Full-Time

Technical Accounting Associate Director

Technical Accounting & Compliance, R&D and Manufacturing Operations

Posted on 5/9/2026

Sarepta

Sarepta

1,001-5,000 employees

Develops gene therapies for rare diseases

Compensation Overview

$160.8k - $201k/yr

Bedford, MA, USA

Hybrid

Hybrid on-site presence at Sarepta facility required; occasional in-person events.

Category
Accounting (2)
,
Requirements
  • Bachelor’s and/or master’s degree in accounting, finance, or a related field; CPA strongly preferred
  • Four (4) to Seven (7) years of relevant experience in accounting, audit, internal controls, preferably with exposure to manufacturing or life sciences industries
  • Experience at a large audit firm preferred
  • Deep knowledge of U.S. GAAP and SOX compliance requirements
  • Strong analytical and problem-solving skills, with ability to interpret complex financial data and accounting guidance
  • Excellent communication and interpersonal skills, with a collaborative approach to cross-functional partnerships
  • Proven track record of managing external auditors and internal control remediation efforts
Responsibilities
  • Lead the development, implementation, documentation, and maintenance of SOX-compliant internal controls across R&D, Manufacturing, Supply Chain, Quality and Process Development finance related activities
  • Partner with operational leader to evaluate the financial impact of new business initiatives, systems, or process changes
  • Provide technical accounting support and documentation for areas such as cost accounting, inventory valuation, reserves, manufacturing variances, research collaborations, clinical development, and capital project expenditures
  • Research and interpret U.S. GAAP guidance for complex and non-routine transactions
  • Draft and maintain technical accounting memos, support schedules/models, sensitivity analysis, etc. that support the Company’s accounting positions
  • Provide accounting guidance on contracts, including manufacturing agreements, research and clinical agreements, inventory agreements, and the identification and accounting of ASC 842 leases embedded in these contracts
  • Drive the creation and maintenance of accounting policies and procedures to support compliance, operational readiness, and audit preparedness
  • Identify potential control deficiencies, lead remediation efforts and documentation, and contribute to a culture of continuous improvement in financial compliance
  • Monitor updates to accounting standards and assess their implications for manufacturing and technical operations
Desired Qualifications
  • Experience at a large audit firm preferred

Sarepta Therapeutics focuses on developing precision genetic medicines to treat rare diseases. It specializes in Duchenne muscular dystrophy (DMD) and is advancing gene therapies for limb-girdle muscular dystrophy (LGMD), Charcot-Marie-Tooth disease, MPS IIIA, and other CNS disorders. The company conducts research and development, carries therapies through clinical trials, and seeks regulatory approvals to bring treatments to patients, earning revenue from approved therapies and strategic partnerships. Its goal is to speed up drug development from lab research to patient treatment and to build the world’s largest gene therapy manufacturing capacity to meet global demand.

Company Size

1,001-5,000

Company Stage

IPO

Headquarters

Cambridge, Massachusetts

Founded

1980

Simplify Jobs

Simplify's Take

What believers are saying

  • Q1 2026 revenue hits $731 million, beating estimates by 56%.
  • $700 million notes refinanced to 2030, bolstering $954 million cash.
  • $600 million credit facility funds ELEVIDYS reset and pipeline advances.

What critics are saying

  • FDA denies AMONDYS 45, VYONDYS 53 conversions, slashing $228 million revenue.
  • Elevidys triggers permanent FDA restrictions after liver injuries, zeroing sales.
  • CEO Ingram retires end-2026, sparking talent exodus and pipeline delays.

What makes Sarepta unique

  • Sarepta leads DMD with PMO therapies generating $229 million in Q1 2026.
  • ELEVIDYS delivers 70-73% slower DMD progression in EMBARK Phase III trial.
  • Pipeline expands to DM1, FSHD siRNA and Huntington's trials by H1 2026.

