C

Celldex Therapeutics

Develops antibody-based therapies targeting inflammatory diseases

Overview

Celldex Therapeutics develops antibody-based therapies for inflammatory, allergic, and autoimmune diseases, focusing on mast cell biology. Its lead program barzolvolimab is a humanized monoclonal antibody that inhibits KIT, reducing mast cell activity and inflammation; its pipeline includes other antibodies designed to engage the immune system or modulate disease pathways. The company leverages partnerships and licensing in addition to developing its own therapies to create a breadth of programs in its target areas. Its goal is to deliver therapies that lessen inflammation and autoimmune activity by targeting mast cells and related signaling pathways.

Significant Headcount Growth

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About Celldex Therapeutics

Simplify's Rating
Why Celldex Therapeutics is rated
C+
Rated B on Competitive Edge
Rated B on Growth Potential
Rated D+ on Differentiation

Industries

BiotechnologyHealthcare

Company Size

201-500

Company Stage

IPO

Headquarters

Hampton, NJ

Founded

1983

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What believers are saying

  • Celldex met all primary and key secondary endpoints in EMBARQ-CSU1 and CSU2.
  • Management expects a 2027 BLA submission and continued 52-week data through 2026.
  • Celldex has no commercial sales burden while development capital stays deployable.

What critics are saying

  • Celldex lost $227.7 million in nine months, forcing more dilution risk soon.
  • Purcell & Lefkowitz opened a shareholder investigation on Oct. 12, 2026.
  • If barzolvolimab misses approval, Celldex becomes a cash-burning shell.

What makes Celldex Therapeutics unique

  • Barzolvolimab produced best-in-disease Phase 3 CSU results on Nov. 5, 2026.
  • Celldex owns a mast-cell biology platform, not a single-indication antibody program.
  • EMBARQ-CSU1, EMBARQ-CSU2, ColdU, and SD create multiple near-term readouts.

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Funding

Total Funding

$1.2B

Above

Industry Average

Funded Over

7 Rounds

Post IPO Equity funding comparison data is currently unavailable. We're working to provide this information soon!
Post IPO Equity Funding Comparison Coming Soon

Benefits

  • Health Insurance
  • Paid Holidays
  • Paid Vacation
  • Paid Sick Leave
  • 401(k) Retirement Plan

Stock Price

Growth & Insights and Company News

6 month growth

14%

1 year growth

13%

2 year growth

13%
Yahoo Finance
Nov 6th, 2026
Celldex posts $75.56M Q3 net loss and files universal shelf registration

Celldex Therapeutics reported a third-quarter 2026 net loss of $75.56 million, or $0.96 per share. It also filed a universal shelf registration covering common and preferred stock, warrants, depositary shares, and units. The nine-month net loss reached $227.75 million, or $3.06 per share, against revenue of just $0.037 million. The biotech is still pre-commercial and relies heavily on barzolvolimab and its mast cell programme. The shelf lets Celldex raise cash if trials, commercial build-out, or manufacturing need more funding. It also keeps the risk of shareholder dilution in play. Analysts' forecasts vary widely: the most cautious expect $15.5 million in revenue by 2029, while the consensus view points to $311.0 million.

The Cerbat Gem
Nov 2nd, 2026
Celldex Therapeutics (CLDX) projected to release quarterly earnings on Monday.

