POSITION SUMMARY
As the Manager of Variant Curation, you will help the Director/Sr. Director of Variant Curation oversee the operational responsibilities of the team to ensure curation tasks are performed efficiently and accurately, while also ensuring sufficient and well-trained staff are available to meet operational needs. 

PRIMARY RESPONSIBILITIES:

●    Alongside the Director/Sr. Director of Variant Curation, attend operational and cross-functional meetings with members of the wet-lab, Lab Directors, Quality Assurance, product managers, and Engineering teams, etc., and provide periodic updates to ensure alignment within the supervisors and production team.  
●    Monitor production metrics developed by the Director/Sr. Director of Variant Curation, and assign priorities to the production team to ensure turnaround times are met.
●    Initiate and manage compliance with QA, including NCRs, CAPAs, competencies, and documentation.

●    Improve the troubleshooting turnaround by delegating and managing resources based on business needs.
●    Review genetic variant data: interpret medical literature, online variant databases, and other references to classify variants according to the internal standard operating procedures (SOPs).
●    Provide operational support for the curation team and discuss clinical issues with Lab Directors as necessary.
Supervisory:
●    Establish goals, review and approve assigned work and provide mentorship to further develop  team members.
●    In conjunction with other supervisors, oversee individual productivity metrics and hold periodic check-ins to ensure team members meet expectations and deliverables.
●    Help onboard and guide junior supervisors and collaborate with other supervisors to prioritize work, validate new products, and improve workflows.
●    Perform various administrative tasks related to personnel management
●    Assist with corrective action plans and remedial training when necessary.
●    Maintain ongoing competency and support periodic updates to procedures and workflows.
●    Ensure timely completion of training requirements, including HIPAA and PHI security training

QUALIFICATIONS
●    Master’s degree required (PhD preferred) in genetics or related field.
●    5+ years of supervisory or team leadership experience in genetics/variant curation or related field (industry or clinical).
●    3+ years of experience in variant curation.
●    2+ Experience in a CLIA-certified laboratory setting analyzing and interpreting genetic/genomic data.

KNOWLEDGE, SKILLS, AND ABILITIES:
●    Expertise in the variant review and interpretation.
●    Excellent problem solving, conflict resolution, and decision-making skills.
●    Good written and oral communication skills.
●    Knowledge of CAP, CLIA, and state regulations (California and New York preferred).

PHYSICAL DEMANDS & WORK ENVIRONMENT:
●    Prolonged periods of working on a computer/laptop and occasional standing or sitting for extended periods.
●    Duties may occasionally require working shifts, weekends, or overtime.
Travel required for this position:
☒ Yes, up to 10%