Full-Time

Lead – Biomolecular Interactions

Posted on 1/30/2023

AbCellera Biologics

AbCellera Biologics

501-1,000 employees

Accelerates antibody drug discovery with data science

Data & Analytics
AI & Machine Learning
Biotechnology

Senior

Vancouver, BC, Canada

Requirements
  • Providing leadership in the characterization of antibody and other protein binding interactions including kinetics, affinity, epitope, and mechanism of action, supporting program advancement and platform development
  • Prioritizing and planning the execution of SPR, BLI, ELISA or other molecular interaction requests, as well as improving request management and communication systems
  • Coaching, mentoring, and developing talent within a growing and dynamic team
  • Stay scientifically current, driving innovation, and implementing new technologies and workflows to expand and automate the characterization of antibody binding properties, including leveraging data science and machine learning
  • Leading the development and implementation of standard operating procedures
  • Liaising with partners and communicating project updates and deliverables
  • Driving strong collaboration and communication across teams in early Discovery, Bioinformatics, Protein Engineering, Translational, and CMC
  • You are a builder who is passionate about developing innovative approaches to the discovery and development of biotherapeutics
  • You are strongly self-motivated and can identify project needs and implement solutions
  • You are enthusiastic about applying your leadership and technical expertise to revolutionize the speed and quality of antibody therapeutic discovery
  • You think critically, are curious and want to explore new technologies to improve the throughput and depth of characterizing protein binding interactions
  • You take pride in investing time to mentor team members to enhance their skills and drive career development and high performance
  • You are an outstanding communicator and teammate
  • A PhD in Biochemistry, Biophysics, Structural Biology or related field with an additional 8-10+ years of industrial or postdoctoral experience
  • Demonstrated expertise in biotherapeutic binding characterization, including deep understanding of binding kinetics, affinity, epitope, and mechanism of action, using SPR and other orthogonal methods such as BLI, ITC, ELISA, or kinexa
  • Ability to lead, mentor and support career development for a dynamic team
  • Ability to analyze large data sets and interpret and communicate data in the context of broader project objectives
  • Excellent documentation, organizational and communication skills
  • Impeccable attention to detail
  • Great interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
  • Familiarity with analytical and biophysical methods such as HPLC, light scattering, mass spectrometry, DSF, DSC would be preferred
  • Experience with the use of automation and liquid handlers would be an asset

AbCellera stands out as a leader in the biotech industry due to its unique approach to antibody drug discovery, combining expert teams, advanced technology, and data science to expedite the process from target to clinic across various therapeutic areas. The company's competitive edge lies in its ability to enable swift progress, cost reduction, and problem-solving in drug development for both innovative biotechs and leading pharmaceutical companies. Furthermore, AbCellera's commitment to technical innovation is evident in its recent presentation of new data on two T-Cell Engager Programs at SITC 2023, demonstrating its active role in advancing the field.

Company Stage

Series A

Total Funding

$393.1M

Headquarters

Vancouver, Canada

Founded

2012

Growth & Insights
Headcount

6 month growth

-3%

1 year growth

16%

2 year growth

76%
INACTIVE