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Cresilon

Plant-based hemostatic gel for bleeding control

Overview

Cresilon makes medical devices that stop bleeding with a plant-based adhesive gel. Its main product, VETIGEL, is a fast-acting gel designed to control bleeding in veterinary patients, and Cresilon serves human trauma and surgical markets as well. The gel is applied to a wound and works to seal and promote clotting within seconds without needing manual pressure. Cresilon differentiates itself by offering a gel-based hemostat and by being among the first to target veterinary applications with a rapid, easy-to-use solution, along with direct sales and partnerships (for example, the VerticalVet Preferred Partnership) to reach clinics and hospitals. The company’s goal is to broaden the gel technology’s uses to improve wound care and save lives across veterinary, human trauma, and surgical settings.

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About Cresilon

Simplify's Rating
Why Cresilon is rated
B-
Rated B on Competitive Edge
Rated B on Growth Potential
Rated C on Differentiation

Industries

BiotechnologyHealthcare

Company Size

51-200

Company Stage

Early VC

Total Funding

$116.5M

Headquarters

New York City, New York

Founded

2010

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What believers are saying

  • Sept. 30, 2026 TRAUMAGEL Next Generation expanded use across EMS, tactical, and hospitals.
  • Aug. 4, 2025 Vizient gave TRAUMAGEL an Innovative Technology contract nationwide.
  • June 16, 2025 McCarthy Vet opened VETIGEL sales across Canada.

What critics are saying

  • Cresilon still depends on expensive clinician training to displace gauze, clamps, and legacy hemostats.
  • In 2025, Cresilon pulled a launch after field misses, proving execution risk.
  • TRAUMAGEL remains the revenue engine; procurement stalls threaten Cresilon's runway and valuation.

What makes Cresilon unique

  • Cresilon's plant-based hydrogel stops bleeding in seconds without manual pressure or preparation.
  • TRAUMAGEL's 2026 compact syringe enables one-handed EMS use and go-bag portability.
  • VETIGEL reached 60,000 procedures worldwide and VerticalVet opened access to 1,800 members.

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Funding

Total Funding

$116.5M

Above

Industry Average

Funded Over

6 Rounds

Notable Investors:
Early VC funding comparison data is currently unavailable. We're working to provide this information soon!
Early VC Funding Comparison Coming Soon

Benefits

  • Paid Vacation
  • Paid Sick Leave
  • Paid Holidays
  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Health Savings Account/Flexible Spending Account
  • Disability Insurance
  • Life Insurance
  • Commuter Benefits
  • 401(k) Company Match
  • Hybrid Work Options

Growth & Insights and Company News

6 month growth

-1%

1 year growth

1%

2 year growth

0%
Yahoo Finance
Oct 26th, 2026
US Air Force picks Cresilon's TRAUMAGEL for hemorrhage control in Phase I SBIR contract

Cresilon, a Brooklyn-based biotechnology company, has won a Phase I Small Business Innovation Research (SBIR) contract from AFWERX, the US Air Force's innovation arm. The contract covers TRAUMAGEL, the company's hemostatic product for stopping severe bleeding. The work will test the plant-based hydrogel in settings where military personnel cannot quickly reach medical support. Cresilon will start on June 22, 2026. "Uncontrolled hemorrhage remains the leading cause of preventable death on the battlefield," said Joe Landolina, co-founder and chief executive officer. He said current hemostatic solutions can be hard to use in demanding conditions. The Department of the Air Force began its Open Topic SBIR/STTR program in 2018. No contract value was disclosed.

Health Technology Net
Oct 26th, 2026
U.S. Air Force selects Cresilon's TRAUMAGEL through AFWERX SBIR program to advance hemorrhage control for military use.

U.S. Air Force selects Cresilon's TRAUMAGEL through AFWERX SBIR program to advance hemorrhage control for military use. Phase I contract supports the development of TRAUMAGEL for military personnel operating without immediate access to medical support NEW YORK, Oct. 26, 2026 /PRNewswire/ - Cresilon Inc. ("Cresilon"), a Brooklyn-based biotechnology company focused on hemostatic medical device technologies, announces it has been selected by AFWERX for a Phase I Small Business Innovation Research (SBIR) contract focused on TRAUMAGEL(R) to address the most pressing challenges in the Department of the Air Force (DAF). The Air Force Research Laboratory and AFWERX have partnered to streamline the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) process by accelerating the small business experience through faster proposal to award timelines, changing the pool of potential applicants by expanding opportunities to small business and eliminating bureaucratic overhead by continually implementing process improvement changes in contract execution. The DAF began offering the Open Topic SBIR/STTR program in 2018 which expanded the range of innovations the DAF funded and now on June 22nd 2026, Cresilon will start its journey to create and provide innovative capabilities that will strengthen the national defense of the United States of America. "Uncontrolled hemorrhage remains the leading cause of preventable death on the battlefield, and current hemostatic solutions can be difficult to use in the most demanding operational settings," said Joe Landolina, co-founder and CEO of Cresilon. "Selection through AFWERX recognizes TRAUMAGEL's potential to address some of the most challenging hemorrhage control scenarios faced by military personnel. This contract will help evaluate the technology in settings where immediate medical support may not be available." The views expressed are those of the author and do not necessarily reflect the official policy or position of the Department of the Air Force, the Department of War, or the U.S. government. About Cresilon Cresilon(R) is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company's proprietary hydrogel technology. The company's plant-based technology has revolutionized the current standard by stopping bleeding in seconds. The company's current and future product lines target trauma care, biosurgery, and animal health. Cresilon's mission is to save lives. The company was recognized by Fast Company as one of the World's 50 Most Innovative Companies and named an EMS World Innovation Awards winner for TRAUMAGEL. For more information about Cresilon, visit www.cresilon.com. About AFRL The Air Force Research Laboratory is the Department of the Air Force's primary scientific research and development center and one of six centers within Air Force Materiel Command. AFRL leads the discovery, development and delivery of technologies for air, space and the multidomain. With a workforce spanning seven mission areas at more than 40 locations worldwide, AFRL conducts research ranging from basic science to advanced technology development. For more information, visit afresearchlab.com. About AFWERX AFWERX, the innovation arm of the Department of the Air Force and a division within the Air Force Research Laboratory, partners with small businesses, startups and nontraditional vendors to address challenges facing Airmen and Guardians. Headquartered at Wright-Patterson Air Force Base, Ohio, AFWERX strengthens the defense industrial base by expanding access to innovators, building partnerships and accelerating the transition of critical technologies to operational capability. In fiscal year 2025, AFWERX awarded more than 1,000 contracts totaling $1.37 billion and achieved 438 Phase III transitions valued at $8.1 billion. For more information, visit afwerx.com. SOURCE Cresilon

