C

Casdin Capital

Venture investor financing next-gen life sciences

Overview

Casdin Capital is a venture investor focused on funding next-generation life science innovation. It finances early-stage and growth-stage biotech companies, particularly in areas like gene therapy, cancer, rare diseases, and industrial biotechnology, to help bring new therapies and biotechnologies to market. Its product is capital and strategic support for life science startups; as investors, they provide funding, guidance, and connections to advance scientific breakthroughs into products. Casdin differentiates itself by concentrating on cutting-edge biology and genome-focused therapies, leveraging expertise in biotechnology and policy to guide portfolio companies and navigate regulatory and market landscapes. The company’s goal is to accelerate the development and commercialization of transformative biotechnologies that can improve health and biotech outcomes.

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About Casdin Capital

Simplify's Rating
Why Casdin Capital is rated
C
Rated C on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

Financial ServicesBiotechnology

Company Size

51-200

Company Stage

N/A

Total Funding

$20.5B

Headquarters

New York City, New York

Founded

2012

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Simplify's take

What believers are saying

  • Casdin stayed active in 2026, backing Atrium Therapeutics, Multiply Labs, and Flare.
  • Dealroom logged 216 investments and 75 exits, signaling enduring sourcing and liquidity.
  • Casdin kept buying GeneDx in June 2026 despite a 67% stock collapse.

What critics are saying

  • Casdin’s identity depends on Eli Casdin; succession risk is immediate and existential.
  • GeneDx exposure creates conflicts and headline risk when portfolio company stock swings sharply.
  • Biotech concentration leaves Casdin exposed if 2026-2027 financing markets shut and exits stall.

What makes Casdin Capital unique

  • Eli Casdin blends hedge-fund trading with venture investing across genomics, oncology, and tools.
  • Casdin’s board access shows up in GeneDx, where Eli Casdin joined since 2021.
  • The firm repeatedly backs platform biology companies, not generic software or healthcare services.

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Funding

Total Funding

$20.5B

Above

Industry Average

Funded Over

0 Rounds

Company News

U.S. Securities and Exchange Commission
Nov 12th, 2026
Form 8-K

Date of Report (Date of earliest event reported): October 15, 2021

DNA Script
Nov 5th, 2026
DNA Script Raises $165M in Oversubscribed Series C Financing to Accelerate Commercialization of Enzymatic DNA Printing Platform | DNA Script

New Funding, Targeted to Accelerate Application Expansion and Platform Commercialization, Brings Total Amount Raised to Date to $280M DNA Script, a pioneer in Enzymatic DNA Synthesis (EDS) and DNA printing...

U.S. Securities and Exchange Commission
Oct 25th, 2026
EDGAR Filing Documents for 0001886216-21-000001

EIN.: 834307023 | State of Incorp.: DE | Fiscal Year End: 1231Type: D | Act: 33 | File No.: 021-415565 | Film No.: 211302465

MarketScreener
Oct 23rd, 2026
Bolt Biotherapeutics secures $120M from investors including a16z and Deep Track Capital

Bolt Biotherapeutics expects to raise about $120 million from a group of healthcare investors. It signed a Securities Purchase Agreement for 13,995.311 shares of Series D Non-Voting Convertible Preferred Stock at $8,574.30 each, for gross proceeds of $119,999,995. Investors include Deep Track Capital, ADAR1 Capital, Andreessen Horowitz, LYFE Capital, Coastlands Capital, Eventide Asset Management, Casdin Capital, Curie.Bio, SilverArc Capital, Soleus Capital, and Deviation Capital. The deal also includes warrants to buy up to 6,997,655 common shares at an exercise price of $8.5743 per share on an as-converted basis. Each Series D share converts into 1,000 common shares, subject to conditions. The financing is expected to close on October 26, 2026.

Multiply Labs
Oct 15th, 2026
Multiply Labs Raises $75 Million Series B | Multiply Labs

Series B funding will strengthen Multiply Labs’ momentum scaling the robotic manufacturing platform turning AI-discovered drugs into treatments patients can receive.

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