-stage programs in the company portfolio. This is a matrixed position that will involve frequent interactions with discovery research team members from cross-functional groups such as Chemistry, in vivo Biology, Translational Medicine and Toxicology. This role additionally offers a great learning/growth opportunity to improve the understanding of different aspects of the DMPK function in drug discovery and development.
Key Responsibilties
- Basic cell-culturing familiarity and good working experience to contribute with cell-line establishment and maintenance for ADME assays. In general, this Scientist will be expected to function in a professional, self-motivated way with moderate supervision and assistance from the supervisor/BA team
- Preparing and analyzing BA study samples and generating high quality bioanalytical/LC-MS data to support non-GLP studies, as part of a matrix environment. Also being involved in study design, in concert with all stakeholders
- Learn and perform new and existing quantitative biomarker assays – small molecule and/or proteins using LBA or LC/MS approaches
- Documenting the experimental design, results and conclusions in Electronic Lab Notebook (ELN) and uploading summary reports to Cerevel data repository including working via our new cloud-based LIMS platform
- Presenting scientific findings at internal and/or external scientific meetings
Required Qualifications
- BS (in Chemistry/Analytical Chemistry, Biochemistry, Biology or related discipline) with 2-5 years of work experience, preferably, in the industry will be required
- General lab skills including at least 1 year of cell culture work experience will be required
- Hands-on experience with LC-MS bioanalysis of small molecules will be required
- Strong learning capabilities, high scientific integrity, good interpersonal and communication skills will be required
- Ability to work in a fast-paced environment, as well as in a team setting in a self-motivated way will be required
Desired Qualifications
- Aspects of other modality experience (biologic, for example) will be an advantage. Exposure to LBA approach for quantitation will be preferred but not required
- Good understanding of BA and related processes used in the laboratory as well as a broader understanding of the drug discovery process and DMPK function will be preferred
Education
- BS (Cell/Molecular Biology, Biochemistry, Biology, Analytical Chemistry or related discipline)
Cerevel is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other characteristic protected by applicable law.