PR Newswire
Sep 30th, 2026
Cresilon launches compact TRAUMAGEL next-gen hemostatic gel for first responders

Brooklyn-based biotechnology company Cresilon has launched a next-generation version of its TRAUMAGEL hemostatic gel, debuting at EMS World Expo 2026 in Orlando, Florida. The new compact syringe format enables one-handed application whilst maintaining the same bleeding control technology as the original product. TRAUMAGEL is a plant-based gel that controls moderate to severe bleeding in seconds, requiring no preparation before use. The redesigned format offers a smaller footprint for tactical, prehospital and hospital settings, whilst the original version remains available. "When a trauma patient is severely bleeding, every second matters," said Joe Landolina, CEO and co-founder of Cresilon. Published clinical evidence documents successful hemorrhage control in complex traumatic injuries, with providers reporting faster application and quicker bleeding control.

The Mirror Democrat and Savanna Times-Journal
Mar 25th, 2026
Cresilon named one of the World's 50 Most Innovative Companies by Fast Company.

Cresilon named one of the World's 50 Most Innovative Companies by Fast Company. * 6 hrs ago PR Newswire NEW YORK, March 25, 2026 Ranked No. 1 in the medical devices category and No. 46 on Fast Company's World's 50 Most Innovative Companies list NEW YORK, March 25, 2026 /PRNewswire/ - Cresilon has been named to Fast Company's World's 50 Most Innovative Companies of 2026. The company ranked No. 1 in the medical devices category and No. 46 overall. This marks the second time Cresilon has earned the top spot in its category, after first being recognized in 2024. "Being named one of the World's 50 Most Innovative Companies and ranked No. 1 in medical devices again speaks to the work our team is doing every day," said Joe Landolina, co-founder and CEO of Cresilon. "We started Cresilon with a clear mission to save lives. Today, TRAUMAGEL is in the hands of first responders and trauma care providers across the country and making a real impact. This recognition reflects the progress we've made and the real-world impact our solution is having in trauma care." Since its last recognition, Cresilon has advanced its hemostatic technology and expanded its reach. TRAUMAGEL(R) received FDA clearance in August 2024 and launched nationwide in January 2025. Clinical use cases reported by critical care providers show TRAUMAGEL saved at least one life per day on average in 2025. The product is now used by first responders and hospitals across the U.S. to control bleeding quickly and help prevent death from severe blood loss, which accounts for more than 35% of prehospital deaths. By the end of 2025, TRAUMAGEL was in use across all targeted care settings, including law enforcement, fire, EMS, and hospital trauma teams. The product is also being evaluated by the U.S. military and has been fielded by select units. To support this growth, Cresilon expanded its manufacturing footprint to 55,000 square feet at its state-of-the-art biomanufacturing facility in Brooklyn. The World's Most Innovative Companies is Fast Company's hallmark franchise and one of its most anticipated editorial efforts of the year. This year's list highlights businesses shaping industry and culture through innovation. Alongside the World's 50 Most Innovative Companies, Fast Company also recognized 720 organizations across 59 sectors and regions. To determine honorees, Fast Company's editors and writers review companies driving progress across industries and regions. They evaluate thousands of submissions through a competitive process. The result is a global look at innovation, from early-stage startups to some of the most valuable companies in the world. "Our list of the Most Innovative Companies is about spotlighting organizations that don't just adapt to change. They drive it," said Brendan Vaughan, editor-in-chief of Fast Company. "The companies we honor this year are setting the pace for their industries and showing what sustained innovation can achieve." The full list of Fast Company's Most Innovative Companies honorees is available at fastcompany.com. It will also appear on newsstands beginning March 31, 2026. About Cresilon Cresilon(R) is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices using its proprietary hydrogel technology. The company's plant-based technology stops bleeding in seconds. Its current and future product lines target trauma care, biosurgery, and animal health. Cresilon's mission is to save lives. The company has been recognized by Fast Company as one of the World's 50 Most Innovative Companies and named an EMS World Innovation Awards winner for TRAUMAGEL. For more information, visit www.cresilon.com. SOURCE Cresilon

Industry City
Sep 10th, 2025
Park Slope biotech firm raises $17M after recent growth spurt

Cresilon raised $17 million in a late stage venture capital round following growth in both the company's footprint and distribution network in recent months.

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