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Overview
C the Signs uses artificial intelligence to help healthcare professionals detect cancer earlier by analyzing patient symptoms, clinical data, and risk factors in real time to suggest diagnostic and referral pathways. It integrates into primary care and broader health system workflows, translating complex cancer guidelines into practical decisions across all cancer types, including rare ones. The platform supports faster referrals, reduces diagnostic delays, and enables more personalized cancer care while focusing on population health to identify disparities and align with national targets. Its goal is to improve patient outcomes by enabling earlier diagnosis and scalable, data-driven cancer care across health systems.
About C the Signs
Industries
Data & Analytics
Enterprise Software
AI & Machine Learning
Healthcare
Company Size
11-50
Company Stage
Early VC
Total Funding
$14.7M
Headquarters
London, United Kingdom
Founded
2017
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Simplify's Take
What believers are saying
- March 2026 Essex pathway expands C the Signs across high-miss upper GI cancers.
- January 2026 NHS news showed Northamptonshire ICB rolling C the Signs into every GP practice.
- $8 million Khosla-backed U.S. expansion funds American commercialization and regulatory adaptation.
What critics are saying
- NHS procurement concentration makes one stalled ICB rollout damage revenue immediately.
- A negative NHS randomized evaluation would freeze national expansion and kill U.S. sales.
- Epic, Cerner, and diagnostics vendors can bundle similar triage, compressing margins.
What makes C the Signs unique
- UKCA-marked, NHS-born workflow embeds cancer triage directly into primary care.
- North East Essex launched England's first AI case-finding pathway for oesophageal and gastric cancers.
- Independent evaluation tied Suffolk and North East Essex deployment to 272 earlier diagnoses.
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Funding
Total Funding
$14.7M
Meets
Industry Average
Funded Over
3 Rounds
Benefits
Stock Options
Flexible Work Hours
Hybrid Work Options
Remote Work Options
Health Insurance
Dental Insurance
Vision Insurance
401(k) Retirement Plan
Life Insurance
Paid Vacation
Paid Sick Leave
Paid Holidays
Growth & Insights and Company News
6 month growth
↓ -2%1 year growth
↓ -2%2 year growth
↓ -2%A UK-first, AI-enabled pathway has launched in North East Essex to improve early detection of oesophageal and stomach cancers, which are among England's hardest cancers to diagnose early. Around four in five cases are currently diagnosed at advanced stages. Delivered by AstraZeneca, C the Signs, NHS Suffolk and North East Essex ICB, Health Innovation East and GP Primary Choice, the programme uses AI to analyse electronic health records and identify at-risk patients. Eligible patients receive SMS invitations to complete digital assessments, with high-risk cases triaged to appropriate diagnostics including capsule sponge testing or endoscopy. C the Signs already supports over 1,500 GP practices across England. The programme aligns with the National Cancer Plan's ambition to shift from reactive to predictive, risk-based approaches for cancers without established screening programmes.
C the Signs, a London, UK-based creator of an Artificial Intelligence (AI)-based platform to identify patients at risk of cancer at the earliest and most curable stage, raised $8M in funding
C the Signs, an AI-powered cancer detection company, raised $8M in a funding round led by Khosla Ventures to expand from the UK to the US. The company's platform analyzes EHRs to identify cancer risk early, improving survival rates. In the UK, it identified 20.7% of breast cancer cases up to five years earlier and improved early-stage ovarian cancer diagnosis by 53.3%. The funding aims to enhance early detection and personalized care in the US healthcare system.
C the Signs is Hiring for 8 Jobs on Simplify!
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About C the Signs
Industries
Data & Analytics
Enterprise Software
AI & Machine Learning
Healthcare
Company Size
11-50
Company Stage
Early VC
Total Funding
$14.7M
Headquarters
London, United Kingdom
Founded
2017
C the Signs is Hiring for 8 Jobs on Simplify!
Find jobs on Simplify and start your career today