B

Beacon Biosignals

EEG neurobiomarker platform for trials

Overview

Beacon Biosignals develops an EEG-based neurobiomarker platform for precision medicine in neurology and psychiatry. Its core offering provides quantitative assessments of how treatments affect EEG and sleep data to speed up clinical trials and inform dose selection. By analyzing EEG signals alongside PK/PD relationships, the platform helps identify dosing that achieves the best balance of efficacy and safety, supporting the development of new therapies. The company differentiates itself through its proprietary EEG biomarkers and a focus on integrating brain activity data into trial design, enabling closer monitoring of treatment impact for biopharma, academic medical centers, and neurotechnology developers. Beacon Biosignals aims to advance personalized treatment for neurological and psychiatric diseases and improve the efficiency of clinical development in precision medicine.

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About Beacon Biosignals

Simplify's Rating
Why Beacon Biosignals is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & AnalyticsEnterprise SoftwareAI & Machine LearningHealthcare

Company Size

51-200

Company Stage

Series B

Total Funding

$127.5M

Headquarters

Boston, Massachusetts

Founded

2019

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Simplify's Take

What believers are saying

  • April 6, 2026 Series B extension added $11 million and Samsung Next.
  • November 19, 2025 Takeda expansion promises up to $109 million in milestones.
  • December 16, 2025 Harmony deal and SLEEP 2026 data expand hypersomnia traction.

What critics are saying

  • Takeda and Harmony dominate validation; partner pullback would crush 2027 revenue visibility.
  • Beacon depends on pharma accepting EEG endpoints; failed trials kill biomarker commercialization.
  • FDA or algorithm-performance setbacks could block Waveband-driven trials and erase Beacon’s core moat.

What makes Beacon Biosignals unique

  • Beacon’s FDA-cleared Waveband enables PSG-quality at-home EEG, not consumer proxy signals.
  • Beacon’s 2025-2026 platform spans neurology, psychiatry, and sleep medicine with one dataset.
  • Beacon’s biomarker stack targets clinical endpoints and PK/PD, not only monitoring.

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Funding

Total Funding

$127.5M

Above

Industry Average

Funded Over

5 Rounds

Notable Investors:
Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Below Average

Industry standards

$35M
$30M
$45M
$65M
$100M

Benefits

  • Company Equity
  • Paid Vacation
  • Hybrid Work Options

Growth & Insights and Company News

6 month growth

0%

1 year growth

0%

2 year growth

-2%
Associated Press
Oct 22nd, 2026
Beacon Biosignals acquires Snap Diagnostics to bring EEG home sleep testing to all 50 states

Beacon Biosignals, a Boston-based neurotechnology company, has acquired Snap Diagnostics, a home sleep testing provider serving patients in all 50 US states. The deal more than doubles Beacon's patient reach and makes it one of the largest home sleep testing providers in the country. Beacon plans to offer home sleep tests that measure brain activity (EEG) from 2027, using its FDA 510(k)-cleared Waveband headband and AI analysis. Unlike wearables that estimate sleep indirectly, the headband captures sleep fragmentation linked to obstructive sleep apnea. Snap handles shipping, scoring, interpretation, and billing, so primary care and other non-sleep clinicians can order tests without in-house expertise. It will stay a subsidiary, with no change to its name or services. "Sleep happens in the brain," said chief executive officer Jacob Donoghue.

GlobeNewswire
Oct 19th, 2026
Beacon Biosignals partners with Project Sleep to shorten the path to diagnosis for people with idiopathic hypersomnia and narcolepsy.

