Cradle

Cradle

Machine learning for protein design and optimization

About Cradle

Simplify's Rating
Why Cradle is rated
A
Rated A on Competitive Edge
Rated A on Growth Potential
Rated A on Differentiation

Industries

AI & Machine Learning

Biotechnology

Company Size

51-200

Company Stage

Series B

Total Funding

$103.1M

Headquarters

Amsterdam, Netherlands

Founded

2021

Overview

Company Does Not Provide H1B Sponsorship

Cradle.bio designs proteins using machine learning, which simplifies a traditionally complex process. The company generates protein sequences with predicted performance scores, allowing clients to bring their products to market more quickly while retaining ownership of their intellectual property. Cradle.bio stands out by optimizing multiple properties and tasks simultaneously, making it more efficient than traditional methods. The goal is to help clients achieve their objectives in half the time, positioning Cradle.bio as a valuable partner in the bioinformatics market.

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Simplify's Take

What believers are saying

  • Cradle.bio's platform accelerates R&D projects by 1.2 to 12 times.
  • The company recently raised $73M in Series B funding, boosting its growth potential.
  • Cradle.bio's secure platform is highly valued for privacy and data protection.

What critics are saying

  • Increased competition from AI-driven drug discovery companies like Anima Biotech and Atomwise.
  • The Netherlands' biotech ambitions could pressure Cradle to innovate continuously.
  • Regulatory changes from the EU AI Champions Initiative may impact Cradle's operations.

What makes Cradle unique

  • Cradle.bio uses machine learning to design proteins, reducing time-to-market for clients.
  • The platform ensures clients retain full ownership of their intellectual property.
  • Cradle.bio optimizes multiple properties in a single round, unlike traditional methods.

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Funding

Total Funding

$103M

Above

Industry Average

Funded Over

3 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidly—often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$65M
Substack
$73M
Cradle
$100M
ClickUp

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Life Insurance

Disability Insurance

Company Equity

Professional Development Budget

Remote Work Options

Growth & Insights and Company News

Headcount

6 month growth

2%

1 year growth

-4%

2 year growth

11%
Labiotech
May 9th, 2025
The Netherlands’ Biotech Scene: The Country Sets Its Sights On Becoming A Global Leader By 2040

Newsletter Signup - Under Article / In Page"*" indicates required fields With one of the most densely concentrated life sciences and biotech ecosystems in Europe, the Netherlands is home to numerous biotech and pharmaceutical companies, and also happens to be the headquarters of the European Medicines Agency (EMA), which is now based in Amsterdam after it had to move out of London when the U.K. voted to leave the European Union (EU). As the Netherlands now sets its sights on becoming a global biotech leader by 2040, we take a deeper look at the country’s biotech scene.The Netherlands: Already a well-established biotech hubOverall, the biotech sector in the Netherlands is internationally oriented, with a strong base in early-stage research, academic excellence, and public-private partnerships.According to Annemiek Verkamman, managing director of hollandbio, a biotech industry association, the Netherlands has been building its biotech sector for decades, meaning that it is now a well-established life sciences and biotech hub. “We have world-renowned crop breeding companies, Leiden and Oss are leading biopharmaceutical hub spots, and there is a historical presence of industrial biotech knowledge institutions and companies such as DSM-Firmenich and Corbion.”Thanks to this, the country is now considered to be one of the leading European biotech hubs, along with the likes of Switzerland, France, and the U.K. It is currently home to around 1,979 life sciences companies, including several well-known biotech companies, such as Amsterdam-based uniQure, which developed the first approved gene therapy for hemophilia B.Furthermore, over the past couple of years – particularly since the arrival of the EMA in Amsterdam – the Netherlands has managed to attract a significant number of foreign life sciences companies, whether that be big pharma companies or up-and-coming biotechs. In fact, several large drugmakers, including AstraZeneca, Novartis, and Roche, currently have bases in the country