Celldex Therapeutics (CLDX) projected to release quarterly earnings on Monday. Posted by Scott Moore on Nov 2nd, 2026 Celldex Therapeutics (NASDAQ:CLDX - Get Free Report) is expected to be releasing its Q3 2026 results after the market closes on Monday, November 9th. Analysts expect Celldex Therapeutics to post earnings of ($1.02) per share and revenue of $0.72 million for the quarter. Interested persons can find conference call details on the company's upcoming Q3 2026 earnings summary page for the latest details on the call scheduled for Monday, November 9, 2026 at 4:00 PM ET. Celldex Therapeutics (NASDAQ:CLDX - Get Free Report) last released its earnings results on Thursday, August 6th. The biopharmaceutical company reported ($0.94) earnings per share for the quarter, beating the consensus estimate of ($1.06) by $0.12. The firm had revenue of $0.02 million during the quarter, compared to analysts' expectations of $0.73 million. On average, analysts expect Celldex Therapeutics to post ($4.17) EPS for the current fiscal year and ($4.29) EPS for the next fiscal year. Celldex Therapeutics trading down 0.6%. NASDAQ:CLDX opened at $29.93 on Monday. Celldex Therapeutics has a twelve month low of $22.10 and a twelve month high of $45.14. The company has a market cap of $2.35 billion, a P/E ratio of -6.92 and a beta of 1.04. The company's 50-day moving average price is $34.06 and its 200-day moving average price is $32.58. Analyst ratings changes. A number of research firms have commented on CLDX. Wall Street Zen upgraded Celldex Therapeutics from a "strong sell" rating to a "sell" rating in a research report on Sunday, July 12th. Guggenheim upped their price target on Celldex Therapeutics from $90.00 to $100.00 and gave the company a "buy" rating in a report on Monday, July 20th. Cantor Fitzgerald lifted their price target on Celldex Therapeutics from $61.00 to $72.00 and gave the stock an "overweight" rating in a research report on Tuesday, September 22nd. Wells Fargo & Company lifted their target price on Celldex Therapeutics from $48.00 to $72.00 and gave the company an "overweight" rating in a research note on Wednesday, July 29th. Finally, Barclays raised their target price on Celldex Therapeutics from $48.00 to $53.00 and gave the company an "overweight" rating in a report on Friday, August 7th. Eleven equities research analysts have rated the stock with a Buy rating, one has issued a Hold rating and one has given a Sell rating to the stock. Based on data from MarketBeat.com, the company currently has a consensus rating of "Moderate Buy" and a consensus target price of $63.08. About Celldex Therapeutics. Celldex Therapeutics, Inc is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing targeted therapeutics for diseases with significant unmet medical needs. The company uses antibody-based technologies to develop treatments intended to modulate the immune system and address inflammatory, autoimmune and other serious conditions. Celldex's lead investigational product is barzolvolimab, an antibody designed to selectively block the KIT receptor and reduce mast-cell activity. Further reading. Receive News & Ratings for Celldex Therapeutics Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Celldex Therapeutics and related companies with MarketBeat.com's FREE daily email newsletter.

Financial Modeling Prep
Sep 23rd, 2026
Celldex Therapeutics (NASDAQ: CLDX) Price Target Soars on Positive Phase III clinical trial results.