Beacon Biosignals partners with Project Sleep to shorten the path to diagnosis for people with idiopathic hypersomnia and narcolepsy. The partnership connects Beacon's AI-driven neurotechnology with the patient-led advocacy community, expanding access to diagnosis and bringing patient voices directly into clinical research. BOSTON, Oct. 19, 2026 (GLOBE NEWSWIRE) - Beacon Biosignals today announced a partnership with Project Sleep, the patient-led nonprofit organization working to raise awareness of sleep health, sleep equity, and sleep disorders. The partnership brings together Beacon's AI-driven neurotechnology platform and Project Sleep's national community of patients, advocates, and researchers to reach people living with idiopathic hypersomnia and narcolepsy earlier in their diagnostic journeys. People with idiopathic hypersomnia (IH) wait an average of 8 to 11 years for a diagnosis, and people with narcolepsy type 1 (NT1) wait 4 to 11 years (Zhang, 2025). During that time, patients are often misdiagnosed with major depressive disorder (MDD) or another psychiatric condition, or the picture is clouded by a diagnosis of obstructive sleep apnea (OSA). These diagnostic delays can have a severely detrimental impact on patients' education, employment, and quality of life. Beacon develops at-home diagnostics and clinical trial technology designed to target that gap directly. Through this partnership, the two organizations will identify undiagnosed patients, support people already diagnosed with better treatment pathways, and shorten the time between a first symptom and a clinical answer. "Improving patients' lives is central to Beacon's mission," says Jacob Donoghue, MD, PhD, and CEO of Beacon Biosignals. "Project Sleep has spent more than a decade building trust in this community and amplifying patient voices. Working alongside them enables us to use our technology to find and treat people with disorders of hypersomnia sooner." With Project Sleep, Beacon will run patient focus groups, giving the company structured input from patients and caregivers on the testing experience, and informing Beacon's national home sleep testing network. That network supports enrollment in clinical research, where Project Sleep plays a central role by connecting its community to sleep disorder studies from both industry and academic sponsors. "Our community has always been ready to participate in research and to help solve the diagnostic delay that so many of us lived through," adds Julie Flygare, JD, President and CEO of Project Sleep. "What has been missing is a way to relay those insights to the people building diagnostic tools and novel therapeutics. This partnership creates that link, and it treats patients as contributors rather than subjects." Founded in 2013 by Julie Flygare, who was diagnosed with narcolepsy at age 24, Project Sleep is one of the few sleep organizations led by someone living with the condition it serves. Its programs include the Sleep Helpline, a free national helpline for people facing sleep issues; Rising Voices, which has trained more than 190 patient advocates across 21 countries; and the Jack and Julie Narcolepsy Scholarship, the first national scholarship program for students with narcolepsy and idiopathic hypersomnia. Beacon and Project Sleep will begin joint work immediately, with Beacon participating in Project Sleep's 7th annual Sleep Advocacy Forum on October 26, 2026, in Washington, D.C. Learn more about Beacon Biosignals at www.beacon.bio. About Beacon Biosignals Beacon Biosignals is transforming precision medicine for the brain. Our FDA-cleared, at-home Waveband EEG and cardiopulmonary devices deliver gold-standard sleep diagnostics in patients' natural environments. The Beacon Platform applies AI/ML to stratify patients and generate clinically validated endpoints for interventional clinical trials, and tracks disease progression of neurodegenerative, neuropsychiatric, and primary sleep disorders in longitudinal and open label studies. We partner with leading pharmaceutical, biotechnology companies, and health systems across CNS disease in service of building the world's largest library of clinical and physiology data supporting scientific discovery and patient care. About Project Sleep Project Sleep is a 501(c)(3) nonprofit organization dedicated to raising awareness about sleep health, sleep equity, and sleep disorders. Founded in 2013, the organization educates and empowers individuals through events, campaigns, and programs that bring people together to talk about sleep as a pillar of health. Project Sleep holds a four-star rating from Charity Navigator and a Platinum Seal of Transparency from Candid, and is a member of the National Organization for Rare Disorders. Learn more at project-sleep.com. Media Contact Beacon Biosignals Isabella Lazzareschi, Director of Marketing [email protected]

Longevity.Technology
Jun 22nd, 2026
Beacon Biosignals showcases advanced AI sleep tech and clinical data at SLEEP 2026.

Beacon Biosignals showcases advanced AI sleep tech and clinical data at SLEEP 2026. Beacon Biosignals participated in SLEEP 2026, engaging clinicians, researchers and sleep medicine leaders. The company highlighted multiple presentations focused on automated sleep staging algorithms, machine learning-based arousal detection and a large-scale EEG foundation model designed for multi-device sleep analytics. Beacon also presented validation data for its Waveband device in hypersomnia disorders, developed in collaboration with Takeda and featured in an oral presentation, according to the company. For investors, the activity suggests ongoing progress toward building clinically relevant evidence around Beacon's digital biomarker and EEG analytics platform that could support future commercialization or partnership opportunities in sleep medicine and neurology. The emphasis on expert-level algorithm performance and large-scale EEG models indicates an effort to differentiate through technical depth and scalability, potentially positioning the business to serve biopharma trials and clinical endpoints. The company also promoted meeting availability at the conference as part of its business development outreach.

Simcast
Apr 20th, 2026
Beacon Biosignals targets neurology trial partners with fda-cleared Waveband EEG at AAN 2026.

Beacon Biosignals targets neurology trial partners with fda-cleared Waveband EEG at AAN 2026. Last updated: April 20, 2026 Beacon Biosignals is participating in the 2026 American Academy of Neurology Annual Meeting in Chicago. The company is showcasing its Waveband device, a novel technology for electroencephalogram (EEG) signal acquisition and analysis. This event marks a significant opportunity for the company to present its advancements in brain signal technology to a key audience of neurologists and researchers. * Beacon Biosignals' Waveband device is designed for advanced EEG signal acquisition and analysis. The device aims to provide more accurate and efficient data collection for neurological studies. The company's presence at the American Academy of Neurology Annual Meeting signifies its commitment to developing and promoting innovative solutions in the field of neurology. This participation allows for direct engagement with medical professionals and potential collaborators. The meeting is a premier event for showcasing the latest research and technologies in neurology.

FinSMEs
Apr 6th, 2026
Beacon Biosignals raises $11M; brings Series B financing to over $97M.

Beacon Biosignals raises $11M; brings Series B financing to over $97M. April 6, 2026 Beacon Biosignals, a Boston, MA-based company leveraging brain data to advance human health, raised an $11m extension to its Series B financing, bringing the funding round to $97m the cumulative funding to over $132m. The upsized round included new investors JSL Health, Palo Santo VC, Kicker Ventures, and Samsung Next. This financing builds on Beacon's previously announced $86m Series B, led by a syndicate of leading healthcare and technology investors, including Innoviva, GV (Google Ventures), S32, Catalio Capital Management, General Catalyst, Logos Capital, Casdin Capital, Indicator Ventures and others. The company intends to use the funds to further accelerate its mission to transform brain health through scalable, at-home EEG and advanced analytics, powering the next generation of diagnostics, clinical trials, and precision medicine. Led by Jacob Donoghue, CEO, Beacon Biosignals combines FDA-cleared wearable EEG technology with advanced AI to capture and analyze real-world neural data, enabling breakthroughs across neurology, psychiatry, and sleep medicine. The platform provides clinicians and biopharma partners with objective measures of brain function that accelerate research, improve diagnostics, and guide new treatments. 06/06/2026

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