CRIO

CRIO

Enterprise clinical trial data capture platform

Overview

CRIO provides an integrated health tech platform for clinical trials, unifying data capture and regulatory workflows through eSource that feeds directly into electronic data capture (EDC) for remote monitoring and real-time data review. It captures data once at a single point and uses autofill and data validation to reduce protocol deviations and avoid re-entry, while offering modules like patient scheduling, recruitment, and financial management. Its differentiators include leadership in eSource, a single platform that serves both sites and sponsor organizations, and built-in compliance with 21 CFR 11, ICH-GCP, GDPR, and HIPAA. CRIO’s goal is to improve the quality and speed of trials and enable patient-centric data access from anywhere, so trials can be conducted where patients are.

About CRIO

Simplify's Rating
Why CRIO is rated
B
Rated B on Competitive Edge
Rated A on Growth Potential
Rated C on Differentiation

Industries

Company Size

51-200

Company Stage

Late Stage VC

Total Funding

$19M

Headquarters

Boston, Massachusetts

Founded

2015

Get referred to CRIO

See people who can refer or advise you

Simplify Jobs

Simplify's Take

What believers are saying

  • Revenue grew nearly 50% year over year in Q1 2026.
  • Lightship selected CRIO in February 2026 for scalable site-network execution.
  • CRIO launched AI-ready analytics and language expansion during 2026 product acceleration.

What critics are saying

  • Medidata can commoditize CRIO if customers adopt its native workflow stack.
  • Riverside's 2024 control brings acquisition pressure if growth stalls before 2027.
  • CRIO's 51-200 person team faces execution risk as integrations multiply globally.

What makes CRIO unique

  • CRIO powers eSource, CTMS, and regulatory workflows for site-centric trials.
  • Medidata integrated CRIO in March 2026 across 2,500 sites and 30 countries.
  • CRIO still serves sponsors, CROs, and sites through plug-and-play integrations.

Help us improve and share your feedback! Did you find this helpful?

Funding

Total Funding

$19M

Below

Industry Average

Funded Over

6 Rounds

Late VC funding comparison data is currently unavailable. We're working to provide this information soon!
Late VC Funding Comparison
Coming Soon

Benefits

Remote Work Options

Unlimited Paid Time Off

401(k) Company Match

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Professional Development Budget

Home Office Stipend

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

-1%

2 year growth

-2%
PR Newswire
Jan 21st, 2026
CRIO partners with Todata to offer clinical research sites real-time performance analytics

CRIO, a leader in eSource technology for clinical research, has partnered with Todata Analytics to integrate SiteGrades as an analytics solution within CRIO's Partners Programme. The collaboration enables clinical research sites to access real-time performance dashboards without per-user fees or technical implementation requirements. SiteGrades provides sites with dashboards tracking enrollment performance, exam room utilisation and financial metrics. The platform can connect financial systems, HR platforms and other data sources to deliver comprehensive operational insights. It includes Tod AI, Todata's compliant artificial intelligence layer, allowing teams to query complex data instantly. CRIO customers can access the integration immediately. Both platforms operate within HIPAA-compliant frameworks. CRIO has been providing eSource technology since 2015, whilst Todata Analytics was founded in 2017.

Business Wire
May 21st, 2024
CRIO Secures Major Investment for Expansion

CRIO, Inc., a leading provider of eSource and eClinical technologies, has received a significant investment from The Riverside Company, a global private equity firm. This investment will support CRIO's continued expansion and enhancement of its eClinical platform, which streamlines clinical trial processes and improves data quality. Co-CEOs Raymond Nomizu and Jonathan Andrus highlighted the benefits of Riverside's financial support and industry expertise in achieving CRIO's goals.

Climedo
Mar 11th, 2024
Trial Physician Survey: Status Quo in Clinical Research

In the fall of 2023, Climedo Health GmbH collaborated with Siteworks Clinical Research to conduct a survey aiming to understand trial physicians' perspectives on clinical trials and capture the current state of clinical research.

PR Newswire
Nov 28th, 2023
Are Regulators Driving Or Impeding Innovation In Clinical Trials? Upcoming Webinar Hosted By Xtalks

Internal quality assurance (QA) and regulatory teams can be a hold-up when they rely on historical practices and personal preference rather than current regulatory guidance in assessing the feasibility and risks of implementing new and innovative solutions to clinical trial challenges. .

Yahoo Finance
Nov 14th, 2023
SDC Announces Partnership with CRIO on eSource Initiative

SDC announces partnership with CRIO on eSource initiative.

Recently Posted Jobs

Sign up to get curated job recommendations

CRIO is Hiring for 9 Jobs on Simplify!

Find jobs on Simplify and start your career today

Don't see your dream role? Check out thousands of other roles on Simplify. Browse all jobs →