Celldex Therapeutics (NASDAQ: CLDX) Price Target Soars on Positive Phase III clinical trial results. Sep 23, 2026 Market News FMPCelldex Therapeutics (NASDAQ: CLDX) Price Target Soars on Positive Phase III Cli... * Leerink Partners significantly raised its price target for Celldex Therapeutics to $88.00, indicating strong analyst confidence in the biotechnology stock. * Celldex reported successful Phase III clinical trial results for its drug barzolvolimab in treating chronic spontaneous urticaria (CSU), meeting all primary endpoints. * Despite the positive news regarding CSU, the Celldex stock price experienced a slight decline following the discontinuation of a separate Phase 2 trial for barzolvolimab in another condition. Celldex Therapeutics (NASDAQ: CLDX) is a leading biotechnology stock that develops innovative therapies to treat specific diseases. With a market capitalization of around $2.1 billion, the company focuses on creating targeted treatments through advanced drug development. Its main drug candidate is barzolvolimab, which is being studied for several conditions. On September 23, 2026, Thomas Smith of Leerink Partners increased the price target for Celldex Therapeutics to $88.00 from $70.00. A price target is an analyst's projection of a stock's future price, crucial for stock analysis. At the time, the stock was trading at $31.19, showing significant potential upside according to the analyst. This optimism follows positive results from Celldex's Phase III clinical trials for barzolvolimab. The drug is designed for adults with chronic spontaneous urticaria (CSU), a skin condition, who do not get better with antihistamines. The studies, EMBARQ-CSU1 and EMBARQ-CSU2, met all their main goals, highlighting progress in CSU treatment. The trials showed that barzolvolimab was effective and that its benefits lasted or even improved over 24 weeks. As highlighted by Defense World, these global trials included 1,939 patients. Celldex now plans to submit a Biologics License Application (BLA) in 2027, a key step towards potential FDA approval for the new drug. However, as reported by Benzinga, Celldex also stopped a separate Phase 2 trial of barzolvolimab for a different condition after it failed to meet its goals. Despite the positive CSU news, the Celldex stock price decreased by 6.03% to $31.49 during the day's trading. Market news and analyst rating coverage Andrew Wynn writes market news and analyst-rating coverage for the FMP blog, tracking price-target revisions, broker upgrades and downgrades, and earnings developments across U.S. equities. His posts distill fast-moving market events into clear, factual summaries grounded in financial data. Financial data for every need. Real-time quotes and 30+ years of historical data, including prices, fundamentals, and insider transactions - all accessible via API. Stock Screener 2017-2026 (C) FMP

MarketBeat
Sep 10th, 2026
Celldex Therapeutics (NASDAQ:CLDX) given new $50.00 price target at Morgan Stanley.

