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Overview
1upHealth provides API-based data interoperability for healthcare providers, payers, and patients, enabling secure access to and exchange of health data to meet CMS interoperability rules. Its platform connects disparate health data into clients’ analytics systems, supporting individual and population health insights and regulatory compliance. The core product is a suite of API services that securely exchange health information, with revenue from subscriptions for API usage used by large healthcare organizations. Compared with competitors, 1upHealth emphasizes scalable, compliant data integration and active industry collaboration, hosting events to share best practices and shape the future of healthcare data exchange. The company’s goal is to advance healthcare digital transformation by making data exchange easier, reducing costs, and improving patient care outcomes through better data analytics and interoperability.
About 1UpHealth
Industries
Data & Analytics
Enterprise Software
Healthcare
Company Size
51-200
Company Stage
Series C
Total Funding
$76M
Headquarters
Boston, Massachusetts
Founded
2017
Simplify's Take
What believers are saying
- 1upHealth serves 75 enterprises covering 40 million patients across health plans.
- $40M Series C funding from Sixth Street Growth fuels CMS product development.
- Andrea Kowalski's appointment as CPO drives FHIR platform enhancements.
What critics are saying
- Solace Health's $130M funding erodes 1upHealth's payer market share within 12 months.
- Competitors replicate CMS-0057 APIs post-HIMSS26, commoditizing 1upHealth's lead.
- No funding since 2023 exhausts capital, forcing churn by mid-2027.
What makes 1UpHealth unique
- 1upHealth deploys all CMS-0057 APIs first, enabling compliance eight months before January 2027.
- 1upHealth's platform connects over 7500 EHR endpoints and 130 payer-patient endpoints.
- 1upHealth's lakehouse architecture standardizes clinical and claims data via FHIR APIs.
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Funding
Total Funding
$76M
Below
Industry Average
Funded Over
6 Rounds
Industry standards
Benefits
Unlimited PTO & Sick Time
Comprehensive Medical and Dental Insurance
401(k)
Paid Parental Leave
Flexible Work Location
Quarterly wellness reimbursements or monthly commuter stipend
Home office stipend
Weekly catered lunches (Boston office only)
Team lunches – Grubhub stipends every other week
Identity theft protection
Growth & Insights and Company News
6 month growth
↑ 0%1 year growth
↑ 0%2 year growth
↑ 0%Day: March 4, 2026. The countdown to CMS-0057 enforcement is on. At the HIMSS26 Global Health Conference & Exhibition, taking place March 9-12 at the Venetian Expo in Las Vegas, 1upHealth will be meeting with payer leaders who are turning regulatory requirements into a long-term interoperability strategy. Visit 1upHealth, Inc. at Booth 5253 to see how leading payers are moving [...]
Donald Rucker, MD, Chief Strategy Officer for 1upHealthPayer-provider relations are undergoing a major shift. The classic adversarial battles in the fee-for-service world are gradually giving way to capitated plans with more win-win incentives. The reality is that providers and payers famously have to live in the “two canoes” world, with one foot in volume-based revenue and the other foot in value-based revenue. As one can see, there is extraordinary information and calculation needed to optimize revenues on both sides. The good news is AI thrives in complex information landscapes where the number of variables to be considered is too large for a classic statistical model. Top areas for payers and providers to leverage AI Increasingly, the most important payment regimen to consider is Medicare Advantage (MA). MA is capitated and many of the lessons of payer-provider interactions from MA, will also likely extend into managed Medicaid. AI can support each phase of payment, including initial contracting, network design, preventative services for patients covered by the plan, actual care covered by the plan, and prior authorization.Choosing patients based on calculations optimizing CMS’s Hierarchical Condition Category classification scheme may also be impacted by AI models
LAS VEGAS, NV / ACCESS Newswire / March 3, 2025 / Today, at the 2025 Health Information Management Systems Society Conference (HIMSS25), 1upHealth, a leader in health data interoperability, announced the latest release of its 1up Platform, which introduces a modern lakehouse architecture.
1upHealth, the leading FHIR platform provider for claims & clinical data acquisition, exchange & compute, announced that Andrea Kowalski has joined its executive leadership team as the Chief Product Officer.
Award-Winning Healthcare Technology Leader to Drive Product Strategy, Scale FHIR Platform to Support Interoperability RevolutionBOSTON, MA / ACCESSWIRE / January 23, 2024 / 1upHealth, the leading FHIR® platform provider for claims & clinical data acquisition, exchange & compute, announced today that Andrea Kowalski has joined its executive leadership team as the Chief Product Officer. Kowalski will lead the company's product strategy and drive continued enhancement to 1upHealth's products, solidifying its role as the interoperability leader amid the shifting regulatory landscape and latest release of the CMS Interoperability and Prior Authorization final rule.Kowalski brings more than 15 years of experience in healthcare technology to her role at 1upHealth. Most recently, she was SVP of Products for Tebra (formerly Kareo), which offers EHR, billing, and practice management technology, where she defined product vision and strategy with a focus on acquiring and retaining customers, as well as led platform unification during a merger. Prior to that, Kowalski served as Director of Product for athenahealth, one of the largest EHR providers in the industry, where she spearheaded the development of their new products. She has also been recognized in several industry award programs, including the Top 25 Women Leaders in Healthcare Software from the Healthcare Technology Report, and the Top 25 Software Product Executives from The Software Report. She was also a founding member of Chief Boston, a private network for female executives and leaders across industries."I was immediately drawn to 1upHealth's mission to tackle one of the longstanding and complex challenges in healthcare-interoperability," said Kowalski
1UpHealth is Hiring for 3 Jobs on Simplify!
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About 1UpHealth
Industries
Data & Analytics
Enterprise Software
Healthcare
Company Size
51-200
Company Stage
Series C
Total Funding
$76M
Headquarters
Boston, Massachusetts
Founded
2017
1UpHealth is Hiring for 3 Jobs on Simplify!
Find jobs on Simplify and start your career today