Generate Biomedicines

Generate Biomedicines

Develops on-demand medicines using generative biology

Overview

Generate Biomedicines uses generative biology to design medicines with its Generate Platform, combining machine learning, biological engineering, and medicine. The platform analyzes millions of proteins to learn how natural function is encoded and then designs and produces medicines with specific therapeutic functions, enabling on-demand protein and drug design across multiple therapeutic areas. It differentiates itself by blending a scalable, data-driven design process with hands-on biology to move drug discovery from purely exploratory work to proactive on-demand creation, with a goal of democratizing biotherapeutics. The company's aim is to make medicines faster, more accessible, and available across diverse therapeutic areas.

About Generate Biomedicines

Simplify's Rating
Why Generate Biomedicines is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

Data & Analytics

AI & Machine Learning

Biotechnology

Healthcare

Company Size

201-500

Company Stage

IPO

Headquarters

Somerville, Massachusetts

Founded

2018

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Simplify's Take

What believers are saying

  • Generate ended Q2 2026 with $457.4 million cash, funding operations into 2028.
  • 2026 catalysts include GB-0895 asthma readouts, GB-4362 dosing, and GB-5267 initiation.
  • Nvidia bought 833,325 shares in 2026, validating Generate's compute-intensive platform.

What critics are saying

  • Revenue fell to $6.3 million in Q2 2026, while losses kept widening.
  • Novartis and Amgen fund all revenue; remaining payments run through 2026-2027.
  • GB-0895 Phase 3 failure or GB-4362/GB-5267 delays crush the valuation.

What makes Generate Biomedicines unique

  • Generate Biomedicines programs proteins with machine-learning generative biology, not screening.
  • Novartis advanced a Generate-designed biologic into preclinical development in 2026.
  • GB-0895 reached Phase 3 in severe asthma before commercial launch.

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Funding

Total Funding

$1.1B

Above

Industry Average

Funded Over

4 Rounds

IPO funding comparison data is currently unavailable. We're working to provide this information soon!
IPO Funding Comparison
Coming Soon

Benefits

Flexible Work Hours

Growth & Insights and Company News

Headcount

6 month growth

0%

1 year growth

-1%

2 year growth

0%
Crypto Briefing
Jun 27th, 2026
Nvidia backs Generate Biomedicines with $10.4M stake in AI drug discovery targeting $1.8T market

Nvidia's venture arm has disclosed ownership of 833,325 shares in Generate:Biomedicines, valued at approximately $10.4 million, according to the company's latest 13F filing. Generate, which trades on Nasdaq under ticker GENB, uses generative AI to design therapeutic proteins and drug candidates from scratch. The biotech startup has a Phase 3 clinical trial underway for severe asthma and multiple oncology candidates with FDA Fast Track designation. Generate raised $700 million in total funding, including a $273 million Series C round in September 2023 that included NVentures and Amgen, before going public in February 2026. The investment positions Nvidia in the drug discovery sector, where protein simulation and molecular interaction prediction require substantial computational power, creating long-term demand for its chips.

Noah Business Intelligence
May 31st, 2026
HarbourVest takes $21M stake in Generate Biomedicines as ML drug platform advances to clinic

HarbourVest Partners has taken a significant stake in Generate Biomedicines, purchasing 1,722,210 shares valued at approximately $21.03 million in the first quarter, according to an SEC filing. The position represented 21% of HarbourVest's reportable 13F assets by 31 March. The Somerville, Massachusetts-based biotech uses machine learning to design protein drugs. Its lead programme, GB-0895, is in late-stage testing for severe asthma, whilst oncology assets GB-4362 and GB-5267 are advancing through clinical development. Generate ended the first quarter with $516.6 million in cash following a $369.3 million March listing, providing a runway into early 2028. However, revenue fell to $7.2 million from $8.8 million year-on-year, whilst net losses widened to $61.7 million. Shares closed at $13.12 on Friday, 12.5% below the $16 IPO price.

Farmers Cooperative Elevator Assn.
May 20th, 2026
Nvidia invests $10.4M in AI biotech Generate Biomedicines advancing Phase 3 asthma trials

Nvidia has invested $10.4 million in Generate Biomedicines, acquiring 833,325 shares of the AI biotech company, according to its latest 13F filing. The investment comes as Generate Biomedicines advances multiple programmes into clinical development, including a Phase 3 asthma treatment and several oncology therapies. Generate Biomedicines uses AI and machine learning to design new proteins and potential medicines, accelerating traditional drug development processes. The company recently went public in February 2026 and ended its first quarter with $516.6 million in cash, sufficient to fund operations until 2028. The clinical-stage biotech currently has no approved products but generated $7.2 million in revenue from research collaborations with Amgen and Novartis. Wall Street analysts give the stock a "Strong Buy" rating, with a mean price target of $25.40, suggesting 96% upside potential.

Yahoo Finance
May 20th, 2026
This AI Biotech Stock Landed a $10.4 Million Nvidia Investment

Nvidia’s backing highlights growing confidence in AI-powered biotech stocks.

PR Newswire
May 7th, 2026
Generate Biomedicines reports Q1 2026 results with $516.6M cash post-IPO, advances three clinical trials

Generate Biomedicines has reported first quarter 2026 financial results, with cash, cash equivalents and marketable securities totalling $516.6 million as of 31 March 2026, up from $221.5 million at year-end 2025, following $369.3 million in net proceeds from its IPO completed in March. The clinical-stage biotech is advancing multiple programmes. Phase 3 trials for GB-0895, an anti-TSLP treatment for severe asthma, continue alongside a Phase 1b trial in COPD. Its GB-4362 MMAE neutraliser has activated clinical trial sites, with first patient dosing expected mid-2026, whilst GB-5267, a MUC16 CAR T therapy developed with Roswell Park, is expected to begin dosing in the second half of 2026. Net loss for the quarter was $61.7 million, compared with $44.3 million in the same period last year.

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