A

AOA

AI-enabled platform for early cancer detection

Overview

AOA Dx develops GlycoLocate™, an AI-powered platform for early cancer detection that uses tumor marker gangliosides as biomarkers. The system analyzes data from patients to identify cancer at its earliest stages, with a focus on women’s health. The company licenses its technology to healthcare providers and institutions, enabling them to enhance diagnostic capabilities and patient care. Unlike many competitors that rely on traditional biomarkers or slower workflows, GlycoLocate™ combines data science with a novel class of biomarkers (glycolipids) to offer actionable early-detection insights. The goal is to deliver cost-effective, scalable cancer-detection technology that can be integrated into existing clinical workflows, advancing preventative care and improving outcomes.

YC Company

Work here?Claim your company

About AOA

Simplify's Rating
Why AOA is rated
C+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

Data & AnalyticsEnterprise SoftwareAI & Machine LearningHealthcare

Company Size

51-200

Company Stage

N/A

Total Funding

$31M

Headquarters

Denver, CO

Founded

2019

Get referred to AOA

See people who can refer or advise you

Simplify Jobs

Simplify's take

What believers are saying

  • AOA Dx reported 2026 AACR, ASCO, and ESMO data, sustaining scientific momentum.
  • The company raised $17 million in 2025, funding trial expansion and lab buildout.
  • Early-access preparation for AKRIVIS GD and OMIRA OC creates a near-term revenue path.

What critics are saying

  • No FDA clearance exists; a failed 2027 regulatory review would stall commercialization.
  • Clinical performance remains company-generated; independent validation in broader populations is still missing.
  • Reimbursement risk is severe: payers can reject an expensive test without proven outcome improvement.

What makes AOA unique

  • AOA Dx’s multi-omic blood test combines lipids, metabolites, proteins, and machine learning.
  • Its ovarian-cancer focus targets symptomatic women, where CA125 and imaging still miss early disease.
  • 2026 studies showed 90.2% early-stage sensitivity, differentiating it from single-biomarker competitors.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$31M

Above

Industry Average

Funded Over

6 Rounds

Notable Investors:
Convertible funding comparison data is currently unavailable. We're working to provide this information soon!
Convertible Funding Comparison Coming Soon

Benefits

  • Remote Work Options

Growth & Insights and Company News

6 month growth

0%

1 year growth

0%

2 year growth

7%
Endless Frontier Labs
Oct 29th, 2026
AOA Dx

AOA Dx is creating a liquid biopsy test that measures lipid and protein biomarkers and applies machine learning to enable early diagnosis of ovarian cancer.

PR Newswire
Oct 19th, 2026
TEAMFund releases Annual Impact Report - 144MM unique patients, 203MM patient services cumulatively and AOA Dx awarded Global Health Innovation Award - ninth consecutive female founder recipient.

