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Bitterroot Bio

Develops immunotherapies for cardiovascular disease

Overview

Bitterroot Bio develops therapies that use the body's immune system to treat heart diseases, focusing on cardio-immunology and conditions like atherosclerosis. Its products are immunotherapies designed to address root causes by modulating immune cells and inflammation rather than only alleviating symptoms. The company works with cardiologists to test and ensure safety and efficacy, delivering treatments that aim to reduce arterial inflammation and plaque progression. Compared to traditional cardiovascular drugs that target symptoms or risk factors, Bitterroot Bio targets the immune-system-driven causes of disease, potentially offering a new way to prevent or slow heart-related inflammation. The goal is to provide immune-based treatments that help patients fight cardiovascular diseases at their source, improving outcomes for those with inflammatory heart conditions.

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About Bitterroot Bio

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Industries

BiotechnologyHealthcare

Company Size

11-50

Company Stage

Series A

Total Funding

$145M

Headquarters

Palo Alto, CA

Founded

2021

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Funding

Total Funding

$145M

Above

Industry Average

Funded Over

1 Rounds

Series A funding typically happens when a startup has a product and some customers, and now needs funding to scale. This money is usually used to grow the team, expand marketing, and improve the product. Venture capital firms are frequently the main investors here.
Series A Funding Comparison
Above Average

Industry standards

$15M
$8.2M
$15M
$30M
$145M

Growth & Insights and Company News

6 month growth

-3%

1 year growth

0%

2 year growth

4%
Midwest Region Biotech Networks
Mar 17th, 2025
Bitterroot Bio to Present Detailed Results from Phase 1 Study of BRB-002 at American College of Cardiology Annual Scientific Session 2025

Bitterroot Bio to present detailed results from Phase 1 study of BRB-002 at American College of Cardiology Annual Scientific Session 2025.

MM+M
Jun 6th, 2024
The Escalator: Eli Lilly, Takeda, Illumina and more

Bitterroot Bio appointed Georgette Verdin as chief people officer and Sherwin Chen as chief legal officer and corporate secretary.

ForexTV
Feb 27th, 2024
Bitterroot Bio and Biotheus Announce Research Collaboration to Develop Bispecific Proteins in Cardio-Immunology

Bitterroot Bio and Biotheus announce research collaboration to develop bispecific proteins in cardio-immunology.

BioSpace
Jan 3rd, 2024
Nextgen Class Of 2024: Top Life Sciences Startups To Watch This Year

Pictured: Map of NextGen Class of 2024/BioSpaceBioSpace is proud to present its NextGen Bio Class of 2024, a list of the hottest new life sciences companies in the United States. To come up with this list, BioSpace identified companies that launched between September 2022 and September 2023 with Series A funding. They were then assessed using several different criteria including finance, partnerships, pipeline, growth potential and innovation. After awarding points for each category, the BioSpace editorial team ranked its top 30. The impressive group of startups that make up BioSpace’s NextGen Class of 2024 is already making an impact on the industry. We will continue to keep a close eye on these companies as we move into the new year. Launched: March 2023Location: Boston, MA, and San Diego, CASeries A: $100MSeries B: $150MNotable: Good rapport won this startup top billing on our list. The product of a partnership between Third Rock Ventures and Janssen Neuroscience, Rapport’s first program focuses on targeting drug-resistant seizure disorders and is in Phase I development.Differentiator: Specificity is what sets Rapport apart, according to CEO Abe Ceesay, who spoke with BioSpace in March 2023

The Business Journals
Jun 8th, 2023
Daily Digest: Big Porsche hub opens in S.F.; Biotechs ink new leases

Bitterroot Bio, a Palo Alto-based developer of immunotherapies for cardiovascular disease, raised $145 million in Series A funding co-led by Arch Venture Partners and Deerfield Management.

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