CCresilon makes medical devices that stop bleeding with a plant-based adhesive gel. Its main product, VETIGEL, is a fast-acting gel designed to control bleeding in veterinary patients, and Cresilon serves human trauma and surgical markets as well. The gel is applied to a wound and works to seal and promote clotting within seconds without needing manual pressure. Cresilon differentiates itself by offering a gel-based hemostat and by being among the first to target veterinary applications with a rapid, easy-to-use solution, along with direct sales and partnerships (for example, the VerticalVet Preferred Partnership) to reach clinics and hospitals. The company’s goal is to broaden the gel technology’s uses to improve wound care and save lives across veterinary, human trauma, and surgical settings.
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Industries
Company Size
51-200
Company Stage
Early VC
Total Funding
$116.5M
Headquarters
New York City, New York
Founded
2010
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Total Funding
$116.5M
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Funded Over
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Cresilon, a Brooklyn-based biotechnology company, has won a Phase I Small Business Innovation Research (SBIR) contract from AFWERX, the US Air Force's innovation arm. The contract covers TRAUMAGEL, the company's hemostatic product for stopping severe bleeding. The work will test the plant-based hydrogel in settings where military personnel cannot quickly reach medical support. Cresilon will start on June 22, 2026. "Uncontrolled hemorrhage remains the leading cause of preventable death on the battlefield," said Joe Landolina, co-founder and chief executive officer. He said current hemostatic solutions can be hard to use in demanding conditions. The Department of the Air Force began its Open Topic SBIR/STTR program in 2018. No contract value was disclosed.
U.S. Air Force selects Cresilon's TRAUMAGEL through AFWERX SBIR program to advance hemorrhage control for military use. Phase I contract supports the development of TRAUMAGEL for military personnel operating without immediate access to medical support NEW YORK, Oct. 26, 2026 /PRNewswire/ - Cresilon Inc. ("Cresilon"), a Brooklyn-based biotechnology company focused on hemostatic medical device technologies, announces it has been selected by AFWERX for a Phase I Small Business Innovation Research (SBIR) contract focused on TRAUMAGEL(R) to address the most pressing challenges in the Department of the Air Force (DAF). The Air Force Research Laboratory and AFWERX have partnered to streamline the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) process by accelerating the small business experience through faster proposal to award timelines, changing the pool of potential applicants by expanding opportunities to small business and eliminating bureaucratic overhead by continually implementing process improvement changes in contract execution. The DAF began offering the Open Topic SBIR/STTR program in 2018 which expanded the range of innovations the DAF funded and now on June 22nd 2026, Cresilon will start its journey to create and provide innovative capabilities that will strengthen the national defense of the United States of America. "Uncontrolled hemorrhage remains the leading cause of preventable death on the battlefield, and current hemostatic solutions can be difficult to use in the most demanding operational settings," said Joe Landolina, co-founder and CEO of Cresilon. "Selection through AFWERX recognizes TRAUMAGEL's potential to address some of the most challenging hemorrhage control scenarios faced by military personnel. This contract will help evaluate the technology in settings where immediate medical support may not be available." The views expressed are those of the author and do not necessarily reflect the official policy or position of the Department of the Air Force, the Department of War, or the U.S. government. About Cresilon Cresilon(R) is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company's proprietary hydrogel technology. The company's plant-based technology has revolutionized the current standard by stopping bleeding in seconds. The company's current and future product lines target trauma care, biosurgery, and animal health. Cresilon's mission is to save lives. The company was recognized by Fast Company as one of the World's 50 Most Innovative Companies and named an EMS World Innovation Awards winner for TRAUMAGEL. For more information about Cresilon, visit www.cresilon.com. About AFRL The Air Force Research Laboratory is the Department of the Air Force's primary scientific research and development center and one of six centers within Air Force Materiel Command. AFRL leads the discovery, development and delivery of technologies for air, space and the multidomain. With a workforce spanning seven mission areas at more than 40 locations worldwide, AFRL conducts research ranging from basic science to advanced technology development. For more information, visit afresearchlab.com. About AFWERX AFWERX, the innovation arm of the Department of the Air Force and a division within the Air Force Research Laboratory, partners with small businesses, startups and nontraditional vendors to address challenges facing Airmen and Guardians. Headquartered at Wright-Patterson Air Force Base, Ohio, AFWERX strengthens the defense industrial base by expanding access to innovators, building partnerships and accelerating the transition of critical technologies to operational capability. In fiscal year 2025, AFWERX awarded more than 1,000 contracts totaling $1.37 billion and achieved 438 Phase III transitions valued at $8.1 billion. For more information, visit afwerx.com. SOURCE Cresilon
Brooklyn-based biotechnology company Cresilon has launched a next-generation version of its TRAUMAGEL hemostatic gel, debuting at EMS World Expo 2026 in Orlando, Florida. The new compact syringe format enables one-handed application whilst maintaining the same bleeding control technology as the original product. TRAUMAGEL is a plant-based gel that controls moderate to severe bleeding in seconds, requiring no preparation before use. The redesigned format offers a smaller footprint for tactical, prehospital and hospital settings, whilst the original version remains available. "When a trauma patient is severely bleeding, every second matters," said Joe Landolina, CEO and co-founder of Cresilon. Published clinical evidence documents successful hemorrhage control in complex traumatic injuries, with providers reporting faster application and quicker bleeding control.