TEAMFund releases Annual Impact Report - 144MM unique patients, 203MM patient services cumulatively and AOA Dx awarded Global Health Innovation Award - ninth consecutive female founder recipient. Oct 19, 2026, 08:03 ET BOSTON, Oct. 19, 2026 /PRNewswire/ - TEAMFund, a 501(c)(3) Public Charity and a For-Profit Impact Fund whose mission is to enhance patient access to medical technology in low-resource settings, announced at The AdvaMed MedTech Conference, the release of this year's Annual Impact Report. TEAMFund's seven portfolio companies (Jana Care, Forus Health, Tricog Health, MediBuddy, EchoNous, Vezeeta, Qure.ai), performed 49MM patient services and contributed to the needs of 37MM unique patients over the past year. During a presentation in Boston, Tim Ring, former C. R. Bard CEO and TEAMFund Co-Founder, said "We are proud that our companies, in aggregate, are now reaching 37MM unique patients per year, a 30% increase over last year. Impact investors today are asking for 'performance + impact,' and that was precisely the premise on which TEAMFund was founded. With Fund I now returning capital to our Limited Partners, we are seeing that health impact and investment performance can reinforce one another. These impact numbers are all about the hard work and innovation of our seven companies and their employees." Also at the MedTech Conference, TEAMFund awarded its Global Health Innovation Award to AOA Dx, which is pioneering the use of lipidomics to detect early-stage cancers through a non-invasive blood test, starting with ovarian cancer. Ovarian cancer disproportionately impacts women in low- and middle-income countries, where limited screening infrastructure, imaging, and specialist expertise mean most cases are diagnosed at advanced stages. Simple, affordable, blood-based tests can help frontline health workers screen at-risk or symptomatic women and prioritize referrals, improving early detection and outcomes without costly infrastructure. This is TEAMFund's ninth award to a female founder/CEO. A few highlights from the Annual Impact Report: *CUMULATIVELY 203MM PATIENT SERVICES AND 144MM UNIQUE PATIENTS SERVED, *67% OF PATIENTS WERE SERVED IN INDIA OR AFRICA, and *25,825 NEW PROVIDERS TRAINED LAST YEAR. A complete copy of the Report can be found on TEAMFund's website www.teamfundhealth.org. ABOUT AOA DX AOA Dx, led by CEO and Co-Founder Oriana Papin-Zoghbi, is transforming early cancer detection with a proprietary multi-omics liquid biopsy platform that integrates lipid, metabolite, and protein biomarkers with machine learning. The company's lead test, AKRIVIS GD(TM), is an investigational blood test designed to detect ovarian cancer early in symptomatic women, addressing a critical diagnostic gap in one of the deadliest cancers affecting women. AOA Dx is the ninth winner of TEAMFund's Annual Global Health Innovation Award and the ninth consecutive female founder. www.aoadx.com ABOUT TEAMFUND TEAMFund (Transforming Equity and Access in MedTech), is an organization that combines a Non-Profit with an impact fund Limited Partnership, both having a shared aim to expand access to affordable, appropriate, and sustainable medical technologies that address unmet health needs in low-resource, underserved settings across the globe. TEAMFund is co-founded and co-chaired by Timothy Ring, former Chairman and CEO of C.R. Bard, and Kathryn Gleason, former senior partner at Morgan Lewis. TEAMFund counts among its supporters over 20 major MedTech and healthcare companies worldwide. www.teamfundhealth.org SOURCE TEAMFund

Intelligence360 News
Oct 28th, 2025
AOA DX Inc. Raises $30.6M Funding

AOA DX Inc. has filed a notice with the SEC for an exempt offering of securities to raise up to $30.6 million. This filing is required under federal securities law for companies selling securities without registration under specific exemptions. The notice must be filed within 15 days of the first sale. AOA DX is focused on early-stage cancer detection for women using AI and proprietary biomarker technology.

Femtech Insider
May 5th, 2025
AOA Dx Reports High Accuracy for AI-Powered Ovarian Cancer Blood Test in 1,000 Patient Study

AOA Dx, a company developing blood-based diagnostics for early cancer detection, has demonstrated high accuracy in detecting ovarian cancer in symptomatic women using its AI-powered multi-omic platform, according to data presented at the 2025 American Association for Cancer Research Annual Meeting.

PR Newswire
Jul 31st, 2024
Colorado Bioscience Association Highlights Investment Opportunities At The 2024 Rocky Mountain Life Sciences Investor Partnering Conference

Presenting Companies Represent Transformative Technologies from the Rocky Mountain WestDENVER, July 31, 2024 /PRNewswire/ -- Colorado BioScience Association (CBSA) highlights the momentum and opportunities in Colorado's life sciences community and the greater Rocky Mountain region at the 2024 Rocky Mountain Life Sciences Investor & Partnering Conference in Breckenridge, Colorado, on September 12 and 13.Colorado BioScience AssociationThe conference aims to drive more commercialization and patient impact by attracting new funding and strategic partnerships in a region recognized as a leading hub for health innovation. CNBC covered record fundraising by Colorado's life sciences ecosystem earlier this year. In the first six months of 2024, life sciences companies and organizations raised more than $1.2 billion. Additionally, Colorado Hub for Health Impact, a national economic development campaign led by a collaboration of 22 partners, is attracting new life sciences companies, talent, and investors to Colorado.Known for its exclusive focus on life sciences, the conference will feature more than 30 pre-selected startup, emerging, and growth companies. Presenting companies are developing transformative devices, diagnostics and therapies. They are tackling cancers, drug-resistant diseases, autoimmune conditions, and women's health disparities using some of the most promising technological advancements in artificial intelligence, regenerative and personalized medicine, and synthetic biology."Colorado BioScience Association encourages investors and strategic partners to join us at the 2024 Rocky Mountain Life Sciences Investor & Partnering Conference and seize opportunities to invest in and partner with pioneering Colorado life sciences companies," said Elyse Blazevich, Colorado BioScience Association President & CEO

Recently Posted Jobs

Sign up to get curated job recommendations

AOA is Hiring for 2 Jobs on Simplify!

Find jobs on Simplify and start your career today

Don't see your dream role? Check out thousands of other roles on Simplify.Browse all jobs