Celldex Therapeutics (NASDAQ:CLDX) given new $50.00 price target at Morgan Stanley. September 10, 2026 Key points. * Morgan Stanley raised its price target for Celldex Therapeutics to $50 from $46 and maintained an "overweight" rating, implying approximately 29.5% upside from the prior close. * Analyst sentiment is broadly positive: Celldex has a consensus "Moderate Buy" rating and an average price target of $56.42, although targets range widely from $42 to $100. * Shares fell 0.4% to $38.62 in Thursday trading. Celldex recently reported a quarterly loss of $0.94 per share, which was better than the expected $1.06 loss, but revenue of $0.02 million came in below expectations. * Five stocks we like better than Celldex Therapeutics. Celldex Therapeutics (NASDAQ:CLDX - Get Free Report) had its target price lifted by Morgan Stanley from $46.00 to $50.00 in a research note issued on Thursday, Benzinga reports. The brokerage currently has an "overweight" rating on the biopharmaceutical company's stock. Morgan Stanley's price target points to a potential upside of 29.48% from the company's previous close. Several other analysts have also recently weighed in on the stock. Wall Street Zen raised shares of Celldex Therapeutics from a "strong sell" rating to a "sell" rating in a report on Sunday, July 12th. HC Wainwright reiterated a "buy" rating and set a $42.00 price target on shares of Celldex Therapeutics in a report on Monday, June 15th. Cantor Fitzgerald dropped their price objective on shares of Celldex Therapeutics from $67.00 to $61.00 and set an "overweight" rating on the stock in a research report on Wednesday, July 22nd. Guggenheim raised their price objective on shares of Celldex Therapeutics from $90.00 to $100.00 and gave the company a "buy" rating in a report on Monday, July 20th. Finally, UBS Group lifted their price objective on shares of Celldex Therapeutics from $38.00 to $45.00 and gave the stock a "buy" rating in a research report on Wednesday, June 10th. One investment analyst has rated the stock with a Strong Buy rating, ten have given a Buy rating, one has issued a Hold rating and one has issued a Sell rating to the company. According to data from MarketBeat, Celldex Therapeutics has a consensus rating of "Moderate Buy" and a consensus price target of $56.42. Celldex Therapeutics trading down 0.4%. NASDAQ:CLDX traded down $0.17 during midday trading on Thursday, reaching $38.62. The company had a trading volume of 221,694 shares, compared to its average volume of 931,862. Celldex Therapeutics has a 12-month low of $22.10 and a 12-month high of $45.14. The firm has a market capitalization of $3.03 billion, a price-to-earnings ratio of -8.88 and a beta of 0.84. The stock's fifty day simple moving average is $39.19 and its 200-day simple moving average is $34.22. Discover more Stock split calculator Stock profit calculator Stock market news Celldex Therapeutics (NASDAQ:CLDX - Get Free Report) last issued its quarterly earnings results on Thursday, August 6th. The biopharmaceutical company reported ($0.94) earnings per share for the quarter, topping the consensus estimate of ($1.06) by $0.12. The company had revenue of $0.02 million for the quarter, compared to analysts' expectations of $0.73 million. As a group, sell-side analysts expect that Celldex Therapeutics will post -4.17 EPS for the current year. Hedge funds weigh in on Celldex Therapeutics. Hedge funds have recently added to or reduced their stakes in the stock. Wilmington Savings Fund Society FSB acquired a new position in shares of Celldex Therapeutics in the 3rd quarter valued at $42,000. Russell Investments Group Ltd. raised its stake in Celldex Therapeutics by 27.6% during the 2nd quarter. Russell Investments Group Ltd. now owns 2,315 shares of the biopharmaceutical company's stock worth $47,000 after acquiring an additional 501 shares in the last quarter. Quantbot Technologies LP acquired a new stake in Celldex Therapeutics during the 3rd quarter worth $63,000. Nykredit A S purchased a new stake in Celldex Therapeutics in the second quarter valued at $67,000. Finally, Kestra Advisory Services LLC acquired a new position in Celldex Therapeutics in the fourth quarter valued at $98,000. Celldex Therapeutics company profile. Celldex Therapeutics, Inc is a clinical-stage biopharmaceutical company focused on the discovery and development of targeted immunotherapies for cancer and other serious diseases. The company's research platforms leverage novel antibody and vaccine technologies designed to engage the patient's immune system, with a particular emphasis on oncology and neurologic indications. Celldex's pipeline includes both monoclonal antibodies and biologic agents that seek to modulate immune responses or deliver targeted cytotoxic activity. Among Celldex's lead product candidates is glembatumumab vedotin, an antibody-drug conjugate directed against the glycoprotein NMB (gpNMB) for the treatment of certain breast and skin cancers. This instant news alert was generated by narrative science technology and financial data from MarketBeat in order to provide readers with the fastest reporting and unbiased coverage. Please send any questions or comments about this story to [email protected]. Before you consider Celldex Therapeutics, you'll want to hear this. MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Celldex Therapeutics wasn't on the list. While Celldex Therapeutics currently has a Moderate Buy rating among analysts, top-rated analysts believe these five stocks are better buys. With the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow. Continue following MarketBeat

GlobeNewswire
Sep 8th, 2026
Celldex to present at upcoming Investor Conference.

Celldex to present at upcoming Investor Conference. HAMPTON, N.J., Sept. 08, 2026 (GLOBE NEWSWIRE) - Celldex (NASDAQ:CLDX) announced today that management will participate in a fireside chat at the upcoming Cantor Global Healthcare Conference on September 10, 2026 at 8:00am ET. The webcast of the presentation will be available on the "Events and Presentations" page of the "Investors" section of the Celldex Website. Replays will be available for 90 days following the event. About Celldex Celldex is pioneering new horizons in immunology to deliver life-changing therapies. We are relentless in our pursuit of novel antibody-based treatments that engage the human immune system and directly affect critical pathways to improve the lives of patients with allergic, inflammatory and autoimmune disorders. Visit www.celldex.com. Company Contacts Sarah Cavanaugh Senior Vice President, Corporate Affairs & Administration (508) 864-8337 [email protected] Elizabeth Higgins Executive Director, Investor Relations & Corporate Communications (857) 404-2088 [email protected]

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