Cresilon named one of the World's 50 Most Innovative Companies by Fast Company. * 6 hrs ago PR Newswire NEW YORK, March 25, 2026 Ranked No. 1 in the medical devices category and No. 46 on Fast Company's World's 50 Most Innovative Companies list NEW YORK, March 25, 2026 /PRNewswire/ - Cresilon has been named to Fast Company's World's 50 Most Innovative Companies of 2026. The company ranked No. 1 in the medical devices category and No. 46 overall. This marks the second time Cresilon has earned the top spot in its category, after first being recognized in 2024. "Being named one of the World's 50 Most Innovative Companies and ranked No. 1 in medical devices again speaks to the work our team is doing every day," said Joe Landolina, co-founder and CEO of Cresilon. "We started Cresilon with a clear mission to save lives. Today, TRAUMAGEL is in the hands of first responders and trauma care providers across the country and making a real impact. This recognition reflects the progress we've made and the real-world impact our solution is having in trauma care." Since its last recognition, Cresilon has advanced its hemostatic technology and expanded its reach. TRAUMAGEL(R) received FDA clearance in August 2024 and launched nationwide in January 2025. Clinical use cases reported by critical care providers show TRAUMAGEL saved at least one life per day on average in 2025. The product is now used by first responders and hospitals across the U.S. to control bleeding quickly and help prevent death from severe blood loss, which accounts for more than 35% of prehospital deaths. By the end of 2025, TRAUMAGEL was in use across all targeted care settings, including law enforcement, fire, EMS, and hospital trauma teams. The product is also being evaluated by the U.S. military and has been fielded by select units. To support this growth, Cresilon expanded its manufacturing footprint to 55,000 square feet at its state-of-the-art biomanufacturing facility in Brooklyn. The World's Most Innovative Companies is Fast Company's hallmark franchise and one of its most anticipated editorial efforts of the year. This year's list highlights businesses shaping industry and culture through innovation. Alongside the World's 50 Most Innovative Companies, Fast Company also recognized 720 organizations across 59 sectors and regions. To determine honorees, Fast Company's editors and writers review companies driving progress across industries and regions. They evaluate thousands of submissions through a competitive process. The result is a global look at innovation, from early-stage startups to some of the most valuable companies in the world. "Our list of the Most Innovative Companies is about spotlighting organizations that don't just adapt to change. They drive it," said Brendan Vaughan, editor-in-chief of Fast Company. "The companies we honor this year are setting the pace for their industries and showing what sustained innovation can achieve." The full list of Fast Company's Most Innovative Companies honorees is available at fastcompany.com. It will also appear on newsstands beginning March 31, 2026. About Cresilon Cresilon(R) is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices using its proprietary hydrogel technology. The company's plant-based technology stops bleeding in seconds. Its current and future product lines target trauma care, biosurgery, and animal health. Cresilon's mission is to save lives. The company has been recognized by Fast Company as one of the World's 50 Most Innovative Companies and named an EMS World Innovation Awards winner for TRAUMAGEL. For more information, visit www.cresilon.com. SOURCE Cresilon
Cresilon raised $17 million in a late stage venture capital round following growth in both the company's footprint and distribution network in recent months.
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Industries
Company Size
51-200
Company Stage
Early VC
Total Funding
$116.5M
Headquarters
New York City, New York
Founded
2010
Find jobs on Simplify and start your career today
Don't see your dream role? Check out thousands of other roles on Simplify.Browse all jobs