Delfi Diagnostics

Delfi Diagnostics

Advanced cancer detection using cell-free DNA

About Delfi Diagnostics

Simplify's Rating
Why Delfi Diagnostics is rated
A-
Rated B on Competitive Edge
Rated A on Growth Potential
Rated A on Differentiation

Industries

AI & Machine Learning

Healthcare

Company Size

51-200

Company Stage

Series B

Total Funding

$330.5M

Headquarters

Baltimore, Maryland

Founded

2019

Overview

Delfi Diagnostics focuses on early cancer detection using advanced machine learning and fragmentomics, which involves analyzing fragments of cell-free DNA. Their technology differs from traditional methods by scanning millions of data points to find previously unrecognized cancer-associated fragments, allowing for a more comprehensive detection of cancer. The team consists of experts in cancer biology, bioinformatics, and machine learning, led by Dr. Victor Velculescu, a recognized figure in genomics and cancer research. Delfi's business model includes offering their cancer detection services to healthcare providers and patients, aiming to improve the efficiency and effectiveness of cancer screening.

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Simplify's Take

What believers are saying

  • Recent AI advancements enhance the sensitivity of Delfi's fragmentomics-based cancer detection.
  • Partnerships with biotech firms expand Delfi's technology applications and market reach.
  • Merck's investment accelerates Delfi's genomic technology development and R&D capabilities.

What critics are saying

  • Competition from City of Hope's blood test may capture Delfi's market share.
  • Over-reliance on partnerships could pose risks if collaborations don't yield expected results.
  • New executive appointments may lead to strategic shifts or internal disruptions.

What makes Delfi Diagnostics unique

  • Delfi Diagnostics uses fragmentomics for early cancer detection, unlike traditional mutation-focused methods.
  • The company integrates AI with genome-wide fragmentomics for high sensitivity in cancer screening.
  • Delfi's team includes experts in genomics, bioinformatics, and regulated software development.

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Funding

Total Funding

$330.5M

Above

Industry Average

Funded Over

3 Rounds

Series B funding is typically for startups that have proven their business model and need more funding to expand rapidlyโ€”often by entering new markets or adding more products. Investors are usually venture capital firms that specialize in later-stage investments.
Series B Funding Comparison
Above Average

Industry standards

$35M
$45M
Linktree
$65M
Substack
$100M
ClickUp
$225M
Delfi Diagnostics

Benefits

Health Insurance

Dental Insurance

Vision Insurance

Parental Leave

Flexible Time Off

Paid Holidays

Growth & Insights and Company News

Headcount

6 month growth

โ†‘ 2%

1 year growth

โ†‘ 0%

2 year growth

โ†‘ 4%
PR Newswire
Apr 25th, 2025
Delfi Diagnostics To Present Early Detection And Advanced Cancer Monitoring Technology Updates At Aacr Annual Meeting

Fragmentomics pioneer showcases DELFI-TF treatment monitoring solution alongside early detection capabilities at a premier oncology research eventBALTIMORE and PALO ALTO, Calif., April 25, 2025 /PRNewswire/ -- DELFI Diagnostics, Inc ., developer of innovative blood-based tests that leverage cell-free DNA (cfDNA) fragmentomics for cancer detection and monitoring, today announced its team is presenting at the upcoming 2025 American Association for Cancer Research (AACR) Annual Meeting in Chicago, IL. DELFI is showcasing its groundbreaking DELFI-TF technology for treatment response monitoring alongside its early detection capabilities."Our presentations at AACR highlight how DELFI's fragmentomics platform is transforming both early cancer detection and treatment monitoring," said Victor E. Velculescu, MD, PhD, DELFI Diagnostics Founder and Board Director. "The DELFI technology represents a paradigm shift in how we detect cancer by combining genome-wide fragmentomics of DNA in the blood with AI algorithms for high sensitivity in the screening setting as well as for noninvasively measuring treatment efficacy in advanced cancer patients. "DELFI is presenting multiple podium and poster sessions at AACR, including:Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection presented by Victor E. Velculescu, MD, PhDTuesday, April 29 , 11:06 AM - 11:26 AM CT, Room S100 BC (Grand Ballroom BC) - McCormick Place SouthLeveraging the cfDNA fragmentome to predict immunotherapy response presented by Valsamo Anagnostou, MD, PhDMonday, April 28 , 3:05 PM - 3:20 PM CT, Room S105 - McCormick Place SouthAnalysis of lung cancer clinical characteristics using cell-free DNA fragmentomes presented by Lorenzo Rinaldi, PhDMonday, April 28 , 9:00 AM - 12:00 PM CT, Section 28, Poster 29Cell-free DNA fragmentomes for treatment response monitoring in patients with metastatic colorectal cancer: the DOLPHIN study presented by Denise E

Bizjournals
Oct 30th, 2024
8 things to know: New Under Armour HQ almost complete

Canton-based Delfi Diagnostics has named Robert Guigley as its new chief commercial officer.

PR Newswire
Oct 28th, 2024
DELFI Diagnostics Working with Incendia Therapeutics to Employ Advanced Treatment Monitoring Test in a Phase 1 Clinical Trial

DELFI Diagnostics working with Incendia Therapeutics to employ advanced treatment monitoring test in a Phase 1 clinical trial.

PR Newswire
Aug 26th, 2024
DELFI Diagnostics Appoints Thomas Russo as Chief Financial Officer

DELFI Diagnostics appoints Thomas Russo as Chief Financial Officer.

Finsmes
Jun 5th, 2024
DELFI Diagnostics Receives Equity Investment From Merck Global Health Innovation Fund

DELFI Diagnostics receives equity investment from Merck Global Health Innovation Fund.

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