Labiotech
Mar 27th, 2025
12 Ai Drug Discovery Companies You Should Know About

Newsletter Signup - Under Article / In Page"*" indicates required fields Artificial intelligence (AI) has taken the biotech industry by storm, allowing companies to speed up the drug discovery process while also making it more cost-effective. With so many companies in the industry now embracing the technology, we take a look at 12 AI drug discovery companies. The COVID-19 pandemic revealed AI to be an essential tool in helping to find treatments and vaccines with greater speed and precision. Since then, there have been several drug discovery breakthroughs for AI within the biopharma industry, from helping to quickly and efficiently discover a new antibiotic called abaucin to combat a multi-drug resistant bacteria, to fully discovering and designing a drug that has entered clinical trials. Here are 12 AI drug discovery companies currently making great strides with their technology. Anima Biotech Technology: mRNA biology modulators Disease areas: Immunology, oncology and neuroscienceRecent news: Announced promising preclinical data for lead pulmonary fibrosis candidate Anima Biotech’s AI drug discovery technology is built around its mRNA Lightning.AI platform, which images hundreds of cellular pathways in both healthy and diseased cells to train disease-specific AI models, making use of neural networks to help these models distinguish between healthy and diseased cells and identify dysregulated pathways. These pathways are subsequently analyzed to uncover novel targets backed by experimental validation. Anima currently has 20 preclinical candidates being evaluated for immunology, oncology, and neuroscience indications, with its most advanced candidate indicated for the treatment of lung fibrosis. The company announced in February 2024 that this candidate had shown promising preclinical results and could open up new avenues for treating patients with idiopathic pulmonary fibrosis. The AI drug discovery company also has ongoing collaborations with several pharma giants. After initially partnering with Eli Lilly in 2018 and Takeda in 2021, its most recent partnership was formed with AbbVie in 2023 for the discovery and development of mRNA biology modulators against oncology and immunology targets. Atomwise Technology: TYK2 inhibitor  Disease area: Autoimmune and autoinflammatory diseasesRecent news: Published results showcasing AtomNet’s ability for drug discoveryAtomwise is leveraging the power of AI in an attempt to revolutionize small molecule drug discovery

Startupticker
Feb 13th, 2025
Swiss Startups And Scale-Upd Join The Eu Ai Champions Initiative

Business and politics must align to drive innovation, particularly in today's technological era where artificial intelligence (AI) is increasingly dominant. The newly launched €150 billion EU AI Champions Initiative marks a significant step forward, with 60 European companies - both startups and Incumbents uniting to streamline AI regulations. Switzerland has a strong representation with four startups and scale-ups supporting the vision of transforming industries with AIThe EU AI Champions Initiative launched at the AI Action Summit in Paris, hosted by French President Emmanuel Macron, aims to position Europe as a global leader in Artificial Intelligence (AI). The initiative will foster collaboration across technology, industry, and policy sectors, boosting AI adoption, talent, investments and innovation to drive Europe’s economic growth and global competitiveness.For the first time, European leaders from across countries, industries, technology, and policy have come together to create a functional flywheel aimed at accelerating Europe's leadership in artificial intelligence. By framing an ambitious and positive vision for Europe, mobilizing talent and capital, and driving AI adoption, this unprecedented collaboration seeks to create self-reinforcing mechanisms that will foster the growth of new technology companies and strengthen the global leadership of Europe’s established industries. Together, they aim to drive economic growth and social prosperity across the continent.The initiative emphasizes the need for a regulatory environment that supports AI innovation while ensuring ethical and secure use of AI technologies

AgFunder News
Dec 27th, 2024
Eggs, Coffee, Chocolate, And The Culture Wars: Foodtech In 2024

“A lot of foodtech founders in this dry capital environment are beating their heads against the wall with the conviction that the wall will break before their heads do,” observes Paul Shapiro at The Better Meat Co. “That said, deals are still getting done, and important technology is still being developed.”. In some cases, startups have found themselves swimming against the tide, with alt meat getting caught up in the culture wars (spoiler alert: JD Vance does not approve of “disgusting fake meat” and Ron DeSantis has been “fighting back against the global elite’s plan to force the world to eat meat grown in a petri dish”) while the leading player in livestock methane reduction has been battling a barrage of misinformation on social media. In other cases, a confluence of factors has created far more favorable conditions for foodtech startups, however

Dutch IT Leaders
Nov 26th, 2024
Cradle secures major investment for AI protein engineering

Cradle, an AI protein-engineering specialist, has received a significant investment. The company uses AI to design proteins, aiming to improve human and planetary health by developing new medicines, sustainable materials, and more. Cradle's platform accelerates R&D projects by 1.2 to 12 times and reduces costs by up to 90%. Since commercialization, it has gained over 21 clients and is developing 31 proteins.

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