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Benefits

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Company News

Yahoo Finance
Mar 23rd, 2026
Sarepta seeks FDA approval conversion for AMONDYS 45 and VYONDYS 53 using ESSENCE Phase 3 data

Sarepta Therapeutics has received FDA agreement to file supplemental applications by end of April seeking conversion of AMONDYS 45 and VYONDYS 53 from accelerated to traditional approvals, using data from the ESSENCE Phase 3 study and real-world evidence in Duchenne muscular dystrophy. The regulatory conversion could validate Sarepta's exon-skipping platform and strengthen its DMD franchise durability. However, the company faces ongoing safety concerns around its gene therapy ELEVIDYS. Sarepta is enrolling non-ambulant patients to test an enhanced immunosuppression regimen, with primary endpoints focused on acute liver injury incidence. The company's narrative projects $1.4 billion revenue and $171.6 million earnings by 2028, implying 17% annual revenue decline. Most optimistic analysts forecast $713.6 million earnings on $1.9 billion revenue by 2028.

Yahoo Finance
Mar 3rd, 2026
Bavarian Nordic CEO steps down amid pharma leadership shake-up

Bavarian Nordic has announced that CEO Paul Chaplin will step down after 11 years leading the Danish vaccine specialist, marking the latest executive change in pharmaceuticals this year. Chaplin, who joined in 2014, is leaving for personal reasons as his family relocates to Australia. He will remain until year-end or until a successor is found. The move follows recent departures elsewhere. Sarepta's Doug Ingram announced his retirement last month after a decade as CEO, citing family health concerns. Sanofi revealed in February it would not renew Paul Hudson's contract after six years, with share prices falling over 20% since February 2025. Belén Garijo, currently CEO of Merck KGaA, will take over at Sanofi from 29 April.

Yahoo Finance
Mar 1st, 2026
Wells Fargo cuts Sarepta Therapeutics price target to $38 from $45 after GTx launch delays

Wells Fargo has cut its price target on Sarepta Therapeutics to $38 from $45, maintaining an Overweight rating. The firm adjusted its ELEVIDYS projections, noting the gene therapy launch reset following safety events may take longer than anticipated based on 2026 guidance. However, Wells Fargo expects positive results from the company's siRNA readout. Separately, Baird reduced its price target to $20 from $22 with a Neutral rating following Sarepta's fiscal 2025 results. The company reported full-year net product revenues of $1.864 billion, comprising $965.6 million from PMO products and $898.7 million from ELEVIDYS. Sarepta Therapeutics develops RNA-targeted therapeutics and gene therapy for rare diseases, with several approved treatments for Duchenne muscular dystrophy.

Yahoo Finance
Feb 26th, 2026
Sarepta Therapeutics CEO Ingram to retire after tumultuous year for gene therapy Elevidys

Sarepta Therapeutics CEO Douglas Ingram will retire by the end of 2026 or upon appointment of his successor, the company announced in a regulatory filing. The firm has begun searching for his replacement. Ingram's departure follows a turbulent 2025 for the biotech company. Its gene therapy Elevidys, used to treat a muscle disorder, was linked to two patient deaths, prompting the FDA to request voluntary shipment halts. The company cut 500 jobs and halted development of several gene therapies. Elevidys carries the FDA's most serious safety warning and requires stringent monitoring. Despite the setbacks, Ingram said on Wednesday the therapy is on a potential pathway for expanded use. Sarepta's shares fell 82% last year and were down 4% in after-market trading. Ingram has led the company since 2017.

Yahoo Finance
Feb 26th, 2026
Sarepta posts $1.86B revenue, guides $1.2B–$1.4B for 2026 as CEO plans retirement

Sarepta Therapeutics reported 2025 net product revenue of $1.86 billion, comprising $966 million from its PMO franchise and $899 million from ELEVIDYS. The company guided 2026 approved-therapy revenue between $1.2 billion and $1.4 billion, whilst ending 2025 with $954 million in cash. Management described 2026 as a commercial "critical reset" for ELEVIDYS following two fatal events in 2025. Clinically, EMBARK three-year data showed a statistically significant 4.39-point NSAA benefit and approximately 70–73% slowing on key functional measures. Proof-of-concept readouts for DM1 and FSHD siRNA programmes are expected by end-Q1, with a Huntington's trial to begin in H1 2026. CEO Doug Ingram announced plans to retire around end-2026, with the board conducting a comprehensive successor search.